Abstract
In this article, an automatic method for measuring 3-dimensional (3D) anterior chamber eye angle opening distance (AOD) with Fourier-domain optical coherence tomography (OCT) was proposed. A special 3D "Angle Arc" scan pattern composed of 25 cross-sectional OCT image frames was designed. The initial boundaries of the anterior and posterior cornea and anterior iris were located in all the frames and then refined. Human input was needed to identify Schwalbe's line (SL) in 3 key frames of each 3D dataset. Next, the computer algorithm was employed to estimate SL locations in the rest 22 frames according to a mapping method. Last, the angle opening distance based on the SL (AOD-SL) was calculated for all the frames. Result showed that the computer algorithm provided a robust and accurate method to measure 3D AOD-SL. The precise angle boundary detection was 96.06% in image frames, and accuracy of the AOD-SL measurement in the key frames was 95.11% by using the automated AOD-SL measurements. The automated AOD-SL measurements agreed well with the human measurements with computer calipers.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 831-838 |
| Number of pages | 8 |
| Journal | Chinese Journal of Biomedical Engineering |
| Volume | 31 |
| Issue number | 6 |
| DOIs | |
| State | Published - Dec 20 2012 |
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Keywords
- 3-dimensional anterior chamber angle scan pattern
- Angle opening distance
- Anterior chamber angle imaging
- Image segmentation
- Optical coherence tomography
ASJC Scopus subject areas
- Medicine (miscellaneous)
- Biomedical Engineering
- Bioengineering
Cite this
3D anterior chamber angle measurements with high resolution Fourier-domain optical coherence tomography. / Wu, Wei; Duan, Hui Long; Li, Yan; Jiang, Chun Hui; Qin, Bing; Huang, David.
In: Chinese Journal of Biomedical Engineering, Vol. 31, No. 6, 20.12.2012, p. 831-838.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - 3D anterior chamber angle measurements with high resolution Fourier-domain optical coherence tomography
AU - Wu, Wei
AU - Duan, Hui Long
AU - Li, Yan
AU - Jiang, Chun Hui
AU - Qin, Bing
AU - Huang, David
PY - 2012/12/20
Y1 - 2012/12/20
N2 - In this article, an automatic method for measuring 3-dimensional (3D) anterior chamber eye angle opening distance (AOD) with Fourier-domain optical coherence tomography (OCT) was proposed. A special 3D "Angle Arc" scan pattern composed of 25 cross-sectional OCT image frames was designed. The initial boundaries of the anterior and posterior cornea and anterior iris were located in all the frames and then refined. Human input was needed to identify Schwalbe's line (SL) in 3 key frames of each 3D dataset. Next, the computer algorithm was employed to estimate SL locations in the rest 22 frames according to a mapping method. Last, the angle opening distance based on the SL (AOD-SL) was calculated for all the frames. Result showed that the computer algorithm provided a robust and accurate method to measure 3D AOD-SL. The precise angle boundary detection was 96.06% in image frames, and accuracy of the AOD-SL measurement in the key frames was 95.11% by using the automated AOD-SL measurements. The automated AOD-SL measurements agreed well with the human measurements with computer calipers.
AB - In this article, an automatic method for measuring 3-dimensional (3D) anterior chamber eye angle opening distance (AOD) with Fourier-domain optical coherence tomography (OCT) was proposed. A special 3D "Angle Arc" scan pattern composed of 25 cross-sectional OCT image frames was designed. The initial boundaries of the anterior and posterior cornea and anterior iris were located in all the frames and then refined. Human input was needed to identify Schwalbe's line (SL) in 3 key frames of each 3D dataset. Next, the computer algorithm was employed to estimate SL locations in the rest 22 frames according to a mapping method. Last, the angle opening distance based on the SL (AOD-SL) was calculated for all the frames. Result showed that the computer algorithm provided a robust and accurate method to measure 3D AOD-SL. The precise angle boundary detection was 96.06% in image frames, and accuracy of the AOD-SL measurement in the key frames was 95.11% by using the automated AOD-SL measurements. The automated AOD-SL measurements agreed well with the human measurements with computer calipers.
KW - 3-dimensional anterior chamber angle scan pattern
KW - Angle opening distance
KW - Anterior chamber angle imaging
KW - Image segmentation
KW - Optical coherence tomography
UR - http://www.scopus.com/inward/record.url?scp=84872711316&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84872711316&partnerID=8YFLogxK
U2 - 10.3969/j.issn.0258-8021.2012.06.005
DO - 10.3969/j.issn.0258-8021.2012.06.005
M3 - Article
AN - SCOPUS:84872711316
VL - 31
SP - 831
EP - 838
JO - Zhongguo Shengwu Yixue Gongcheng Xuebao/Chinese Journal of Biomedical Engineering
JF - Zhongguo Shengwu Yixue Gongcheng Xuebao/Chinese Journal of Biomedical Engineering
SN - 0258-8021
IS - 6
ER -