• 3801 Citations
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1985 …2020

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2020

Comparison of Mortality Among Participants of Women's Health Initiative Trials With Screening-Detected Breast Cancers vs Interval Breast Cancers

Irvin, V. L., Zhang, Z., Simon, M. S., Chlebowski, R. T., Luoh, S. W., Shadyab, A. H., Krok-Schoen, J. L., Tabung, F. K., Qi, L., Stefanick, M. L., Schedin, P. & Jindal, S., Jun 1 2020, In : JAMA Network Open. 3, 6, p. e207227

Research output: Contribution to journalArticle

Open Access

Erythrocyte membrane fatty acids and breast cancer risk by tumor tissue expression of immuno-inflammatory markers and fatty acid synthase: A nested case-control study

McGee, E. E., Kim, C. H., Wang, M., Spiegelman, D., Stover, D. G., Heng, Y. J., Collins, L. C., Baker, G. M., Farvid, M. S., Schedin, P., Jindal, S., Tamimi, R. M. & Eliassen, A. H., Jul 22 2020, In : Breast Cancer Research. 22, 1, 78.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2019

Association Between Postpartum Breast Cancer Diagnosis and Metastasis and the Clinical Features Underlying Risk

Goddard, E. T., Bassale, S., Schedin, T., Jindal, S., Johnston, J., Cabral, E., Latour, E., Lyons, T. R., Mori, M., Schedin, P. J. & Borges, V. F., Jan 4 2019, In : JAMA Network Open. 2, 1, p. e186997

Research output: Contribution to journalArticle

Open Access
15 Scopus citations

NHERF1 Is Required for Localization of PMCA2 and Suppression of Early Involution in the Female Lactating Mammary Gland

Jeong, J., Kim, W., Hens, J., Dann, P., Schedin, P., Friedman, P. A. & Wysolmerski, J. J., Jul 4 2019, In : Endocrinology. 160, 8, p. 1797-1810 14 p., 201900230.

Research output: Contribution to journalArticle

2 Scopus citations

RNA-seq from archival FFPE breast cancer samples: Molecular pathway fidelity and novel discovery

Pennock, N. D., Jindal, S., Horton, W., Sun, D., Narasimhan, J., Carbone, L., Fei, S. S., Searles, R., Harrington, C. A., Burchard, J., Weinmann, S., Schedin, P. & Xia, Z., Dec 19 2019, In : BMC Medical Genomics. 12, 1, 195.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2018
7 Scopus citations

Metformin inhibits stromal aromatase expression and tumor progression in a rodent model of postmenopausal breast cancer

Giles, E. D., Jindal, S., Wellberg, E. A., Schedin, T., Anderson, S. M., Thor, A. D., Edwards, D. P., MacLean, P. S. & Schedin, P., Jun 14 2018, In : Breast Cancer Research. 20, 1, 50.

Research output: Contribution to journalArticle

8 Scopus citations

Mucosal immunity in the female murine mammary gland

Betts, C. B., Pennock, N. D., Caruso, B. P., Ruffell, B., Borges, V. F. & Schedin, P., Jul 15 2018, In : Journal of Immunology. 201, 2, p. 734-746 13 p.

Research output: Contribution to journalArticle

13 Scopus citations

Semaphorin 7A promotes macrophage-mediated lymphatic remodeling during postpartum mammary gland involution and in breast cancer

Elder, A. M., Tamburini, B. A. J., Crump, L. S., Black, S. A., Wessells, V. M., Schedin, P. J., Borges, V. F. & Lyons, T. R., Nov 15 2018, In : Cancer Research. 78, 22, p. 6473-6485 13 p.

Research output: Contribution to journalArticle

12 Scopus citations
2017

IFPA meeting 2016 workshop report III: Decidua-trophoblast interactions; trophoblast implantation and invasion; immunology at the maternal-fetal interface; placental inflammation

Aplin, J. D., Beristain, A., DaSilva-Arnold, S., Dunk, C., Duzyj, C., Golos, T. G., Kemmerling, U., Knöfler, M., Mitchell, M. D., Olson, D. M., Petroff, M., Pollheimer, J., Reyes, L., Schedin, P., Soares, M. J., Stencel-Baerenwald, J., Thornburg, K. & Lash, G. E., Apr 13 2017, (Accepted/In press) In : Placenta.

