• 6292 Citations
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1982 …2020

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2019

Altered Protein Dynamics and Increased Aggregation of Human γs-Crystallin Due to Cataract-Associated Deamidations

Forsythe, H. M., Vetter, C. J., Jara, K. A., Reardon, P. N., David, L. L., Barbar, E. J. & Lampi, K. J., Oct 8 2019, In : Biochemistry. 58, 40, p. 4112-4124 13 p.

Research output: Contribution to journalArticle

3 Scopus citations

Identification, Quantification, and System Analysis of Protein N-ε Lysine Methylation in Anucleate Blood Platelets

Rocheleau, A. D., Melrose, A. R., Cunliffe, J. M., Klimek, J., Babur, O., Tassi Yunga, S., Ngo, A. T. P., Pang, J., David, L., McCarty, O. & Aslan, J., Jan 1 2019, In : Proteomics. 1900001.

Research output: Contribution to journalArticle

Identification of PKCα-dependent phosphoproteins in mouse retina

Wakeham, C. M., Wilmarth, P., Cunliffe, J. M., Klimek, J. E., Ren, G., David, L. & Morgans, C., Aug 30 2019, In : Journal of Proteomics. 206, 103423.

Research output: Contribution to journalArticle

2 Scopus citations

Mechanism of pharmacochaperoning in a mammalian KATP channel revealed by cryo-EM

Martin, G. M., Sung, M. W., Yang, Z., Innes, L. M., Kandasamy, B., David, L., Yoshioka, C. & Shyng, S-L., Jul 1 2019, In : eLife. 8, e46417.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Proteome-transcriptome analysis and proteome remodeling in mouse lens epithelium and fibers

Zhao, Y., Wilmarth, P. A., Cheng, C., Limi, S., Fowler, V. M., Zheng, D., David, L. L. & Cvekl, A., Feb 2019, In : Experimental Eye Research. 179, p. 32-46 15 p.

Research output: Contribution to journalArticle

10 Scopus citations

Structure of the gene therapy vector, adeno-associated virus with its cell receptor, AAVR

Meyer, N. L., Hu, G., Davulcu, O., Xie, Q., Noble, A. J., Yoshioka, C., Gingerich, D. S., Trzynka, A., David, L., Stagg, S. M. & Chapman, M., May 22 2019, In : eLife. 8

Research output: Contribution to journalArticle

Open Access
5 Scopus citations
2018
1 Scopus citations

Anticancer Pyrroloquinazoline LBL1 Targets Nuclear Lamins

Li, B. X., Chen, J., Chao, B., David, L. & Xiao, X., May 18 2018, In : ACS Chemical Biology. 13, 5, p. 1380-1387 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Biomechanical rigidity and quantitative proteomics analysis of segmental regions of the trabecular meshwork at physiologic and elevated pressures

Vranka, J., Staverosky, J., Reddy, A. P., Wilmarth, P., David, L., Acott, T., Russell, P. & Raghunathan, V. K., Jan 1 2018, In : Investigative Ophthalmology and Visual Science. 59, 1, p. 246-259 14 p.

Research output: Contribution to journalArticle

5 Scopus citations

Combining Chemical Genetics with Proximity-Dependent Labeling Reveals Cellular Targets of Poly(ADP-ribose) Polymerase 14 (PARP14)

Carter-O'Connell, I., Vermehren-Schmaedick, A., Jin, H., Morgan, R. K., David, L. & Cohen, M., Oct 19 2018, In : ACS Chemical Biology. 13, 10, p. 2841-2848 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Coordinated responses to individual tumor antigens by IgG antibody and CD8+ T cells following cancer vaccination

Hulett, T. W., Jensen, S. M., Wilmarth, P., Reddy, A. P., Ballesteros-Merino, C., Afentoulis, M. E., Dubay, C., David, L. & Fox, B. A., Apr 5 2018, In : Journal for ImmunoTherapy of Cancer. 6, 1, 27.

Research output: Contribution to journalArticle

4 Scopus citations

Data Descriptor: Mass spectrometry quantitation of proteins from small pools of developing auditory and vestibular cells

Krey, J. F., Scheffer, D. I., Choi, D., Reddy, A., David, L. L., Corey, D. P. & Barr-Gillespie, P. G., Jul 17 2018, In : Scientific Data. 5, 180128.

Research output: Contribution to journalArticle

1 Scopus citations

ELMOD1 stimulates ARF6-GTP hydrolysis to stabilize apical structures in developing vestibular hair cells

Krey, J. F., Dumont, R. A., Wilmarth, P., David, L., Johnson, K. R. & Barr-Gillespie, P., Jan 24 2018, In : Journal of Neuroscience. 38, 4, p. 843-857 15 p.

