Michael Cohen

Associate Professor

  • 2678 Citations
  • 23 h-Index
20022019
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Projects 2014 2019

Adenosine Diphosphate
Neurons
Long-Term Memory
Proteins
NAD

Research Output 2002 2019

  • 2678 Citations
  • 23 h-Index
  • 42 Article
  • 3 Chapter
  • 1 Short survey
  • 1 Review article
4 Citations (Scopus)

Small-Molecule Inhibitors of PARPs: From Tools for Investigating ADP-Ribosylation to Therapeutics

Kirby, I. T. & Cohen, M., Jan 1 2019, In : Current Topics in Microbiology and Immunology. 420, p. 211-231 21 p.

Research output: Contribution to journalArticle

Adenosine Diphosphate
Polypharmacology
Poly(ADP-ribose) Polymerases
History
Therapeutics
3 Citations (Scopus)

ADP-ribosyl-binding and hydrolase activities of the alphavirus nsP3 macrodomain are critical for initiation of virus replication

Abraham, R., Hauer, D., McPherson, R. L., Utt, A., Kirby, I. T., Cohen, M., Merits, A., Leung, A. K. L. & Griffin, D. E., Oct 30 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 44, p. E10457-E10466

Research output: Contribution to journalArticle

Adenosine Diphosphate Ribose
Alphavirus
Hydrolases
Chikungunya virus
Virus Replication
3 Citations (Scopus)

A Potent and Selective PARP11 Inhibitor Suggests Coupling between Cellular Localization and Catalytic Activity

Kirby, I. T., Kojic, A., Arnold, M. R., Thorsell, A. G., Karlberg, T., Vermehren-Schmaedick, A., Sreenivasan, R., Schultz, C., Schüler, H. & Cohen, M., Dec 20 2018, In : Cell Chemical Biology. 25, 12, p. 1547-1553.e12

Research output: Contribution to journalArticle

Adenosine Diphosphate
Catalyst activity
Nuclear Envelope
Poly(ADP-ribose) Polymerases
Availability
1 Citation (Scopus)

A simple, sensitive, and generalizable plate assay for screening PARP inhibitors

Kirby, I. T., Morgan, R. K. & Cohen, M., Jan 1 2018, Methods in Molecular Biology. Humana Press Inc., p. 245-252 8 p. (Methods in Molecular Biology; vol. 1813).

Research output: Chapter in Book/Report/Conference proceedingChapter

Enzymes
ADP Ribose Transferases
Unfolded Protein Response
Poly(ADP-ribose) Polymerases
Post Translational Protein Processing
1 Citation (Scopus)

Combining Chemical Genetics with Proximity-Dependent Labeling Reveals Cellular Targets of Poly(ADP-ribose) Polymerase 14 (PARP14)

Carter-O'Connell, I., Vermehren-Schmaedick, A., Jin, H., Morgan, R. K., David, L. & Cohen, M., Oct 19 2018, In : ACS Chemical Biology. 13, 10, p. 2841-2848 8 p.

Research output: Contribution to journalArticle

Poly(ADP-ribose) Polymerases
Labeling
Adenosine Diphosphate
NAD
Proteins