A clinicopathologic correlative study of noncontact transscleral Nd:YAG cyclophotocoagulation

P. Marsh, D. J. Wilson, J. R. Samples, J. C. Morrison

Research output: Contribution to journalArticle

16 Scopus citations

Abstract

We studied the histopathologic changes of three eyes enucleated two weeks, eight weeks, and 17 months, respectively, after noncontact Nd:YAG cyclophotocoagulation. The histologic findings at two weeks were destruction of the nonpigmented and pigmented ciliary body epithelium, occlusion of the capillaries of the ciliary processes, and ciliary body stromal necrosis in the region of the processes. Hyperplasia of the pigmented and nonpigmented epithelium, fibrosis and near total atrophy of the ciliary processes, and partial atrophy of the ciliary muscles were present at eight weeks and 17 months. We concluded that application of treatment 1.0 to 1.5 mm posterior to the corneoscleral limbus selectively destroys the pars plicata, and that, histologically, the mechanism for reducing intraocular pressure appears to be destruction of ciliary processes with reduction of aqueous formation.

Original languageEnglish (US)
Pages (from-to)597-602
Number of pages6
JournalAmerican journal of ophthalmology
Volume115
Issue number5
DOIs
StatePublished - Jan 1 1993

    Fingerprint

ASJC Scopus subject areas

  • Ophthalmology

Cite this