3,3′-diindolylmethane induces g ₁ arrest and apoptosis in human acute t-cell lymphoblastic leukemia cells

Agriculture & Biology

• lymphocytic leukemia 82%
• apoptosis 55%
• T-lymphocytes 54%
• indoles 51%
• mice 20%
• bioactive food compounds 19%
• human growth 19%
• cells 19%
• chemoprevention 16%
• antineoplastic activity 16%
• dietary exposure 15%
• cyclin-dependent kinase 15%
• cyclins 14%
• lymphoma 14%
• carcinogenesis 12%
• cell viability 11%
• neoplasm cells 10%
• cell proliferation 10%
• cell cycle 10%
• animal models 10%
• cell culture 9%
• vegetables 9%
• therapeutics 9%
• neoplasms 9%
• protein synthesis 9%
• cell lines 8%

Medicine & Life Sciences

• 3,3'-diindolylmethane 100%
• Precursor Cell Lymphoblastic Leukemia-Lymphoma 58%
• indole-3-carbinol 37%
• Apoptosis 36%
• Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 31%
• TNF Receptor-Associated Factor 4 11%
• dibenzo(a,l)pyrene 11%
• Cyclin-Dependent Kinase 6 9%
• Cyclin-Dependent Kinase 4 8%
• Cyclin D 8%
• Dietary Exposure 8%
• Gastrin-Secreting Cells 7%
• T-Cell Lymphoma 6%
• Chemoprevention 6%
• Vegetables 5%
• Heterografts 5%
• Cell Cycle 4%
• Carcinogenesis 4%
• Cell Culture Techniques 4%
• Food 4%
• Cell Proliferation 3%
• Neoplasms 3%
• Cell Line 3%
• Growth 3%
• In Vitro Techniques 2%
• Proteins 2%
• Therapeutics 1%

Chemical Compounds

• Apoptotic 68%
• Food Component 42%
• Chemopreventive 42%
• Chrysene 40%
• Protein 12%
• Application 9%