Leslie Myatt

Professor

  • 10546 Citations
  • 55 h-Index
1975 …2020

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Research Output

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2019

Activation of prostaglandin EP4 receptor attenuates the induction of cyclooxygenase-2 expression by EP2 receptor activation in human amnion fibroblasts: implications for parturition

Lu, J. W., Wang, W. S., Zhou, Q., Gan, X. W., Myatt, L. & Sun, K., Jul 1 2019, In : FASEB Journal. 33, 7, p. 8148-8160 13 p.

Research output: Contribution to journalArticle

3 Scopus citations
5 Scopus citations

Risk of Ischemic Placental Disease in Relation to Family History of Preeclampsia

Ananth, C. V., Jablonski, K., Myatt, L., Roberts, J. M., Tita, A. T. N., Leveno, K. J., Reddy, U. M., Varner, M. W., Thorp, J. M., Mercer, B. M., Peaceman, A. M., Ramin, S. M., Carpenter, M. W., Samuels, P., Sciscione, A., Tolosa, J. E., Saade, G. & Sorokin, Y., Jan 1 2019, In : American journal of perinatology. 36, 6, p. 624-631 8 p.

Research output: Contribution to journalArticle

2 Scopus citations
2018

Adverse Maternal and Neonatal Outcomes in Indicated Compared with Spontaneous Preterm Birth in Healthy Nulliparas: A Secondary Analysis of a Randomized Trial

Tita, A. T., Doherty, L., Roberts, J. M., Myatt, L., Leveno, K. J., Varner, M. W., Wapner, R. J., Thorp, J. M., Mercer, B. M., Peaceman, A., Ramin, S. M., Carpenter, M. W., Iams, J., Sciscione, A., Harper, M., Tolosa, J. E., Saade, G. R. & Sorokin, Y., Jun 1 2018, In : American journal of perinatology. 35, 7, p. 624-631 8 p.

Research output: Contribution to journalArticle

COLLECT, a collaborative database for pregnancy and placental research studies worldwide

the Global Pregnancy Collaboration (CoLab), Jan 1 2018, (Accepted/In press) In : BJOG: An International Journal of Obstetrics and Gynaecology.

Research output: Contribution to journalArticle

5 Scopus citations

Incidence of early-onset sepsis in infants born to women with clinical chorioamnionitis

Randis, T. M., Rice, M. M., Myatt, L., Tita, A. T. N., Leveno, K. J., Reddy, U. M., Varner, M. W., Thorp, J. M., Mercer, B. M., Dinsmoor, M. J., Ramin, S. M., Carpenter, M. W., Samuels, P., Sciscione, A., Tolosa, J., Saade, G. & Sorokin, Y., May 23 2018, (Accepted/In press) In : Journal of Perinatal Medicine.

Research output: Contribution to journalArticle

12 Scopus citations

Melatonin Improves Mitochondrial Respiration in Syncytiotrophoblasts From Placentas of Obese Women

Ireland, K. E., Maloyan, A. & Myatt, L., Jan 1 2018, In : Reproductive Sciences. 25, 1, p. 120-130 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

Tropomyosin Receptor Kinase B Agonist, 7,8-Dihydroxyflavone, Improves Mitochondrial Respiration in Placentas From Obese Women

Prince, C. S., Maloyan, A. & Myatt, L., Mar 1 2018, In : Reproductive Sciences. 25, 3, p. 452-462 11 p.

Research output: Contribution to journalArticle

2 Scopus citations
2017

AKAP95-mediated nuclear anchoring of PKA mediates cortisol-induced PTGS2 expression in human amnion fibroblasts

Lu, J., Wang, W., Mi, Y., Zhang, C., Ying, H., Wang, L., Wang, Y., Myatt, L. & Sun, K., Nov 21 2017, In : Science signaling. 10, 506, eaac6160.

Research output: Contribution to journalArticle

7 Scopus citations

Alterations in the placental methylome with maternal obesity and evidence for metabolic regulation

Mitsuya, K., Parker, A. N., Liu, L., Ruan, J., Vissers, M. C. M. & Myatt, L., Oct 2017, In : PloS one. 12, 10, e0186115.

