Projects per year
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- 19 Similar Profiles
Fanconi Anemia
Medicine & Life Sciences
Hepatocytes
Medicine & Life Sciences
Liver
Medicine & Life Sciences
Tyrosinemias
Medicine & Life Sciences
Genes
Medicine & Life Sciences
Stem Cells
Medicine & Life Sciences
Genetic Therapy
Medicine & Life Sciences
Hematopoietic Stem Cells
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 1991 2021
Liver Cancer Risk with rAAV Gene Therapy
Grompe, M. & Russell, D.
4/1/15 → 3/31/20
Project: Research project
Dependovirus
Liver Neoplasms
Genetic Therapy
Hepatocellular Carcinoma
Liver
In vivo targeting of diabetes-relevant human cell types with rAAV vectors
Grompe, M., Nakai, H. & Kay, M.
9/30/14 → 6/30/19
Project: Research project
Dependovirus
Capsid
MicroRNAs
Epithelium
Somatostatin-Secreting Cells
Bile Ducts
Hepatocytes
Liver
Epigenomics
Liver Diseases
MOLECULAR GENETICS OF FANCONI ANEMIA
Olson, S., Bagby, G., Moses, R., Grompe, M., D'Andrea, A. D., Postlethwait, J. H., D'Andrea, A. D. & Fleming, W.
7/1/94 → 5/31/21
Project: Research project
Fanconi Anemia
Cytogenetics
Genes
Fanconi Anemia Complementation Group Proteins
Bone Marrow
Novel Sources of Transplantable Beta-cell Replacements
Grompe, M., Streeter, P., Kay, M. & Kaestner, K. H.
9/15/10 → 6/30/16
Project: Research project
Pluripotent Stem Cells
Endoderm
Type 1 Diabetes Mellitus
Liver
Epigenomics
Research Output 1984 2019
3
Citations
(Scopus)
Diabetes relief in mice by glucose-sensing insulin-secreting human α-cells
Furuyama, K., Chera, S., van Gurp, L., Oropeza, D., Ghila, L., Damond, N., Vethe, H., Paulo, J. A., Joosten, A. M., Berney, T., Bosco, D., Dorrell, C., Grompe, M., Ræder, H., Roep, B. O., Thorel, F. & Herrera, P. L., Mar 7 2019, In : Nature. 567, 7746, p. 43-48 6 p.Research output: Contribution to journal › Article
Insulin-Secreting Cells
Glucose
Insulin
Pancreatic Polypeptide-Secreting Cells
Somatostatin-Secreting Cells
Combination therapy with atorvastatin and celecoxib delays tumor formation in a Fanconi anemia mouse model
Zhang, Q-S., Deater, M., Phan, N., Marcogliese, A., Major, A., Guinan, E. C. & Grompe, M., Jan 1 2018, (Accepted/In press) In : Pediatric Blood and Cancer.Research output: Contribution to journal › Article
Celecoxib
Fanconi Anemia
Neoplasms
Therapeutics
Pharmaceutical Preparations
3
Citations
(Scopus)
Comprehensive human cell-type methylation atlas reveals origins of circulating cell-free DNA in health and disease
Moss, J., Magenheim, J., Neiman, D., Zemmour, H., Loyfer, N., Korach, A., Samet, Y., Maoz, M., Druid, H., Arner, P., Fu, K. Y., Kiss, E., Spalding, K. L., Landesberg, G., Zick, A., Grinshpun, A., Shapiro, A. M. J., Grompe, M., Wittenberg, A. D., Glaser, B. & 3 others, Dec 1 2018, In : Nature Communications. 9, 1, 5068.Research output: Contribution to journal › Article
methylation
Methylation
Atlases
health
deoxyribonucleic acid
3
Citations
(Scopus)
Inflammatory Cytokine TNFα Promotes the Long-Term Expansion of Primary Hepatocytes in 3D Culture
Peng, W. C., Logan, C. Y., Fish, M., Anbarchian, T., Aguisanda, F., Álvarez-Varela, A., Wu, P., Jin, Y., Zhu, J., Li, B., Grompe, M., Wang, B. & Nusse, R., Nov 29 2018, In : Cell. 175, 6, p. 1607-1619.e15Research output: Contribution to journal › Article
Hepatocytes
Cytokines
Liver
Organoids
RNA Sequence Analysis
4
Citations
(Scopus)
Long-Term Correction of Diabetes in Mice by In Vivo Reprogramming of Pancreatic Ducts
Wang, Y., Dorrell, C., Naugler, W. S., Heskett, M., Spellman, P., Li, B., Galivo, F., Haft, A., Wakefield, L. & Grompe, M., Jan 1 2018, (Accepted/In press) In : Molecular Therapy.Research output: Contribution to journal › Article
Pancreatic Ducts
Cell- and Tissue-Based Therapy
Type 1 Diabetes Mellitus
Endoscopic Retrograde Cholangiopancreatography
Essential Genes