Markus Grompe

Professor

  • 23214 Citations
  • 72 h-Index
1984 …2021
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  • 21 Similar Profiles
Fanconi Anemia Medicine & Life Sciences
Hepatocytes Medicine & Life Sciences
Liver Medicine & Life Sciences
Tyrosinemias Medicine & Life Sciences
Genes Medicine & Life Sciences
Stem Cells Medicine & Life Sciences
Genetic Therapy Medicine & Life Sciences
Hematopoietic Stem Cells Medicine & Life Sciences

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Projects 1991 2021

Liver Cancer Risk with rAAV Gene Therapy

Grompe, M. & Russell, D.

National Institutes of Health

4/1/153/31/20

Project: Research projectResearch Project

Dependovirus
Liver Neoplasms
Genetic Therapy
Hepatocellular Carcinoma
Liver

In vivo targeting of diabetes-relevant human cell types with rAAV vectors

Grompe, M., Nakai, H. & Kay, M.

National Institutes of Health

9/30/146/30/19

Project: Research projectHigh Impact Research and Research Infrastructure Cooperative Agreement Programs—Multi-Yr Funding

Dependovirus
Capsid
MicroRNAs
Epithelium
Somatostatin-Secreting Cells

Mechanisms of Bile Duct Morphogenesis

Grompe, M.

National Institutes of Health

7/1/091/31/21

Project: Research projectResearch Project

Bile Ducts
Hepatocytes
Liver
Epigenomics
Liver Diseases

MOLECULAR GENETICS OF FANCONI ANEMIA

Olson, S., Bagby, G., Moses, R., Grompe, M., D'Andrea, A. D., Postlethwait, J. H., D'Andrea, A. D. & Fleming, W.

National Institutes of Health

7/1/945/31/21

Project: Research projectResearch Program Projects

Fanconi Anemia
Cytogenetics
Genes
Fanconi Anemia Complementation Group Proteins
Bone Marrow

Novel Sources of Transplantable Beta-cell Replacements

Grompe, M., Streeter, P., Kay, M. & Kaestner, K. H.

National Institutes of Health

9/15/106/30/16

Project: Research projectResearch Project--Cooperative Agreements

Pluripotent Stem Cells
Endoderm
Type 1 Diabetes Mellitus
Liver
Epigenomics

Research Output 1984 2018

  • 23214 Citations
  • 72 h-Index
  • 245 Article
  • 12 Conference contribution
  • 8 Chapter
  • 1 Review article

Combination therapy with atorvastatin and celecoxib delays tumor formation in a Fanconi anemia mouse model

Zhang, Q-S., Deater, M., Phan, N., Marcogliese, A., Major, A., Guinan, E. C. & Grompe, M., Jan 1 2018, (Accepted/In press) In : Pediatric Blood and Cancer.

Research output: Contribution to journalArticle

Celecoxib
Fanconi Anemia
Neoplasms
Therapeutics
Pharmaceutical Preparations
2 Citations

Long-Term Correction of Diabetes in Mice by In Vivo Reprogramming of Pancreatic Ducts

Wang, Y., Dorrell, C., Naugler, W. E., Heskett, M., Spellman, P., Li, B., Galivo, F., Haft, A., Wakefield, L. & Grompe, M., Jan 1 2018, (Accepted/In press) In : Molecular Therapy.

Research output: Contribution to journalArticle

Pancreatic Ducts
Insulin-Secreting Cells
Cell- and Tissue-Based Therapy
Type 1 Diabetes Mellitus
Endoscopic Retrograde Cholangiopancreatography
18 Citations

A Drug Screen using Human iPSC-Derived Hepatocyte-like Cells Reveals Cardiac Glycosides as a Potential Treatment for Hypercholesterolemia

Cayo, M. A., Mallanna, S. K., Di Furio, F., Jing, R., Tolliver, L. B., Bures, M., Urick, A., Noto, F. K., Pashos, E. E., Greseth, M. D., Czarnecki, M., Traktman, P., Yang, W., Morrisey, E. E., Grompe, M., Rader, D. J. & Duncan, S. A., Apr 6 2017, In : Cell Stem Cell. 20, 4, p. 478-489.e5

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Cardiac Glycosides
Hypercholesterolemia
Hepatocytes
Apolipoproteins B
9 Citations

Adult Mouse Liver Contains Two Distinct Populations of Cholangiocytes

Li, B., Dorrell, C., Canaday, P. S., Pelz, C., Haft, A., Finegold, M. & Grompe, M., 2017, (Accepted/In press) In : Stem Cell Reports.

Research output: Contribution to journalArticle

Liver
Ducts
Organoids
Population
Gene expression
9 Citations

Bioengineered AAV Capsids with Combined High Human Liver Transduction In Vivo and Unique Humoral Seroreactivity

Paulk, N. K., Pekrun, K., Zhu, E., Nygaard, S., Li, B., Xu, J., Chu, K., Leborgne, C., Dane, A. P., Haft, A., Zhang, Y., Zhang, F., Morton, C., Valentine, M. B., Davidoff, A. M., Nathwani, A. C., Mingozzi, F., Grompe, M., Alexander, I. E., Lisowski, L. & 1 othersKay, M. A., 2017, (Accepted/In press) In : Molecular Therapy.

Research output: Contribution to journalArticle

Capsid
Liver
Hepatocytes
Genetic Therapy
Libraries