Markus Grompe

Professor

  • 24083 Citations
  • 73 h-Index
1984 …2021
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  • 19 Similar Profiles
Fanconi Anemia Medicine & Life Sciences
Hepatocytes Medicine & Life Sciences
Liver Medicine & Life Sciences
Tyrosinemias Medicine & Life Sciences
Genes Medicine & Life Sciences
Stem Cells Medicine & Life Sciences
Genetic Therapy Medicine & Life Sciences
Hematopoietic Stem Cells Medicine & Life Sciences

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Projects 1991 2021

Liver Cancer Risk with rAAV Gene Therapy

Grompe, M. & Russell, D.

National Institutes of Health

4/1/153/31/20

Project: Research project

Dependovirus
Liver Neoplasms
Genetic Therapy
Hepatocellular Carcinoma
Liver
Dependovirus
Capsid
MicroRNAs
Epithelium
Somatostatin-Secreting Cells
Bile Ducts
Hepatocytes
Liver
Epigenomics
Liver Diseases

MOLECULAR GENETICS OF FANCONI ANEMIA

Olson, S., Bagby, G., Moses, R., Grompe, M., D'Andrea, A. D., Postlethwait, J. H., D'Andrea, A. D. & Fleming, W.

National Institutes of Health

7/1/945/31/21

Project: Research project

Fanconi Anemia
Cytogenetics
Genes
Fanconi Anemia Complementation Group Proteins
Bone Marrow

Novel Sources of Transplantable Beta-cell Replacements

Grompe, M., Streeter, P., Kay, M. & Kaestner, K. H.

National Institutes of Health

9/15/106/30/16

Project: Research project

Pluripotent Stem Cells
Endoderm
Type 1 Diabetes Mellitus
Liver
Epigenomics

Research Output 1984 2019

  • 24083 Citations
  • 73 h-Index
  • 250 Article
  • 12 Conference contribution
  • 8 Chapter
  • 1 Review article
3 Citations (Scopus)

Diabetes relief in mice by glucose-sensing insulin-secreting human α-cells

Furuyama, K., Chera, S., van Gurp, L., Oropeza, D., Ghila, L., Damond, N., Vethe, H., Paulo, J. A., Joosten, A. M., Berney, T., Bosco, D., Dorrell, C., Grompe, M., Ræder, H., Roep, B. O., Thorel, F. & Herrera, P. L., Mar 7 2019, In : Nature. 567, 7746, p. 43-48 6 p.

Research output: Contribution to journalArticle

Insulin-Secreting Cells
Glucose
Insulin
Pancreatic Polypeptide-Secreting Cells
Somatostatin-Secreting Cells

Combination therapy with atorvastatin and celecoxib delays tumor formation in a Fanconi anemia mouse model

Zhang, Q-S., Deater, M., Phan, N., Marcogliese, A., Major, A., Guinan, E. C. & Grompe, M., Jan 1 2018, (Accepted/In press) In : Pediatric Blood and Cancer.

Research output: Contribution to journalArticle

Celecoxib
Fanconi Anemia
Neoplasms
Therapeutics
Pharmaceutical Preparations
3 Citations (Scopus)

Comprehensive human cell-type methylation atlas reveals origins of circulating cell-free DNA in health and disease

Moss, J., Magenheim, J., Neiman, D., Zemmour, H., Loyfer, N., Korach, A., Samet, Y., Maoz, M., Druid, H., Arner, P., Fu, K. Y., Kiss, E., Spalding, K. L., Landesberg, G., Zick, A., Grinshpun, A., Shapiro, A. M. J., Grompe, M., Wittenberg, A. D., Glaser, B. & 3 othersShemer, R., Kaplan, T. & Dor, Y., Dec 1 2018, In : Nature Communications. 9, 1, 5068.

Research output: Contribution to journalArticle

methylation
Methylation
Atlases
health
deoxyribonucleic acid
3 Citations (Scopus)

Inflammatory Cytokine TNFα Promotes the Long-Term Expansion of Primary Hepatocytes in 3D Culture

Peng, W. C., Logan, C. Y., Fish, M., Anbarchian, T., Aguisanda, F., Álvarez-Varela, A., Wu, P., Jin, Y., Zhu, J., Li, B., Grompe, M., Wang, B. & Nusse, R., Nov 29 2018, In : Cell. 175, 6, p. 1607-1619.e15

Research output: Contribution to journalArticle

Hepatocytes
Cytokines
Liver
Organoids
RNA Sequence Analysis
4 Citations (Scopus)

Long-Term Correction of Diabetes in Mice by In Vivo Reprogramming of Pancreatic Ducts

Wang, Y., Dorrell, C., Naugler, W. S., Heskett, M., Spellman, P., Li, B., Galivo, F., Haft, A., Wakefield, L. & Grompe, M., Jan 1 2018, (Accepted/In press) In : Molecular Therapy.

Research output: Contribution to journalArticle

Pancreatic Ducts
Cell- and Tissue-Based Therapy
Type 1 Diabetes Mellitus
Endoscopic Retrograde Cholangiopancreatography
Essential Genes