Research output: Contribution to journalArticle

20 Scopus citations

Autophagic degradation of collagen 1A1 by cortisol in human amnion fibroblasts

Mi, Y., Wang, W., Zhang, C., Liu, C., Lu, J., Li, W., Zuo, R., Myatt, L. & Sun, K., Apr 1 2017, In : Endocrinology. 158, 4, p. 1005-1014 10 p.

Research output: Contribution to journalArticle

16 Scopus citations

Availability of COLLECT, a database for pregnancy and placental research studies worldwide

Global Pregnancy Collaboration (CoLab), Sep 1 2017, In : Placenta. 57, p. 223-224 2 p.

Research output: Contribution to journalArticle

7 Scopus citations

IFPA meeting 2016 workshop report II: Placental imaging, placenta and development of other organs, sexual dimorphism in placental function and trophoblast cell lines

Adibi, J., Burton, G. J., Clifton, V., Collins, S., Frias, A. E., Gierman, L., Grigsby, P., Jones, H., Lee, C., Maloyan, A., Markert, U. R., Morales-Prieto, D. M., Murthi, P., Myatt, L., Pollheimer, J., Roberts, V., Robinson, W., Salafia, C., Schabel, M., Shah, D. & 4 others, Sled, J., Vaillancourt, C., Weber, M. & O'Tierney-Ginn, P. F., Dec 2017, In : Placenta. 60, p. S10-S14

Research output: Contribution to journalArticle

9 Scopus citations

Maternal obesity alters brain derived neurotrophic factor (BDNF) signaling in the placenta in a sexually dimorphic manner

Prince, C. S., Maloyan, A. & Myatt, L., Jan 1 2017, In : Placenta. 49, p. 55-63 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Novel thoughts on preterm birth research proceedings of the 13th annual preterm birth international collaborative (PREBIC) meeting

Gyamfi-Bannerman, C., Menon, R., Bonney, E. A., Dolan, S. M., Johnson, M., Lamont, R. F., Mesiano, S., Murtha, A. P., Myatt, L., Mysorekar, I., Williams, S. M., Zhong, N. & Helmer, H., Nov 2017, In : Seminars in Perinatology. 41, 7, p. 438-441 4 p.

Research output: Contribution to journalArticle

1 Scopus citations

Preface IFPA meeting 2016

Myatt, L., Mar 4 2017, (Accepted/In press) In : Placenta.

Research output: Contribution to journalArticle

Sexual dimorphism in the effect of maternal obesity on antioxidant defense mechanisms in the human placenta

Evans, L. S. & Myatt, L., Mar 1 2017, In : Placenta. 51, p. 64-69 6 p.

Research output: Contribution to journalArticle

33 Scopus citations
2016

IFPA meeting 2015 workshop report I: placental mitochondrial function, transport systems and epigenetics

Bianco-Miotto, T., Blundell, C., Buckberry, S., Chamley, L., Chong, S., Cottrell, E., Dawson, P., Hanna, C., Holland, O., Lewis, R. M., Moritz, K., Myatt, L., Perkins, A. V., Powell, T., Saffery, R., Sferruzzi-Perri, A., Sibley, C., Simmons, D. & O'Tierney-Ginn, P. F., Dec 1 2016, In : Placenta. 48, p. S3-S6

Research output: Contribution to journalArticle

2 Scopus citations

Inhibition of lysyl oxidase by cortisol regeneration in human amnion: Implications for rupture of fetal membranes

Liu, C., Guo, C., Wang, W., Zhu, P., Li, W., Mi, Y., Myatt, L. & Sun, K., Jan 1 2016, In : Endocrinology. 157, 10, p. 4055-4065 11 p.

Research output: Contribution to journalArticle

17 Scopus citations

Inhibition of lysyl oxidase by prostaglandin E2 via EP2/EP4 receptors in human amnion fibroblasts: Implications for parturition

Liu, C., Zhu, P., Wang, W., Li, W., Shu, Q., Chen, Z. J., Myatt, L. & Sun, K., Mar 15 2016, In : Molecular and Cellular Endocrinology. 424, p. 118-127 10 p.

