Phillip Yates

Research Assistant Professor

  • 560 Citations
  • 15 h-Index
19972017
If you made any changes in Pure, your changes will be visible here soon.

Research Output 1998 2017

  • 560 Citations
  • 15 h-Index
  • 26 Article
Filter
Article
2017
18 Citations (Scopus)

Arginase is essential for survival of Leishmania donovani promastigotes but not intracellular amastigotes

Boitz, J. M., Gilroy, C. A., Olenyik, T. D., Paradis, D., Perdeh, J., Dearman, K., Davis, M. J., Yates, P., Li, Y., Riscoe, M., Ullman, B. & Roberts, S. C., 2017, In : Infection and Immunity. 85, 1, e00554-16.

Research output: Contribution to journalArticle

Leishmania donovani
Arginase
Polyamines
Ornithine
Parasites
2016
7 Citations (Scopus)

A role for adenine nucleotides in the sensing mechanism to purine starvation in Leishmania donovani

Martin, J. L., Yates, P., Boitz, J. M., Koop, D., Fulwiler, A. L., Cassera, M. B., Ullman, B. & Carter, N., Jul 1 2016, In : Molecular Microbiology. 101, 2, p. 299-313 15 p.

Research output: Contribution to journalArticle

Leishmania donovani
Adenine Nucleotides
Starvation
Purines
Leishmania
3 Citations (Scopus)

Comparing lamin proteins post-translational relative stability using a 2A peptide-based system reveals elevated resistance of progerin to cellular degradation

Wu, D., Yates, P., Zhang, H. & Cao, K., Nov 1 2016, In : Nucleus. 7, 6, p. 585-596 12 p.

Research output: Contribution to journalArticle

Lamins
Lamin Type A
Peptides
Nuclear Envelope
Proteins
2015
2 Citations (Scopus)

Integrating ribosomal promoter vectors that offer a choice of constitutive expression profiles in Leishmania donovani

Soysa, R., Tran, K. D., Ullman, B. & Yates, P., Dec 1 2015, In : Molecular and Biochemical Parasitology. 204, 2, p. 89-92 4 p.

Research output: Contribution to journalArticle

Leishmania donovani
Ribosomal RNA
RNA Precursors
RNA Stability
Transgenes
15 Citations (Scopus)

Regulation and biological function of a flagellar glucose transporter in Leishmania mexicana: A potential glucose sensor

Rodriguez-Contreras, D., Aslan, H., Feng, X., Tran, K., Yates, P., Kamhawi, S. & Landfear, S., Jan 1 2015, In : FASEB Journal. 29, 1, p. 11-24 14 p.

Research output: Contribution to journalArticle

Glucose sensors
Facilitative Glucose Transport Proteins
Glucose
Parasites
Leishmania mexicana
2014
7 Citations (Scopus)

A dual luciferase system for analysis of post-transcriptional regulation of gene expression in Leishmania

Soysa, R., Carter, N. & Yates, P., 2014, In : Molecular and Biochemical Parasitology. 195, 1, p. 1-5 5 p.

Research output: Contribution to journalArticle

Leishmania
Gene Expression Regulation
Systems Analysis
Luciferases
Genes
32 Citations (Scopus)

Metabolic Reprogramming during Purine Stress in the Protozoan Pathogen Leishmania donovani

Martin, J. L., Yates, P., Soysa, R., Alfaro, J. F., Yang, F., Burnum-Johnson, K. E., Petyuk, V. A., Weitz, K. K., Camp, D. G., Smith, R. D., Wilmarth, P., David, L., Ramasamy, G., Myler, P. J. & Carter, N., 2014, In : PLoS Pathogens. 10, 2, e1003938.

Research output: Contribution to journalArticle

Leishmania donovani
Parasites
Starvation
Proteome
purine
2013
22 Citations (Scopus)

Adenylosuccinate synthetase and adenylosuccinate lyase deficiencies trigger growth and infectivity deficits in Leishmania donovani

Boitz, J. M., Strasser, R., Yates, P., Jardim, A. & Ullman, B., Mar 29 2013, In : Journal of Biological Chemistry. 288, 13, p. 8977-8990 14 p.

