A Retrospective Study of Clinical Effects of Powdered Caffeine Exposures Reported to Three US Poison Control Centers

Gillian A. Beauchamp, Amberly R. Johnson, Barbara I. Crouch, Matthew Valento, B (Zane) Horowitz, Robert Hendrickson

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Introduction: Anhydrous caffeine, often sold on the Internet as a powdered caffeine product, is sold as “pure caffeine” to be used as an additive to beverages and has also been used as an ingredient in energy supplement products. Methods: This is a retrospective multiple-poison center chart review of calls regarding powdered caffeine to poison centers covering Oregon, Alaska, Guam, Washington, and Utah between January 1, 2013 and June 30, 2015. Results: There were 40 calls to three poison centers over 30 months for powdered caffeine exposure. The majority of patients were over age 19 (52.5 %; 21/40) and male (70 %; 28/40). Sixty percent (24/40) of the patients were symptomatic but only 10 % (4/40) required admission; 52.5 % (21/40) of the patient calls were for inadvertent overdose of powdered caffeine; one patient overdosed in a self-harm attempt. Discussion: Powdered caffeine calls to three poison centers during a 30-month study period were rare, and severe caffeine toxicity due to exposure was found in few patients. The majority of symptoms were reported after an inadvertent powdered caffeine overdose. Conclusions: An analysis of calls to three poison centers for powdered caffeine found that exposures were uncommon, but did result in toxicity, and highlighted that the lack of clear dosing instructions on product packaging may place patients at risk of inadvertent overdose.

Original languageEnglish (US)
Pages (from-to)1-6
Number of pages6
JournalJournal of Medical Toxicology
DOIs
StateAccepted/In press - Apr 4 2016

Fingerprint

Poison Control Centers
Poisons
Caffeine
Retrospective Studies
Toxicity
Guam
Beverages
Product Packaging
Internet
Packaging

Keywords

  • Dietary supplement
  • Poison center
  • Powdered caffeine

ASJC Scopus subject areas

  • Health, Toxicology and Mutagenesis
  • Toxicology

Cite this

A Retrospective Study of Clinical Effects of Powdered Caffeine Exposures Reported to Three US Poison Control Centers. / Beauchamp, Gillian A.; Johnson, Amberly R.; Crouch, Barbara I.; Valento, Matthew; Horowitz, B (Zane); Hendrickson, Robert.

In: Journal of Medical Toxicology, 04.04.2016, p. 1-6.

Research output: Contribution to journalArticle

@article{60df3b91a2a04b439d3d212c0d7f5bf3,
title = "A Retrospective Study of Clinical Effects of Powdered Caffeine Exposures Reported to Three US Poison Control Centers",
abstract = "Introduction: Anhydrous caffeine, often sold on the Internet as a powdered caffeine product, is sold as “pure caffeine” to be used as an additive to beverages and has also been used as an ingredient in energy supplement products. Methods: This is a retrospective multiple-poison center chart review of calls regarding powdered caffeine to poison centers covering Oregon, Alaska, Guam, Washington, and Utah between January 1, 2013 and June 30, 2015. Results: There were 40 calls to three poison centers over 30 months for powdered caffeine exposure. The majority of patients were over age 19 (52.5 {\%}; 21/40) and male (70 {\%}; 28/40). Sixty percent (24/40) of the patients were symptomatic but only 10 {\%} (4/40) required admission; 52.5 {\%} (21/40) of the patient calls were for inadvertent overdose of powdered caffeine; one patient overdosed in a self-harm attempt. Discussion: Powdered caffeine calls to three poison centers during a 30-month study period were rare, and severe caffeine toxicity due to exposure was found in few patients. The majority of symptoms were reported after an inadvertent powdered caffeine overdose. Conclusions: An analysis of calls to three poison centers for powdered caffeine found that exposures were uncommon, but did result in toxicity, and highlighted that the lack of clear dosing instructions on product packaging may place patients at risk of inadvertent overdose.",
keywords = "Dietary supplement, Poison center, Powdered caffeine",
author = "Beauchamp, {Gillian A.} and Johnson, {Amberly R.} and Crouch, {Barbara I.} and Matthew Valento and Horowitz, {B (Zane)} and Robert Hendrickson",
year = "2016",
month = "4",
day = "4",
doi = "10.1007/s13181-016-0545-9",
language = "English (US)",
pages = "1--6",
journal = "Journal of Medical Toxicology",
issn = "1556-9039",
publisher = "Springer New York",