Research output: Contribution to journalArticle

2 Scopus citations

Mammary extracellular matrix directs differentiation of testicular and embryonic stem cells to form functional mammary glands in vivo

Bruno, R. D., Fleming, J. M., George, A. L., Boulanger, C. A., Schedin, P. & Smith, G. H., Jan 10 2017, In : Scientific Reports. 7, 40196.

Research output: Contribution to journalArticle

17 Scopus citations

Metformin accumulation correlates with organic cation transporter 2 protein expression and predicts mammary tumor regression in vivo

Checkley, L. A., Rudolph, M. C., Wellberg, E. A., Giles, E. D., Wahdan-Alaswad, R. S., Houck, J. A., Edgerton, S. M., Thor, A. D., Schedin, P., Anderson, S. M. & MacLean, P. S., Mar 2017, In : Cancer Prevention Research. 10, 3, p. 198-207 10 p.

Research output: Contribution to journalArticle

15 Scopus citations

Physiologically activated mammary fibroblasts promote postpartum mammary cancer

Guo, Q., Minnier, J., Burchard, J., Chiotti, K., Spellman, P. & Schedin, P., Mar 23 2017, In : JCI Insight. 2, 6, p. e89206

Research output: Contribution to journalArticle

Open Access
11 Scopus citations

The Androgen Receptor Supports Tumor Progression After the Loss of Ovarian Function in a Preclinical Model of Obesity and Breast Cancer

Wellberg, E. A., Checkley, L. A., Giles, E. D., Johnson, S. J., Oljira, R., Wahdan-Alaswad, R., Foright, R. M., Dooley, G., Edgerton, S. M., Jindal, S., Johnson, G. C., Richer, J. K., Kabos, P., Thor, A. D., Schedin, P., MacLean, P. S. & Anderson, S. M., Dec 1 2017, In : Hormones and Cancer. 8, 5-6, p. 269-285 17 p.

Research output: Contribution to journalArticle

3 Scopus citations

The rodent liver undergoes weaning-induced involution and supports breast cancer metastasis

Goddard, E. T., Hill, R. C., Nemkov, T., D’Alessandro, A., Hansen, K. C., Maller, O., Mongoue-Tchokote, S., Mori, M., Partridge, A. H., Borges, V. F. & Schedin, P., Feb 2017, In : Cancer discovery. 7, 2, p. 177-187 11 p.

Research output: Contribution to journalArticle

15 Scopus citations
2016

A portal vein injection model to study liver metastasis of breast cancer

Goddard, E. T., Fischer, J. & Schedin, P., Dec 26 2016, In : Journal of Visualized Experiments. 2016, 118, p. 1-10 10 p., e54903.

Research output: Contribution to journalArticle

14 Scopus citations

Breast cancer risk factor associations differ for pure versus invasive carcinoma with an in situ component in case–control and case–case analyses

Ruszczyk, M., Zirpoli, G., Kumar, S., Bandera, E. V., Bovbjerg, D. H., Jandorf, L., Khoury, T., Hwang, H., Ciupak, G., Pawlish, K., Schedin, P., Masso-Welch, P., Ambrosone, C. B. & Hong, C. C., Feb 1 2016, In : Cancer Causes and Control. 27, 2, p. 183-198 16 p.

Research output: Contribution to journalArticle

4 Scopus citations

COX-2 modulates mammary tumor progression in response to collagen density

Esbona, K., Inman, D., Saha, S., Jeffery, J., Schedin, P., Wilke, L. & Keely, P., Mar 22 2016, In : Breast Cancer Research. 18, 1, 35.

Research output: Contribution to journalArticle

42 Scopus citations

Mammary epithelial cell phagocytosis downstream of TGF-β3 is characterized by adherens junction reorganization

Fornetti, J., Flanders, K. C., Henson, P. M., Tan, A. C., Borges, V. F. & Schedin, P., Feb 1 2016, In : Cell Death and Differentiation. 23, 2, p. 185-196 12 p.

