A simple specific assay for estriol in maternal urine

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

In medical centers with many high risk pregnancies, the ability to perform a large number of urinary estriol measurements is required. The analytical procedure should provide simplicity, specificity, and economy. A solid phase radioimmunoassay is presented which utilizes antibody generated against an estriol 16 glucuronide bovine serum albumin conjugate. The assay allows analysis of the principal component of maternal urinary estriol without hydrolysis or purification, with adequate specificity and the capacity for processing large numbers of samples.

Original languageEnglish (US)
Pages (from-to)895-900
Number of pages6
JournalJournal of Clinical Endocrinology and Metabolism
Volume40
Issue number5
StatePublished - 1975
Externally publishedYes

Fingerprint

Estriol
Assays
Mothers
Urine
High-Risk Pregnancy
Bovine Serum Albumin
Principal Component Analysis
Radioimmunoassay
Hydrolysis
Glucuronides
Purification
Antibodies
Processing
estriol glucuronide

ASJC Scopus subject areas

  • Biochemistry
  • Endocrinology, Diabetes and Metabolism

Cite this

A simple specific assay for estriol in maternal urine. / Davis, S. E.; Loriaux, Donald (Lynn).

In: Journal of Clinical Endocrinology and Metabolism, Vol. 40, No. 5, 1975, p. 895-900.

Research output: Contribution to journalArticle

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