A Randomized Clinical Trial of Energy Conservation for Patients with Cancer-Related Fatigue

Andrea M. Barsevick, William Dudley, Susan Beck, Carole Sweeney, Kyra Whitmer, Lillian Nail

    Research output: Contribution to journalArticle

    136 Citations (Scopus)

    Abstract

    BACKGROUND. The efficacy of energy conservation and activity management (ECAM) for fatigue reduction and maintenance of functional performance has never been evaluated in adults with cancer who are undergoing treatment. METHODS. A randomized clinical trial compared an ECAM intervention with a control intervention focused on nutrition. Individuals initiating chemotherapy, radiotherapy, or concurrent therapy for cancer were randomized to receive either the semistructured ECAM intervention (n = 200) or the control intervention (n = 196). Participants in each group participated in 3 telephone sessions with an oncology nurse during the first 5 weeks of treatment. Data on fatigue and limitation of functioning were obtained before cancer treatment and at two follow-up points that coincided with times of high fatigue for each type of treatment. The outcomes of interest included perception of fatigue and functional performance. RESULTS. A repeated - measures analysis of covariance using the type of cancer treatment as a covariate revealed a significant study group-by-time interaction indicating that the ECAM group experienced a greater decrease in fatigue over time compared with the control group (F 2.544 = 4.5; P = 0.01). The intervention was not associated with changes in overall functional performance. CONCLUSIONS. Individuals who received the ECAM intervention derived a modest but significant benefit from it. To achieve a more robust clinical benefit from the intervention, it may be necessary to manage other key symptoms in addition to fatigue. Research is needed to examine symptom clusters or combinations associated with negative outcomes as well as combination strategies for symptom management.

    Original languageEnglish (US)
    Pages (from-to)1302-1310
    Number of pages9
    JournalCancer
    Volume100
    Issue number6
    DOIs
    StatePublished - Mar 15 2004

    Fingerprint

    Fatigue
    Randomized Controlled Trials
    Neoplasms
    Therapeutics
    Telephone
    Radiotherapy
    Nurses
    Maintenance
    Drug Therapy
    Control Groups
    Research

    Keywords

    • Fatigue
    • Quality of life
    • Symptom clusters
    • Symptom management

    ASJC Scopus subject areas

    • Cancer Research
    • Oncology

    Cite this

    Barsevick, A. M., Dudley, W., Beck, S., Sweeney, C., Whitmer, K., & Nail, L. (2004). A Randomized Clinical Trial of Energy Conservation for Patients with Cancer-Related Fatigue. Cancer, 100(6), 1302-1310. https://doi.org/10.1002/cncr.20111

    A Randomized Clinical Trial of Energy Conservation for Patients with Cancer-Related Fatigue. / Barsevick, Andrea M.; Dudley, William; Beck, Susan; Sweeney, Carole; Whitmer, Kyra; Nail, Lillian.

    In: Cancer, Vol. 100, No. 6, 15.03.2004, p. 1302-1310.

    Research output: Contribution to journalArticle

    Barsevick, AM, Dudley, W, Beck, S, Sweeney, C, Whitmer, K & Nail, L 2004, 'A Randomized Clinical Trial of Energy Conservation for Patients with Cancer-Related Fatigue', Cancer, vol. 100, no. 6, pp. 1302-1310. https://doi.org/10.1002/cncr.20111
    Barsevick AM, Dudley W, Beck S, Sweeney C, Whitmer K, Nail L. A Randomized Clinical Trial of Energy Conservation for Patients with Cancer-Related Fatigue. Cancer. 2004 Mar 15;100(6):1302-1310. https://doi.org/10.1002/cncr.20111
    Barsevick, Andrea M. ; Dudley, William ; Beck, Susan ; Sweeney, Carole ; Whitmer, Kyra ; Nail, Lillian. / A Randomized Clinical Trial of Energy Conservation for Patients with Cancer-Related Fatigue. In: Cancer. 2004 ; Vol. 100, No. 6. pp. 1302-1310.
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