Research output: Contribution to journalArticle

7 Scopus citations

Is Mid-trimester Insulin Resistance Predictive of Subsequent Puerperal Infection? A Secondary Analysis of Randomized Trial Data

Hughes, B. L., Clifton, R. G., Hauth, J. C., Leveno, K. J., Myatt, L., Reddy, U. M., Varner, M. W., Wapner, R. J., Mercer, B. M., Peaceman, A. M., Ramin, S. M., Tolosa, J. E., Saade, G. & Sorokin, Y., Aug 1 2016, In : American journal of perinatology. 33, 10, p. 983-990 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Mitochondrial function and glucose metabolism in the placenta with gestational diabetes mellitus: Role of miR-143

Muralimanoharan, S., Maloyan, A. & Myatt, L., 2016, In : Clinical Science. 130, 11, p. 931-941 11 p.

Research output: Contribution to journalArticle

47 Scopus citations

Obesity and Placental Function

Myatt, L. & Maloyan, A., Jan 6 2016, In : Seminars in Reproductive Medicine. 34, 1, p. 42-49 8 p.

Research output: Contribution to journalArticle

43 Scopus citations

Placental origins of adverse pregnancy outcomes: potential molecular targets: an Executive Workshop Summary of the Eunice Kennedy Shriver National Institute of Child Health and Human Development

Ilekis, J. V., Tsilou, E., Fisher, S., Abrahams, V. M., Soares, M. J., Cross, J. C., Zamudio, S., Illsley, N. P., Myatt, L., Colvis, C., Costantine, M. M., Haas, D. M., Sadovsky, Y., Weiner, C., Rytting, E. & Bidwell, G., Jul 1 2016, In : American Journal of Obstetrics and Gynecology. 215, 1, p. S1-S46

Research output: Contribution to journalArticle

98 Scopus citations

Sexual dimorphism in activation of placental autophagy in obese women with evidence for fetal programming from a placenta-specific mouse model

Muralimanoharan, S., Gao, X., Weintraub, S., Myatt, L. & Maloyan, A., May 3 2016, In : Autophagy. 12, 5, p. 752-769 18 p.

Research output: Contribution to journalArticle

25 Scopus citations
2015

Cell-Free Total and Fetal DNA in First Trimester Maternal Serum and Subsequent Development of Preeclampsia

Silver, R. M., Myatt, L., Hauth, J. C., Leveno, K. J., Peaceman, A. M., Ramin, S. M., Samuels, P., Saade, G., Sorokin, Y., Clifton, R. G. & Reddy, U. M., Nov 6 2015, (Accepted/In press) In : American Journal of Perinatology.

Research output: Contribution to journalArticle

7 Scopus citations

Current controversies in prenatal diagnosis 2: Prediction and prevention of adverse pregnancy outcomes requires a genomic rather than proteomic solution

Chiu, R. W. K., Myatt, L. & Otaño, L., Jan 1 2015, In : Prenatal Diagnosis. 35, 1, p. 15-18 4 p.

Research output: Contribution to journalArticle

Phosphorylation of STAT3 mediates the induction of cyclooxygenase-2 by cortisol in the human amnion at parturition

Wang, W., Guo, C., Zhu, P., Lu, J., Li, W., Liu, C., Xie, H., Myatt, L., Chen, Z. J. & Sun, K., Oct 27 2015, In : Science signaling. 8, 400, RA106.

Research output: Contribution to journalArticle

28 Scopus citations

Prenatal Vitamin C and e supplementation in smokers is associated with reduced placental abruption and preterm birth: A secondary analysis

Abramovici, A., Gandley, R. E., Clifton, R. G., Leveno, K. J., Myatt, L., Wapner, R. J., Thorp, J. M., Mercer, B. M., Peaceman, A. M., Samuels, P., Sciscione, A., Harper, M., Saade, G. & Sorokin, Y., Dec 2015, In : BJOG: An International Journal of Obstetrics and Gynaecology. 122, 13, p. 1740-1747 8 p.

Research output: Contribution to journalArticle

13 Scopus citations

Relationship of Early Pregnancy Waist-to-Hip Ratio versus Body Mass Index with Gestational Diabetes Mellitus and Insulin Resistance

Basraon, S. K., Mele, L., Myatt, L., Roberts, J. M., Hauth, J. C., Leveno, K. J., Varner, M. W., Wapner, R. J., Thorp, J. M., Peaceman, A. M., Ramin, S. M., Sciscione, A., Tolosa, J. E. & Sorokin, Y., Sep 9 2015, In : American journal of perinatology. 33, 1, p. 114-122 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Sexual dimorphism in MIR-210 expression and mitochondrial dysfunction in the placenta with maternal obesity

Muralimanoharan, S., Guo, C., Myatt, L. & Maloyan, A., Aug 6 2015, In : International Journal of Obesity. 39, 8, p. 1274-1281 8 p.