}

TY - JOUR

T1 - A Retrospective Study of Clinical Effects of Powdered Caffeine Exposures Reported to Three US Poison Control Centers

AU - Beauchamp, Gillian A.

AU - Johnson, Amberly R.

AU - Crouch, Barbara I.

AU - Valento, Matthew

AU - Horowitz, B (Zane)

AU - Hendrickson, Robert

PY - 2016/4/4

Y1 - 2016/4/4

N2 - Introduction: Anhydrous caffeine, often sold on the Internet as a powdered caffeine product, is sold as “pure caffeine” to be used as an additive to beverages and has also been used as an ingredient in energy supplement products. Methods: This is a retrospective multiple-poison center chart review of calls regarding powdered caffeine to poison centers covering Oregon, Alaska, Guam, Washington, and Utah between January 1, 2013 and June 30, 2015. Results: There were 40 calls to three poison centers over 30 months for powdered caffeine exposure. The majority of patients were over age 19 (52.5 %; 21/40) and male (70 %; 28/40). Sixty percent (24/40) of the patients were symptomatic but only 10 % (4/40) required admission; 52.5 % (21/40) of the patient calls were for inadvertent overdose of powdered caffeine; one patient overdosed in a self-harm attempt. Discussion: Powdered caffeine calls to three poison centers during a 30-month study period were rare, and severe caffeine toxicity due to exposure was found in few patients. The majority of symptoms were reported after an inadvertent powdered caffeine overdose. Conclusions: An analysis of calls to three poison centers for powdered caffeine found that exposures were uncommon, but did result in toxicity, and highlighted that the lack of clear dosing instructions on product packaging may place patients at risk of inadvertent overdose.

AB - Introduction: Anhydrous caffeine, often sold on the Internet as a powdered caffeine product, is sold as “pure caffeine” to be used as an additive to beverages and has also been used as an ingredient in energy supplement products. Methods: This is a retrospective multiple-poison center chart review of calls regarding powdered caffeine to poison centers covering Oregon, Alaska, Guam, Washington, and Utah between January 1, 2013 and June 30, 2015. Results: There were 40 calls to three poison centers over 30 months for powdered caffeine exposure. The majority of patients were over age 19 (52.5 %; 21/40) and male (70 %; 28/40). Sixty percent (24/40) of the patients were symptomatic but only 10 % (4/40) required admission; 52.5 % (21/40) of the patient calls were for inadvertent overdose of powdered caffeine; one patient overdosed in a self-harm attempt. Discussion: Powdered caffeine calls to three poison centers during a 30-month study period were rare, and severe caffeine toxicity due to exposure was found in few patients. The majority of symptoms were reported after an inadvertent powdered caffeine overdose. Conclusions: An analysis of calls to three poison centers for powdered caffeine found that exposures were uncommon, but did result in toxicity, and highlighted that the lack of clear dosing instructions on product packaging may place patients at risk of inadvertent overdose.

KW - Dietary supplement

KW - Poison center

KW - Powdered caffeine

UR - http://www.scopus.com/inward/record.url?scp=84962146774&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84962146774&partnerID=8YFLogxK

U2 - 10.1007/s13181-016-0545-9

DO - 10.1007/s13181-016-0545-9

M3 - Article

SP - 1

EP - 6

JO - Journal of Medical Toxicology

JF - Journal of Medical Toxicology

SN - 1556-9039

ER -