Projects per year
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- 21 Similar Profiles
Fanconi Anemia
Medicine & Life Sciences
Hepatocytes
Medicine & Life Sciences
Liver
Medicine & Life Sciences
Tyrosinemias
Medicine & Life Sciences
Genes
Medicine & Life Sciences
Stem Cells
Medicine & Life Sciences
Genetic Therapy
Medicine & Life Sciences
Hematopoietic Stem Cells
Medicine & Life Sciences
Network
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Projects 1991 2021
Liver Cancer Risk with rAAV Gene Therapy
Grompe, M. & Russell, D.
4/1/15 → 3/31/20
Project: Research project › Research Project
Dependovirus
Liver Neoplasms
Genetic Therapy
Hepatocellular Carcinoma
Liver
In vivo targeting of diabetes-relevant human cell types with rAAV vectors
Grompe, M., Nakai, H. & Kay, M.
9/30/14 → 6/30/19
Project: Research project › High Impact Research and Research Infrastructure Cooperative Agreement Programs—Multi-Yr Funding
Dependovirus
Capsid
MicroRNAs
Epithelium
Somatostatin-Secreting Cells
Bile Ducts
Hepatocytes
Liver
Epigenomics
Liver Diseases
MOLECULAR GENETICS OF FANCONI ANEMIA
Olson, S., Bagby, G., Moses, R., Grompe, M., D'Andrea, A. D., Postlethwait, J. H., D'Andrea, A. D. & Fleming, W.
7/1/94 → 5/31/21
Project: Research project › Research Program Projects
Fanconi Anemia
Cytogenetics
Genes
Fanconi Anemia Complementation Group Proteins
Bone Marrow
Novel Sources of Transplantable Beta-cell Replacements
Grompe, M., Streeter, P., Kay, M. & Kaestner, K. H.
9/15/10 → 6/30/16
Project: Research project › Research Project--Cooperative Agreements
Pluripotent Stem Cells
Endoderm
Type 1 Diabetes Mellitus
Liver
Epigenomics
Research Output 1984 2018
Combination therapy with atorvastatin and celecoxib delays tumor formation in a Fanconi anemia mouse model
Zhang, Q-S., Deater, M., Phan, N., Marcogliese, A., Major, A., Guinan, E. C. & Grompe, M., Jan 1 2018, (Accepted/In press) In : Pediatric Blood and Cancer.Research output: Contribution to journal › Article
Celecoxib
Fanconi Anemia
Neoplasms
Therapeutics
Pharmaceutical Preparations
2
Citations
Long-Term Correction of Diabetes in Mice by In Vivo Reprogramming of Pancreatic Ducts
Wang, Y., Dorrell, C., Naugler, W. E., Heskett, M., Spellman, P., Li, B., Galivo, F., Haft, A., Wakefield, L. & Grompe, M., Jan 1 2018, (Accepted/In press) In : Molecular Therapy.Research output: Contribution to journal › Article
Pancreatic Ducts
Insulin-Secreting Cells
Cell- and Tissue-Based Therapy
Type 1 Diabetes Mellitus
Endoscopic Retrograde Cholangiopancreatography
18
Citations
A Drug Screen using Human iPSC-Derived Hepatocyte-like Cells Reveals Cardiac Glycosides as a Potential Treatment for Hypercholesterolemia
Cayo, M. A., Mallanna, S. K., Di Furio, F., Jing, R., Tolliver, L. B., Bures, M., Urick, A., Noto, F. K., Pashos, E. E., Greseth, M. D., Czarnecki, M., Traktman, P., Yang, W., Morrisey, E. E., Grompe, M., Rader, D. J. & Duncan, S. A., Apr 6 2017, In : Cell Stem Cell. 20, 4, p. 478-489.e5Research output: Contribution to journal › Article
Induced Pluripotent Stem Cells
Cardiac Glycosides
Hypercholesterolemia
Hepatocytes
Apolipoproteins B
9
Citations
Adult Mouse Liver Contains Two Distinct Populations of Cholangiocytes
Li, B., Dorrell, C., Canaday, P. S., Pelz, C., Haft, A., Finegold, M. & Grompe, M., 2017, (Accepted/In press) In : Stem Cell Reports.Research output: Contribution to journal › Article
Liver
Ducts
Organoids
Population
Gene expression
9
Citations
Bioengineered AAV Capsids with Combined High Human Liver Transduction In Vivo and Unique Humoral Seroreactivity
Paulk, N. K., Pekrun, K., Zhu, E., Nygaard, S., Li, B., Xu, J., Chu, K., Leborgne, C., Dane, A. P., Haft, A., Zhang, Y., Zhang, F., Morton, C., Valentine, M. B., Davidoff, A. M., Nathwani, A. C., Mingozzi, F., Grompe, M., Alexander, I. E., Lisowski, L. & 1 others, 2017, (Accepted/In press) In : Molecular Therapy.Research output: Contribution to journal › Article
Capsid
Liver
Hepatocytes
Genetic Therapy
Libraries