A randomized study of intravenous fluid replacement following living-donor renal transplantation

David A. Hatch, John Barry, Douglas Norman

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Fourteen adult recipients of living-donor kidneys preserved with ice-cold intracellular electrolyte solution were randomly assigned to receive either high fluid replacement (total volume of urine output + 30 ml/hr) or low fluid replacement (constant 125 ml/hr) during the first 48 hr after grafting. High replacement recipients had significantly higher fluid intake and urine output than did low replacement recipients. However, net fluid balance at the end of the 48-hr study period was positive for both groups and not significantly different. Fractional excretion of sodium was directly related to urine output in all patients. Serum osmolality, serum sodium concentration, and urine sodium concentration were not significantly different in the treatment groups. Urine osmolality was significantly higher in the lowreplacement group at 24 and 36 hr after transplantation. The i.v. replacement of total urinary output is unnecessary in adult recipients of living-donor kidneys preserved with ice-cold intracellular electrolyte solution because such grafts can conserve sodium and water immediately after transplantation.

Original languageEnglish (US)
Pages (from-to)648-650
Number of pages3
JournalTransplantation
Volume40
Issue number6
StatePublished - 1985

Fingerprint

Living Donors
Kidney Transplantation
Urine
Sodium
Ice
Osmolar Concentration
Electrolytes
Transplantation
Kidney
Water-Electrolyte Balance
Serum
Transplants
Water

ASJC Scopus subject areas

  • Transplantation
  • Immunology

Cite this

A randomized study of intravenous fluid replacement following living-donor renal transplantation. / Hatch, David A.; Barry, John; Norman, Douglas.

In: Transplantation, Vol. 40, No. 6, 1985, p. 648-650.

Research output: Contribution to journalArticle

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