A study of respiratory illnesses in infants and nitrogen dioxide exposure

J. M. Samet, William Lambert, B. J. Skipper, A. H. Cushing, L. C. McLaren, M. Schwab, J. D. Spengler

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Toxicologic and epidemiologic studies have elevated concern that exposure to nitrogen dioxide (NO2) in outdoor and indoor air may increase the frequency and severity of respiratory infections. We have developed and implemented a prospective cohort study to test the hypothesis that exposure to NO2 increases the incidence and severity of respiratory infections during the first 18 mo of life. This study, which was based on extensive pilot research, was designed to address the potential limitations of misclassification, confounding, and inadequate power. Enrollment of 1 315 subjects has been completed. This paper reviews the methods used in the study, characteristics of the enrolled subjects, NO2 concentrations in the homes of study participants, and rates of illness occurrence.

Original languageEnglish (US)
Pages (from-to)57-63
Number of pages7
JournalArchives of Environmental Health
Volume47
Issue number1
StatePublished - 1992
Externally publishedYes

Fingerprint

Nitrogen Dioxide
nitrogen dioxide
Respiratory Tract Infections
indoor air
Air
Epidemiologic Studies
Cohort Studies
Prospective Studies
Incidence
Research
infant
exposure
infection
test
method
rate

ASJC Scopus subject areas

  • Environmental Science(all)
  • Environmental Chemistry
  • Public Health, Environmental and Occupational Health

Cite this

Samet, J. M., Lambert, W., Skipper, B. J., Cushing, A. H., McLaren, L. C., Schwab, M., & Spengler, J. D. (1992). A study of respiratory illnesses in infants and nitrogen dioxide exposure. Archives of Environmental Health, 47(1), 57-63.

A study of respiratory illnesses in infants and nitrogen dioxide exposure. / Samet, J. M.; Lambert, William; Skipper, B. J.; Cushing, A. H.; McLaren, L. C.; Schwab, M.; Spengler, J. D.

In: Archives of Environmental Health, Vol. 47, No. 1, 1992, p. 57-63.

Research output: Contribution to journalArticle

Samet, JM, Lambert, W, Skipper, BJ, Cushing, AH, McLaren, LC, Schwab, M & Spengler, JD 1992, 'A study of respiratory illnesses in infants and nitrogen dioxide exposure', Archives of Environmental Health, vol. 47, no. 1, pp. 57-63.
Samet JM, Lambert W, Skipper BJ, Cushing AH, McLaren LC, Schwab M et al. A study of respiratory illnesses in infants and nitrogen dioxide exposure. Archives of Environmental Health. 1992;47(1):57-63.
Samet, J. M. ; Lambert, William ; Skipper, B. J. ; Cushing, A. H. ; McLaren, L. C. ; Schwab, M. ; Spengler, J. D. / A study of respiratory illnesses in infants and nitrogen dioxide exposure. In: Archives of Environmental Health. 1992 ; Vol. 47, No. 1. pp. 57-63.
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