A prospective, randomized study of testosterone treatment of constitutional delay of growth and development in male adolescents

Ronald (Ron) Rosenfeld, G. B. Northcraft, R. L. Hintz

Research output: Contribution to journalArticle

62 Citations (Scopus)

Abstract

The physiologic and psychological responses to androgen treatment of constitutional delay of growth and development were prospectively evaluated in 16 male adolescents, aged 14 to 17 years. Subjects were randomly assigned to a course of testosterone enanthate, 200 mg administered intramuscularly four times at three-week intervals or to observation. At one-year follow-up all subjects in the testosterone group exhibited excellent growth: 7.2 to 11.6 cm/yr (mean 9.2 cm/yr). Growth in control subjects was highly variable: 2.6 to 10.6 cm/yr (mean 6.0 cm/yr), significantly lower than that of the testosterone group (P

Original languageEnglish (US)
Pages (from-to)681-687
Number of pages7
JournalPediatrics
Volume69
Issue number6
StatePublished - 1982
Externally publishedYes

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Growth and Development
Testosterone
Prospective Studies
Growth
Androgens
Observation
Psychology
Therapeutics
testosterone enanthate

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

A prospective, randomized study of testosterone treatment of constitutional delay of growth and development in male adolescents. / Rosenfeld, Ronald (Ron); Northcraft, G. B.; Hintz, R. L.

In: Pediatrics, Vol. 69, No. 6, 1982, p. 681-687.

Research output: Contribution to journalArticle

Rosenfeld, Ronald (Ron) ; Northcraft, G. B. ; Hintz, R. L. / A prospective, randomized study of testosterone treatment of constitutional delay of growth and development in male adolescents. In: Pediatrics. 1982 ; Vol. 69, No. 6. pp. 681-687.
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