Research output: Contribution to journalArticle

4 Scopus citations

MHC class I loaded ligands from breast cancer cell lines: A potential HLA-I-typed antigen collection

Rozanov, D., Rozanov, N. D., Chiotti, K. E., Reddy, A., Wilmarth, P., David, L., Cha, S. W., Woo, S., Pevzner, P., Bafna, V., Burrows, G. G., Rantala, J. K., Levin, T., Anur, P., Johnson-Camacho, K., Tabatabaei, S., Munson, D. J., Bruno, T. C., Slansky, J. E., Kappler, J. W. & 9 others, Hirano, N., Boegel, S., Fox, B. A., Egelston, C., Simons, D. L., Jimenez, G., Lee, P. P., Gray, J. & Spellman, P., Mar 30 2018, In : Journal of Proteomics. 176, p. 13-23 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

Platelet procoagulant phenotype is modulated by a p38-MK2 axis that regulates RTN4/Nogo proximal to the endoplasmic reticulum: utility of pathway analysis

Babur, O., Ngo, A. T. P., Rigg, R. A., Pang, J., Rub, Z. T., Buchanan, A. E., Mitrugno, A., David, L., McCarty, O., Demir, E. & Aslan, J., May 1 2018, In : American journal of physiology. Cell physiology. 314, 5, p. C603-C615

Research output: Contribution to journalArticle

3 Scopus citations
2017

Extended multiplexing of tandem mass tags (TMT) labeling reveals age and high fat diet specific proteome changes in mouse epididymal adipose tissue

Plubell, D. L., Wilmarth, P., Zhao, Y., Fenton, A. M., Minnier, J., Reddy, A. P., Klimek, J., Yang, X., David, L. & Pamir, N., May 1 2017, In : Molecular and Cellular Proteomics. 16, 5, p. 873-890 18 p.

Research output: Contribution to journalArticle

37 Scopus citations
16 Scopus citations
5 Scopus citations

Persulfide Formation Mediates Cysteine and Homocysteine Biosynthesis in Methanosarcina acetivorans

Rauch, B. J., Klimek, J., David, L. & Perona, J. J., Feb 28 2017, In : Biochemistry. 56, 8, p. 1051-1061 11 p.

Research output: Contribution to journalArticle

4 Scopus citations

Proteomic analysis of the bovine and human ciliary zonule

De Maria, A., Wilmarth, P. A., David, L. L. & Bassnett, S., Jan 1 2017, In : Investigative Ophthalmology and Visual Science. 58, 1, p. 573-585 13 p.

Research output: Contribution to journalArticle

19 Scopus citations
7 Scopus citations

The zebrafish as a model system for analyzing mammalian and native α-crystallin promoter function

Posner, M., Murray, K. L., McDonald, M. S., Eighinger, H., Andrew, B., Drossman, A., Haley, Z., Nussbaum, J., David, L. & Lampi, K., Jan 1 2017, In : PeerJ. 2017, 11, 4093.

Research output: Contribution to journalArticle

3 Scopus citations
2016

Cyanide and the human brain: perspectives from a model of food (cassava) poisoning

Tshala-Katumbay, D., Ngombe, N. N., Okitundu, D., David, L., Westaway, S., Boivin, M. J., Mumba, N. D. & Banea, J. P., Aug 1 2016, In : Annals of the New York Academy of Sciences. 1378, 1, p. 50-57 8 p.

Research output: Contribution to journalArticle

7 Scopus citations

Differences in solution dynamics between lens β-crystallin homodimers and heterodimers probed by hydrogen-deuterium exchange and deamidation

Lampi, K. J., Murray, M. R., Peterson, M. P., Eng, B. S., Yue, E., Clark, A. R., Barbar, E. & David, L. L., Jan 2016, In : Biochimica et Biophysica Acta - General Subjects. 1860, 1, p. 304-314 11 p.

Research output: Contribution to journalArticle

1 Scopus citations

Evidence that the Rhodopsin Kinase (GRK1) N-Terminus and the Transducin Gα C-Terminus Interact with the Same "hydrophobic Patch" on Rhodopsin TM5

Jones Brunette, A. M., Sinha, A., David, L. & Farrens, D., Jun 7 2016, In : Biochemistry. 55, 22, p. 3123-3135 13 p.

Research output: Contribution to journalArticle

5 Scopus citations

γ-Crystallins of the chicken lens: Remnants of an ancient vertebrate gene family in birds

Chen, Y., Sagar, V., Len, H. S., Peterson, K., Fan, J., Mishra, S., Mcmurtry, J., Wilmarth, P., David, L. & Wistow, G., 2016, (Accepted/In press) In : FEBS Journal.

Research output: Contribution to journalArticle

7 Scopus citations
2015

A novel, stable, aqueous Glucagon formulation using Ferulic acid as an Excipient

Bakhtiani, P. A., Caputo, N., Castle, J. R., Youssef, J. E., Carroll, J. M., David, L. L., Roberts, C. T. & Kenneth, W., Jan 1 2015, In : Journal of Diabetes Science and Technology. 9, 1, p. 17-23 7 p.