Research output: Contribution to journalArticle

17 Scopus citations

Myoepithelial cells in lobular carcinoma in situ: Distribution and immunophenotype

Wang, Y., Jindal, S., Martel, M., Wu, Y., Schedin, P. & Troxell, M., Sep 1 2016, In : Human Pathology. 55, p. 126-134 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

Quantitative extracellular matrix proteomics to study mammary and liver tissue microenvironments

Goddard, E. T., Hill, R. C., Barrett, A., Betts, C., Guo, Q., Maller, O., Borges, V. F., Hansen, K. C. & Schedin, P., Dec 1 2016, In : International Journal of Biochemistry and Cell Biology. 81, p. 223-232 10 p.

Research output: Contribution to journalArticle

31 Scopus citations

XactMice: Humanizing mouse bone marrow enables microenvironment reconstitution in a patient-derived xenograft model of head and neck cancer

Morton, J. J., Bird, G., Keysar, S. B., Astling, D. P., Lyons, T. R., Anderson, R. T., Glogowska, M. J., Estes, P., Eagles, J. R., Le, P. N., Gan, G., McGettigan, B., Fernandez, P., Padilla-Just, N., Varella-Garcia, M., Song, J. I., Bowles, D. W., Schedin, P., Tan, A. C., Roop, D. R. & 3 others, Wang, X. J., Refaeli, Y. & Jimeno, A., Jan 21 2016, In : Oncogene. 35, 3, p. 290-300 11 p.

Research output: Contribution to journalArticle

63 Scopus citations
2015

A case-control analysis of oral contraceptive use and breast cancer subtypes in the African American Breast Cancer Epidemiology and Risk Consortium

Bethea, T. N., Rosenberg, L., Hong, C. C., Troester, M. A., Lunetta, K. L., Bandera, E. V., Schedin, P., Kolonel, L. N., Olshan, A. F., Ambrosone, C. B. & Palmer, J. R., Dec 14 2015, In : Breast Cancer Research. 17, 1, 22.

Research output: Contribution to journalArticle

23 Scopus citations

Important Role of Menarche in Development of Estrogen Receptor-Negative Breast Cancer in African American Women

Ambrosone, C. B., Zirpoli, G., Hong, C. C., Yao, S., Troester, M. A., Bandera, E. V., Schedin, P., Bethea, T. N., Borges, V., Park, S. Y., Chandra, D., Rosenberg, L., Kolonel, L. N., Olshan, A. F. & Palmer, J. R., Sep 1 2015, In : Journal of the National Cancer Institute. 107, 9, djv172.

Research output: Contribution to journalArticle

28 Scopus citations

Molecular phenotype of breast cancer according to time since last pregnancy in a large cohort of young women

Collins, L. C., Gelber, S., Marotti, J. D., White, S., Ruddy, K., Brachtel, E. F., Schapira, L., Come, S. E., Borges, V. F., Schedin, P., Warner, E., Wensley, T., Tamimi, R. M., Winer, E. P. & Partridge, A. H., May 29 2015, In : Oncologist. 20, 7, p. 713-718 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

Myoepithelial cell differentiation markers in ductal carcinoma in situ progression

Russell, T. D., Jindal, S., Agunbiade, S., Gao, D., Troxell, M., Borges, V. F. & Schedin, P., Nov 2015, In : American Journal of Pathology. 185, 11, p. 3076-3089 14 p.

Research output: Contribution to journalArticle

25 Scopus citations

Wound healing-like immune program facilitates postpartum mammary gland involution and tumor progression

Martinson, H. A., Jindal, S., Durand-Rougely, C., Borges, V. F. & Schedin, P., Apr 15 2015, In : International Journal of Cancer. 136, 8, p. 1803-1813 11 p.

Research output: Contribution to journalArticle

40 Scopus citations
2014

Cyclooxygenase-2-dependent lymphangiogenesis promotes nodal metastasis of postpartum breast cancer

Lyons, T. R., Borges, V. F., Betts, C. B., Guo, Q., Kapoor, P., Martinson, H. A., Jindal, S. & Schedin, P., Sep 2 2014, In : Journal of Clinical Investigation. 124, 9, p. 3901-3912 12 p.

Research output: Contribution to journalArticle

52 Scopus citations

Mammary gland involution as an immunotherapeutic target for postpartum breast cancer

Fornetti, J., Martinson, H. A., Betts, C. B., Lyons, T. R., Jindal, S., Guo, Q., Coussens, L. M., Borges, V. F. & Schedin, P., Jul 2014, In : Journal of Mammary Gland Biology and Neoplasia. 19, 2, p. 213-228 16 p.