Research output: Contribution to journalArticle

Adenylosuccinate Synthase
Adenylosuccinate Lyase
Leishmania donovani
Salvaging
Growth
10 Citations (Scopus)

KHARON1 mediates flagellar targeting of a glucose transporter in Leishmania mexicana and is critical for viability of infectious intracellular amastigotes

Tran, K. D., Rodriguez-Contreras, D., Vieira, D. P., Yates, P., David, L., Beatty, W., Elferich, J. & Landfear, S., Aug 2 2013, In : Journal of Biological Chemistry. 288, 31, p. 22721-22733 13 p.

Research output: Contribution to journalArticle

Facilitative Glucose Transport Proteins
Flagella
Membrane Proteins
Kinetoplastida
Parasites
8 Citations (Scopus)

Substrate inhibition of uracil phosphoribosyltransferase by uracil can account for the uracil growth sensitivity of leishmania donovani pyrimidine auxotrophs

Soysa, R., Wilson, Z. N., Elferich, J., Forquer, I., Shinde, U., Riscoe, M., Yates, P. & Ullman, B., Oct 11 2013, In : Journal of Biological Chemistry. 288, 41, p. 29954-29964 11 p.

Research output: Contribution to journalArticle

uracil phosphoribosyltransferase
Leishmania donovani
Uracil
Salvaging
Substrates
2012
19 Citations (Scopus)

Genetic dissection of pyrimidine biosynthesis and salvage in Leishmania donovani

Wilson, Z. N., Gilroy, C. A., Boitz, J. M., Ullman, B. & Yates, P., Apr 13 2012, In : Journal of Biological Chemistry. 287, 16, p. 12759-12770 12 p.

Research output: Contribution to journalArticle

Leishmania donovani
Salvaging
Dissection
uracil phosphoribosyltransferase
Biosynthesis
2011
Alleles
DNA Methylation
Methylation
Histone Code
Embryonal Carcinoma Stem Cells
20 Citations (Scopus)

A rapid, efficient and economical method for generating leishmanial gene targeting constructs

Fulwiler, A. L., Soysa, D. R., Ullman, B. & Yates, P., Feb 2011, In : Molecular and Biochemical Parasitology. 175, 2, p. 209-212 4 p.

Research output: Contribution to journalArticle

Gene Targeting
Leishmania donovani
Inosine Monophosphate
Genes
Ligation
1 Citation (Scopus)

Characterization of amplicons that suppress the conditional lethal growth phenotype of a Leishmania donovani mutant lacking normal purine salvage mechanisms

Fulwiler, A. L., Boitz, J. M., Yates, P., Carter, N. & Ullman, B., Jan 2011, In : Molecular and Biochemical Parasitology. 175, 1, p. 76-82 7 p.

Research output: Contribution to journalArticle

Leishmania donovani
Pulsed Field Gel Electrophoresis
Adenine Phosphoribosyltransferase
Phenotype
Hypoxanthine Phosphoribosyltransferase
13 Citations (Scopus)

IMP dehydrogenase deficiency in Leishmania donovani causes a restrictive growth phenotype in promastigotes but is not essential for infection in mice

Fulwiler, A. L., Boitz, J. M., Gilroy, C., Yates, P., Jardim, A. & Ullman, B., Dec 2011, In : Molecular and Biochemical Parasitology. 180, 2, p. 123-126 4 p.

Research output: Contribution to journalArticle

IMP Dehydrogenase
Leishmania donovani
Guanine
Inosine Monophosphate
Purines
28 Citations (Scopus)

The Leishmania donovani UMP synthase is essential for promastigote viability and has an unusual tetrameric structure that exhibits substrate-controlled oligomerization

French, J. B., Yates, P., Soysa, D. R., Boitz, J. M., Carter, N., Chang, B., Ullman, B. & Ealick, S. E., Jun 10 2011, In : Journal of Biological Chemistry. 286, 23, p. 20930-20941 12 p.

Research output: Contribution to journalArticle

Leishmania donovani
Oligomerization
Transferases
Carboxy-Lyases
Uridine Monophosphate
2010
31 Citations (Scopus)

Adaptive responses to purine starvation in Leishmania donovani

Carter, N., Yates, P., Gessford, S. K., Galagan, S. R., Landfear, S. & Ullman, B., Oct 2010, In : Molecular Microbiology. 78, 1, p. 92-107 16 p.

Research output: Contribution to journalArticle

Leishmania donovani
Starvation
Purine Nucleosides
Purines
Parasites
2009
45 Citations (Scopus)

Leishmania donovani ornithine decarboxylase is indispensable for parasite survival in the mammalian host

Boitz, J. M., Yates, P., Kline, C., Gaur, U., Wilson, M. E., Ullman, B. & Roberts, S. C., Feb 2009, In : Infection and Immunity. 77, 2, p. 756-763 8 p.

Research output: Contribution to journalArticle

Leishmania donovani
Ornithine Decarboxylase
Polyamines
Parasites
Macrophages
2008
61 Citations (Scopus)

Purine and pyrimidine metabolism in Leishmania

Ullman, B., Carter, N., Yates, P., Arendt, C. S. & Boitz, J. M., 2008, In : Advances in Experimental Medicine and Biology. 625, p. 141-154 14 p.

Research output: Contribution to journalArticle

Leishmania
Metabolism
Salvaging
Pyrimidine Nucleotides
Pyrimidines
2007
13 Citations (Scopus)

Genetic selection for a highly functional cysteine-less membrane protein using site saturation mutagenesis

Arendt, C. S., Ri, K., Yates, P. & Ullman, B., Jun 15 2007, In : Analytical Biochemistry. 365, 2, p. 185-193 9 p.

Research output: Contribution to journalArticle

Mutagenesis
Genetic Selection
Cysteine
Inosine
Membrane Proteins
2003
20 Citations (Scopus)

Silencing of mouse Aprt is a gradual process in differentiated cells

Yates, P., Burman, R., Simpson, J., Ponomoreva, O. N., Thayer, M. M. & Turker, M., Jul 2003, In : Molecular and Cellular Biology. 23, 13, p. 4461-4470 10 p.

Research output: Contribution to journalArticle

decitabine
Methylation
Embryonal Carcinoma Stem Cells
Cell Fusion
DNA Methylation
2002
6 Citations (Scopus)

Regulation of peptidergic vesicle mobility by secretagogues

Washburn, C. L., Bean, J. E., Silverman, M. A., Pellegrino, M. J., Yates, P. & Allen, R. G., Nov 1 2002, In : Traffic. 3, 11, p. 801-809 9 p.

Research output: Contribution to journalArticle

Secretory Vesicles
Neuropeptides
Neurons
Green Fluorescent Proteins
Depolarization
2000
19 Citations (Scopus)

Biallelic methylation and silencing of mouse Aprt in normal kidney cells

Rose, J. A., Yates, P., Simpson, J., Tischfield, J. A., Stambrook, P. J. & Turker, M., Jul 1 2000, In : Cancer Research. 60, 13, p. 3404-3408 5 p.

Research output: Contribution to journalArticle

Adenine Phosphoribosyltransferase
Methylation
Kidney
Alleles
Gene Silencing
1999
15 Citations (Scopus)

Hypomethylation of an expanded FMR1 allele is not associated with a global DNA methylation defect

Burman, R. W., Yates, P., Green, L. D., Jacky, P. B., Turker, M. & Popovich, B. W., 1999, In : American Journal of Human Genetics. 65, 5, p. 1375-1386 12 p.

Research output: Contribution to journalArticle

DNA Methylation
Methylation
Alleles
Mutation
CpG Islands
71 Citations (Scopus)

Tandem B1 elements located in a mouse methylation center provide a target for de novo DNA methylation

Yates, P., Burman, R. W., Mummaneni, P., Krussel, S. & Turker, M., Dec 17 1999, In : Journal of Biological Chemistry. 274, 51, p. 36357-36361 5 p.

Research output: Contribution to journalArticle

Methylation
DNA Methylation
Embryonal Carcinoma Stem Cells
Stem cells
Stem Cells
1998
74 Citations (Scopus)

The primary function of a redundant Sp1 binding site in the mouse aprt gene promoter is to block epigenetic gene inactivation

Mummaneni, P., Yates, P., Simpson, J., Rose, J. & Turker, M., Nov 15 1998, In : Nucleic Acids Research. 26, 22, p. 5163-5169 7 p.

Research output: Contribution to journalArticle

Adenine Phosphoribosyltransferase
Gene Silencing
Epigenomics
Binding Sites
Genes