Research output: Contribution to journalArticle

46 Scopus citations

Waist-to-Hip Ratio versus Body Mass Index as Predictor of Obesity-Related Pregnancy Outcomes

Mcdonnold, M., Mele, L. M., Myatt, L., Hauth, J. C., Leveno, K. J., Reddy, U. M. & Mercer, B. M., Oct 30 2015, (Accepted/In press) In : American Journal of Perinatology.

Research output: Contribution to journalArticle

3 Scopus citations
2014

Adverse pregnancy outcomes among women with prior spontaneous or induced abortions

Makhlouf, M. A., Clifton, R. G., Roberts, J. M., Myatt, L., Hauth, J. C., Leveno, K. J., Varner, M. W., Thorp, J. M., Mercer, B. M., Peaceman, A. M., Ramin, S. M., Iams, J. D., Sciscione, A., Tolosa, J. E. & Sorokin, Y., Oct 2014, In : American journal of perinatology. 31, 9, p. 765-772 8 p.

Research output: Contribution to journalArticle

29 Scopus citations

Epigenetics of human myometrium: DNA methylation of genes encoding contraction-associated proteins in term and preterm labor

Mitsuya, K., Singh, N., Sooranna, S. R., Johnson, M. R. & Myatt, L., 2014, In : Biology of reproduction. 90, 5, 98.

Research output: Contribution to journalArticle

16 Scopus citations

Haptoglobin phenotype and abnormal uterine artery Doppler in a racially diverse cohort

Weissgerber, T. L., McGee, P. L., Myatt, L., Hauth, J. C., Varner, M. W., Wapner, R. J., Thorp, J. M., Mercer, B. M., Peaceman, A. M., Ramin, S. M., Samuels, P., Sciscione, A. C., Harper, M., Saade, G., Sorokin, Y. & Eunice Kennedy Shriver, N. I. O. C. H. A. H. D. M. F. M. U. N., Nov 1 2014, In : Journal of Maternal-Fetal and Neonatal Medicine. 27, 17, p. 1728-1733 6 p.

Research output: Contribution to journalArticle

Impaired mitochondrial function in human placenta with increased maternal adiposity

Mele, J., Muralimanoharan, S., Maloyan, A. & Myatt, L., Sep 1 2014, In : American Journal of Physiology - Endocrinology and Metabolism. 307, 5, p. E419-E425

Research output: Contribution to journalArticle

65 Scopus citations

Induction of PGF2α synthesis by cortisol through GR dependent induction of CBR1 in human amnion fibroblasts

Guo, C., Wang, W., Liu, C., Myatt, L. & Sun, K., Aug 2014, In : Endocrinology. 155, 8, p. 3017-3024 8 p.

Research output: Contribution to journalArticle

20 Scopus citations

Laboratory abnormalities in pregnancy-associated hypertension: Frequency and association with pregnancy outcomes

Cantu, J., Clifton, R. G., Roberts, J. M., Leveno, K. J., Myatt, L., Reddy, U. M., Varner, M. W., Wapner, R. J., Thorp, J. M., Mercer, B. M., Peaceman, A. M., Ramin, S. M., Samuels, P., Sciscione, A., Saade, G. & Sorokin, Y., Jan 1 2014, In : Obstetrics and gynecology. 124, 5, p. 933-940 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

Optimising sample collection for placental research

Burton, G. J., Sebire, N. J., Myatt, L., Tannetta, D., Wang, Y. L., Sadovsky, Y., Staff, A. C. & Redman, C. W., Jan 2014, In : Placenta. 35, 1, p. 9-22 14 p.

Research output: Contribution to journalArticle

95 Scopus citations

Roles of glucocorticoids in human parturition: A controversial fact?

Li, X. Q., Zhu, P., Myatt, L. & Sun, K., May 2014, In : Placenta. 35, 5, p. 291-296 6 p.