Research output: Contribution to journalArticle

18 Scopus citations

Parity, lactation, and breast cancer subtypes in African American Women: Results from the AMBER Consortium

Palmer, J. R., Viscidi, E., Troester, M. A., Hong, C. C., Schedin, P., Bethea, T. N., Bandera, E. V., Borges, V., McKinnon, C., Haiman, C. A., Lunetta, K., Kolonel, L. N., Rosenberg, L., Olshan, A. F. & Ambrosone, C. B., Oct 1 2014, In : Journal of the National Cancer Institute. 106, 10, dju237.

Research output: Contribution to journalArticle

98 Scopus citations

Physiological COX-2 expression in breast epithelium associates with COX-2 levels in ductal carcinoma in situ and invasive breast cancer in young women

Fornetti, J., Jindal, S., Middleton, K. A., Borges, V. F. & Schedin, P., Apr 2014, In : American Journal of Pathology. 184, 4, p. 1219-1229 11 p.

Research output: Contribution to journalArticle

21 Scopus citations

Postpartum breast involution reveals regression of secretory lobules mediated by tissue-remodeling

Jindal, S., Gao, D., Bell, P., Albrektsen, G., Edgerton, S. M., Ambrosone, C. B., Thor, A. D., Borges, V. F. & Schedin, P., Mar 28 2014, In : Breast Cancer Research. 16, 2, R31.

Research output: Contribution to journalArticle

28 Scopus citations
2013

Collagen architecture in pregnancy-induced protection from breast cancer

Maller, O., Hansen, K. C., Lyons, T. R., Acerbi, I., Weaver, V. M., Prekeris, R., Tan, A. C. & Schedin, P., 2013, In : Journal of Cell Science. 126, 18, p. 4108-4120 13 p.

Research output: Contribution to journalArticle

62 Scopus citations

Genomic Signatures of Pregnancy-Associated Breast Cancer Epithelia and Stroma and their Regulation by Estrogens and Progesterone

Harvell, D. M. E., Kim, J., O'Brien, J., Tan, A. C., Borges, V. F., Schedin, P., Jacobsen, B. M. & Horwitz, K. B., 2013, In : Hormones and Cancer. 4, 3, p. 140-153 14 p.

Research output: Contribution to journalArticle

23 Scopus citations

Hypothesized role of pregnancy hormones on HER2+ breast tumor development

Cruz, G. I., Martínez, M. E., Natarajan, L., Wertheim, B. C., Gago-Dominguez, M., Bondy, M., Daneri-Navarro, A., Meza-Montenegro, M. M., Gutierrez-Millan, L. E., Brewster, A., Schedin, P., Komenaka, I. K., Castelao, J. E., Carracedo, A., Redondo, C. M. & Thompson, P. A., Jan 2013, In : Breast Cancer Research and Treatment. 137, 1, p. 237-246 10 p.

Research output: Contribution to journalArticle

14 Scopus citations

Mechanism and preclinical prevention of increased breast cancer risk caused by pregnancy

Haricharan, S., Dong, J., Hein, S., Reddy, J. P., Du, Z., Toneff, M., Holloway, K., Hilsenbeck, S. G., Huang, S., Atkinson, R., Woodward, W., Jindal, S., Borges, V. F., Gutierrez, C., Zhang, H., Schedin, P. J., Osborne, C. K., Tweardy, D. J. & Li, Y., Dec 31 2013, In : eLife. 2013, 2, e00996.

Research output: Contribution to journalArticle

23 Scopus citations

Postpartum diagnosis demonstrates a high risk for metastasis and merits an expanded definition of pregnancy-associated breast cancer

Callihan, E. B., Gao, D., Jindal, S., Lyons, T. R., Manthey, E., Edgerton, S., Urquhart, A., Schedin, P. & Borges, V. F., Apr 2013, In : Breast Cancer Research and Treatment. 138, 2, p. 549-559 11 p.

Research output: Contribution to journalArticle

84 Scopus citations

Rab40b regulates trafficking of MMP2 and MMP9 during invadopodia formation and invasion of breast cancer cells

Jacob, A., Jing, J., Lee, J., Schedin, P., Gilbert, S. M., Peden, A. A., Junutula, J. R. & Prekeris, R., 2013, In : Journal of Cell Science. 126, 20, p. 4647-4658 12 p.