Research output: Contribution to journalArticle

16 Scopus citations

Coordinate regulation of residual bone marrow function by paracrine trafficking of AML exosomes

Huan, J., Hornick, N. I., Goloviznina, N. A., Kamimae-Lanning, A. N., David, L., Wilmarth, P., Mori, M. T., Chevillet, J. R., Narla, A., Roberts, C., Loriaux, M., Chang, B. & Kurre, P., Jun 25 2015, (Accepted/In press) In : Leukemia.

Research output: Contribution to journalArticle

40 Scopus citations

Cotranslational Stabilization of Sec62/63 within the ER Sec61 Translocon Is Controlled by Distinct Substrate-Driven Translocation Events

Conti, B. J., Devaraneni, P. K., Yang, Z., David, L. L. & Skach, W. R., Apr 16 2015, In : Molecular Cell. 58, 2, p. 269-283 15 p.

Research output: Contribution to journalArticle

41 Scopus citations

Data detailing the platelet acetyl-lysine proteome

Aslan, J. E., David, L. L. & McCarty, O. J. T., Dec 1 2015, In : Data in Brief. 5, p. 368-371 4 p.

Research output: Contribution to journalArticle

1 Scopus citations
3 Scopus citations

Hair-bundle proteomes of avian and mammalian inner-ear utricles

Wilmarth, P. A., Krey, J. F., Shin, J. B., Choi, D., David, L. L. & Barr-Gillespie, P. G., Dec 8 2015, In : Scientific Data. 2, 150074.

Research output: Contribution to journalArticle

10 Scopus citations

Identifying Family-Member-Specific Targets of Mono-ARTDs by Using a Chemical Genetics Approach

Carter-O'Connell, I., Jin, H., Morgan, R. K., Zaja, R., David, L., Ahel, I. & Cohen, M., Jul 22 2015, (Accepted/In press) In : Cell Reports.

Research output: Contribution to journalArticle

33 Scopus citations

Lysine acetyltransfer supports platelet function

Aslan, J. E., Rigg, R. A., Nowak, M. S., Loren, C. P., Baker-Groberg, S. M., Pang, J., David, L. L. & Mccarty, O. J. T., Oct 1 2015, In : Journal of Thrombosis and Haemostasis. 13, 10, p. 1908-1917 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

Role for Rab10 in methamphetamine-induced behavior

Vanderwerf, S. M., Buck, D. C., Wilmarth, P. A., Sears, L. M., David, L. L., Morton, D. B. & Neve, K. A., Aug 20 2015, In : PloS one. 10, 8, e0136167.

Research output: Contribution to journalArticle

6 Scopus citations

Separating myoblast differentiation from muscle cell fusion using IGF-I and the p38 MAP kinase inhibitor SB202190

Gardner, S., Gross, S. M., David, L. L., Klimek, J. E. & Rotwein, P., Sep 1 2015, In : American Journal of Physiology - Cell Physiology. 309, 7, p. C491-C500

Research output: Contribution to journalArticle

11 Scopus citations

Solution-phase crosstalk and regulatory interactions between multipotent adult progenitor cells and peripheral blood mononuclear cells

Burrows, G. G., Hof, W. VT., Reddy, A. P., Wilmarth, P., David, L., Raber, A., Bogaerts, A., Timmerman, L., Pinxteren, J., Roobrouck, V. D., Deans, R. J. & Maziarz, R., Dec 1 2015, In : Stem cells translational medicine. 4, 12, p. 1436-1449 14 p.

Research output: Contribution to journalArticle

2 Scopus citations
2014

Accurate label-free protein quantitation with high- and low-resolution mass spectrometers

Krey, J. F., Wilmarth, P. A., Shin, J. B., Klimek, J., Sherman, N. E., Jeffery, E. D., Choi, D., David, L. L. & Barr-Gillespie, P. G., Feb 7 2014, In : Journal of Proteome Research. 13, 2, p. 1034-1044 11 p.

Research output: Contribution to journalArticle

56 Scopus citations

Biochemical stabilization of glucagon at alkaline pH

Caputo, N., Jackson, M. A., Castle, J. R., El Youssef, J., Bakhtiani, P. A., Bergstrom, C. P., Carroll, J. M., Breen, M. E., Leonard, G. L., David, L. L., Roberts, C. T. & Ward, W. K., Jan 1 2014, In : Diabetes Technology and Therapeutics. 16, 11, p. 747-758 12 p.

Research output: Contribution to journalArticle

11 Scopus citations

Correlation of actin crosslinker and capper expression levels with stereocilia growth phases

Avenarius, M. R., Saylor, K. W., Lundeberg, M. R., Wilmarth, P. A., Shin, J. B., Spinelli, K. J., Pagana, J. M., Andrade, L., Kachar, B., Choi, D., David, L. L. & Barr-Gillespie, P. G., Feb 1 2014, In : Molecular and Cellular Proteomics. 13, 2, p. 606-620 15 p.

Research output: Contribution to journalArticle

18 Scopus citations

Engineering the substrate specificity of ADP-ribosyltransferases for identifying direct protein targets

Carter-O'Connell, I., Jin, H., Morgan, R. K., David, L. L. & Cohen, M. S., Apr 9 2014, In : