Michael Cohen

Associate Professor

  • 2744 Citations
  • 23 h-Index
20022019
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Fingerprint Dive into the research topics where Michael Cohen is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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Adenosine Diphosphate Medicine & Life Sciences
NAD Medicine & Life Sciences
Phosphorylation Medicine & Life Sciences
Ribosomal Protein S6 Kinases Medicine & Life Sciences
Poly(ADP-ribose) Polymerases Medicine & Life Sciences
90-kDa Ribosomal Protein S6 Kinases Medicine & Life Sciences
Phosphotransferases Medicine & Life Sciences
Adenosine Diphosphate Ribose Medicine & Life Sciences

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Projects 2014 2019

Adenosine Diphosphate
Neurons
Long-Term Memory
Proteins
NAD

Research Output 2002 2019

Correction to: Structural basis for potency and promiscuity in poly(ADP-ribose) polymerase (PARP) and tankyrase inhibitors (Journal of Medicinal Chemistry (2017) 60: 4 (1262-1271) DOI: 10.1021/acs.jmedchem.6b00990)

Thorsell, A. G., Ekblad, T., Karlberg, T., Löw, M., Pinto, A. F., Trésaugues, L., Moche, M., Cohen, M. & Schüler, H., Jun 27 2019, In : Journal of Medicinal Chemistry. 62, 12, 1 p.

Research output: Contribution to journalComment/debate

Tankyrases
Pharmaceutical Chemistry
Inhibitory Concentration 50
Poly(ADP-ribose) Polymerase Inhibitors
niraparib

Fondation Leducq Transatlantic Network of Excellence Targeting Mitochondria to Treat Heart Disease

Murphy, E., Bernardi, P., Cohen, M., Di Lisa, F., Forte, M., Molkentin, J. D. & Ovize, M., Apr 26 2019, In : Circulation research. 124, 9, p. 1294-1296 3 p.

Research output: Contribution to journalComment/debate

Open Access
Heart Diseases
Reactive Oxygen Species
Mitochondria
Heart Failure
Phosphorylation
1 Citation (Scopus)

Reversible ADP-ribosylation of RNA

Munnur, D., Bartlett, E., Mikolčević, P., Kirby, I. T., Matthias Rack, J. G., Mikoč, A., Cohen, M. & Ahel, I., Jun 20 2019, In : Nucleic acids research. 47, 11, p. 5658-5669 12 p.

Research output: Contribution to journalArticle

Open Access
Adenosine Diphosphate
RNA
ADP-ribosylarginine hydrolase
NAD
ADP Ribose Transferases
4 Citations (Scopus)

Small-Molecule Inhibitors of PARPs: From Tools for Investigating ADP-Ribosylation to Therapeutics

Kirby, I. T. & Cohen, M., Jan 1 2019, In : Current Topics in Microbiology and Immunology. 420, p. 211-231 21 p.

Research output: Contribution to journalArticle

Adenosine Diphosphate
Polypharmacology
Poly(ADP-ribose) Polymerases
History
Therapeutics
5 Citations (Scopus)

ADP-ribosyl-binding and hydrolase activities of the alphavirus nsP3 macrodomain are critical for initiation of virus replication

Abraham, R., Hauer, D., McPherson, R. L., Utt, A., Kirby, I. T., Cohen, M., Merits, A., Leung, A. K. L. & Griffin, D. E., Oct 30 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 44, p. E10457-E10466

Research output: Contribution to journalArticle

Adenosine Diphosphate Ribose
Alphavirus
Hydrolases
Chikungunya virus
Virus Replication