Research output: Contribution to journalArticle

79 Scopus citations
2012

Alterations in mast cell frequency and relationship to angiogenesis in the rat mammary gland during windows of physiologic tissue remodeling

Ramirez, R. A., Lee, A., Schedin, P., Russell, J. S. & Masso-Welch, P. A., May 2012, In : Developmental Dynamics. 241, 5, p. 890-900 11 p.

Research output: Contribution to journalArticle

16 Scopus citations

Macrophages are crucial for epithelial cell death and adipocyte repopulation during mammary gland involution

O'Brien, J., Martinson, H., Durand-Rougely, C. & Schedin, P., Jan 15 2012, In : Development. 139, 2, p. 269-275 7 p.

Research output: Contribution to journalArticle

86 Scopus citations

Obesity and overfeeding affecting both tumor and systemic metabolism activates the progesterone receptor to contribute to postmenopausal breast cancer

Giles, E. D., Wellberg, E. A., Astling, D. P., Anderson, S. M., Thor, A. D., Jindal, S., Tan, A. C., Schedin, P. S. & MacLean, P. S., Dec 15 2012, In : Cancer Research. 72, 24, p. 6490-6501 12 p.

Research output: Contribution to journalArticle

34 Scopus citations

Rat mammary extracellular matrix composition and response to ibuprofen treatment during postpartum involution by differential GeLC-MS/MS analysis

OBrien, J. H., Vanderlinden, L. A., Schedin, P. J. & Hansen, K. C., Oct 5 2012, In : Journal of Proteome Research. 11, 10, p. 4894-4905 12 p.

Research output: Contribution to journalArticle

25 Scopus citations
2011

Clusterin induces matrix metalloproteinase-9 expression via ERK1/2 and PI3K/Akt/NF-κB pathways in monocytes/macrophages

Shim, Y. J., Kang, B. H., Jeon, H. S., Park, I. S., Lee, K. U., Lee, I. K., Park, G. H., Lee, K. M., Schedin, P. & Min, B. H., Oct 2011, In : Journal of Leukocyte Biology. 90, 4, p. 761-769 9 p.

Research output: Contribution to journalArticle

55 Scopus citations
236 Scopus citations

Non-steroidal anti-inflammatory drugs target the pro-tumorigenic extracellular matrix of the postpartum mammary gland

O'Brien, J., Hansen, K., Barkan, D., Green, J. & Schedin, P., 2011, In : International Journal of Developmental Biology. 55, 7-9, p. 745-755 11 p.

Research output: Contribution to journalArticle

27 Scopus citations

Postpartum mammary gland involution drives progression of ductal carcinoma in situ through collagen and COX-2

Lyons, T. R., O'Brien, J., Borges, V. F., Conklin, M. W., Keely, P. J., Eliceiri, K. W., Marusyk, A., Tan, A. C. & Schedin, P., Sep 2011, In : Nature medicine. 17, 9, p. 1109-1116 8 p.

Research output: Contribution to journalArticle

203 Scopus citations
2010

Alternatively activated macrophages and collagen remodeling characterize the postpartum involuting mammary gland across species

O'Brien, J., Lyons, T., Monks, J., Lucia, M. S., Wilson, R. S., Hines, L., Man, Y. G., Borges, V. & Schedin, P., Mar 2010, In : American Journal of Pathology. 176, 3, p. 1241-1255 15 p.

Research output: Contribution to journalArticle

143 Scopus citations

A surprising link between the energetics of ovariectomy-induced weight gain and mammary tumor progression in obese rats

MacLean, P. S., Giles, E. D., Johnson, G. C., McDaniel, S. M., Fleming-Elder, B. K., Gilman, K. A., Andrianakos, A. G., Jackman, M. R., Shroyer, K. R. & Schedin, P. J., Apr 2010, In : Obesity. 18, 4, p. 696-703 8 p.

Research output: Contribution to journalArticle

16 Scopus citations

Benign mammary epithelial cells enhance the transformed phenotype of human breast cancer cells

Poczobutt, J. M., Tentler, J., Lu, X., Schedin, P. J. & Gutierrez-Hartmann, A., Jul 16 2010, In : BMC cancer. 10, 373.

Research output: Contribution to journalArticle

11 Scopus citations