Research output: Contribution to journalArticle

35 Scopus citations

Strategy for standardization of preeclampsia research study design

Myatt, L., Redman, C. W., Staff, A. C., Hansson, S., Wilson, M. L., Laivuori, H., Poston, L. & Roberts, J. M., Jun 2014, In : Hypertension. 63, 6, p. 1293-1301 9 p.

Research output: Contribution to journalArticle

113 Scopus citations
2013

Can changes in angiogenic biomarkers between the first and second trimesters of pregnancy predict development of pre-eclampsia in a low-risk nulliparous patient population?

Myatt, L., Clifton, R. G., Roberts, J. M., Spong, C. Y., Wapner, R. J., Thorp, J. M., Mercer, B. M., Peaceman, A. M., Ramin, S. M., Carpenter, M. W., Sciscione, A., Tolosa, J. E., Saade, G., Sorokin, Y. & Anderson, G. D., Sep 1 2013, In : BJOG: An International Journal of Obstetrics and Gynaecology. 120, 10, p. 1183-1191 9 p.

Research output: Contribution to journalArticle

58 Scopus citations

Evidence of sexual dimorphism in the placental function with severe preeclampsia

Muralimanoharan, S., Maloyan, A. & Myatt, L., Dec 1 2013, In : Placenta. 34, 12, p. 1183-1189 7 p.

Research output: Contribution to journalArticle

40 Scopus citations

Haptoglobin Phenotype, Preeclampsia Risk and the Efficacy of Vitamin C and E Supplementation to Prevent Preeclampsia in a Racially Diverse Population

Weissgerber, T. L., Gandley, R. E., McGee, P. L., Spong, C. Y., Myatt, L., Leveno, K. J., Thorp, J. M., Mercer, B. M., Peaceman, A. M., Ramin, S. M., Carpenter, M. W., Samuels, P., Sciscione, A., Harper, M., Tolosa, J. E., Saade, G. & Sorokin, Y., Apr 3 2013, In : PloS one. 8, 4, e60479.

Research output: Contribution to journalArticle

13 Scopus citations

Human Labour is Associated with a Decline in Myometrial Chemokine Receptor Expression: The Role of Prostaglandins, Oxytocin and Cytokines

Hua, R., Pease, J. E., Cheng, W., Sooranna, S. R., Viney, J. M., Nelson, S. M., Myatt, L., Bennett, P. R. & Johnson, M. R., Jan 1 2013, In : American Journal of Reproductive Immunology. 69, 1, p. 21-32 12 p.

Research output: Contribution to journalArticle

4 Scopus citations

Identification and comparative analyses of myocardial miRNAs involved in the fetal response to maternal obesity

Maloyan, A., Muralimanoharan, S., Huffman, S., Cox, L. A., Nathanielsz, P. W., Myatt, L. & Nijland, M. J., Oct 1 2013, In : Physiological genomics. 45, 19, p. 889-900 12 p.

Research output: Contribution to journalArticle

47 Scopus citations

Pregnancy outcomes with weight gain above or below the 2009 institute of medicine guidelines

Johnson, J., Clifton, R. G., Roberts, J. M., Myatt, L., Hauth, J. C., Spong, C. Y., Varner, M. W., Wapner, R. J., Thorp, J. M., Mercer, B. M., Peaceman, A. M., Ramin, S. M., Samuels, P., Sciscione, A., Harper, M., Tolosa, J. E., Saade, G. & Sorokin, Y., May 1 2013, In : Obstetrics and gynecology. 121, 5, p. 969-975 7 p.

Research output: Contribution to journalArticle

134 Scopus citations

Sexually dimorphic effects of maternal nutrient reduction on expression of genes regulating cortisol metabolism in fetal baboon adipose and liver tissues

Guo, C., Li, C., Myatt, L., Nathanielsz, P. W. & Sun, K., Apr 1 2013, In : Diabetes. 62, 4, p. 1175-1185 11 p.

Research output: Contribution to journalArticle

40 Scopus citations
2012

A standardized template for clinical studies in preterm birth

Myatt, L., Eschenbach, D. A., Lye, S. J., Mesiano, S., Murtha, A. P., Williams, S. M. & Pennell, C. E., May 1 2012, In : Reproductive Sciences. 19, 5, p. 474-482 9 p.

Research output: Contribution to journalArticle

19 Scopus citations