Martina Ralle

Assistant Professor

Assistant Professor, Molecular & Medical Genetics

Emailrallem@ohsu.edu

1759 Citations
23 h-Index

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4 Similar Profiles

Copper Medicine & Life Sciences

Metals Medicine & Life Sciences

Hepatolenticular Degeneration Medicine & Life Sciences

Azurin Chemical Compounds

Mixed Function Oxygenases Chemical Compounds

X-Ray Absorption Spectroscopy Medicine & Life Sciences

Ligands Chemical Compounds

Menkes Kinky Hair Syndrome Medicine & Life Sciences

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The Role of Hepatic Copper Accumulation in Wilson Disease

Ralle, M.

National Institutes of Health

3/1/10 → 2/29/16

Project: Research project

Hepatolenticular Degeneration

Copper

Liver

Oxidation-Reduction

Necrosis

ICP-MS to Measure Elemental Concentrations

Ralle, M.

National Institutes of Health

5/7/09 → 5/6/10

Project: Research project

Inductively coupled plasma

Mass spectrometers

Metals

Biological materials

Metal ions

Copper entry into human cells

David, L., Ralle, M., Blackburn, N., Enns, C., Bjorkman, P., Hubbard, A., Kaplan, J., Unger, V., Lutsenko, S. & Enns, C.

National Institutes of Health

12/1/02 → 8/31/15

Project: Research project

Metal ions

Copper

Transferrin Receptors

Homeostasis

Proteins

Research Output 1992 2019

1759 Citations
23 h-Index
53 Article
1 Conference contribution

Localization of the Locus Coeruleus in the Mouse Brain

Schmidt, K., Bari, B., Ralle, M., Washington-Hughes, C., Muchenditsi, A., Maxey, E. & Lutsenko, S., Mar 7 2019, In : Journal of visualized experiments : JoVE. 145

Research output: Contribution to journal › Article

Locus Coeruleus

Brain

Metals

Metal testing

Norepinephrine

1 Citation (Scopus)

Altered zinc balance in the Atp7b^−/− mouse reveals a mechanism of copper toxicity in Wilson disease

Meacham, K. A., Cortés, M. P., Wiggins, E. M., Maass, A., Latorre, M., Ralle, M. & Burkhead, J. L., Nov 1 2018, In : Metallomics. 10, 11, p. 1595-1606 12 p.

Research output: Contribution to journal › Article

Hepatolenticular Degeneration

Toxicity

Zinc

Copper

Liver

5 Citations (Scopus)

ATP7A and ATP7B copper transporters have distinct functions in the regulation of neuronal dopamine--hydroxylase

Schmidt, K., Ralle, M., Schaffer, T., Jayakanthan, S., Bari, B., Muchenditsi, A. & Lutsenko, S., Jan 1 2018, In : Journal of Biological Chemistry. 293, 52, p. 20085-20098 14 p.

Research output: Contribution to journal › Article

Mixed Function Oxygenases

Copper

Dopamine

Catecholamines

Cultured Cells

Cerebrospinal Fluid-Directed rAAV9-rsATP7A Plus Subcutaneous Copper Histidinate Advance Survival and Outcomes in a Menkes Disease Mouse Model

Haddad, M. R., Choi, E. Y., Zerfas, P. M., Yi, L., Martinelli, D., Sullivan, P., Goldstein, D. S., Centeno, J. A., Brinster, L. R., Ralle, M. & Kaler, S. G., Sep 21 2018, In : Molecular Therapy - Methods and Clinical Development. 10, p. 165-178 14 p.

Research output: Contribution to journal › Article

Menkes Kinky Hair Syndrome

Dependovirus

Cerebrospinal Fluid

Copper

Survival

2 Citations (Scopus)

Copper-dependent amino oxidase 3 governs selection of metabolic fuels in adipocytes

Yang, H., Ralle, M., Wolfgang, M. J., Dhawan, N., Burkhead, J. L., Rodriguez, S., Kaplan, J. H., Wong, G. W., Haughey, N. & Lutsenko, S., Sep 1 2018, In : PLoS Biology. 16, 9, e2006519.

Research output: Contribution to journal › Article

Amine Oxidase (Copper-Containing)

adipocytes

amines

Adipocytes

Copper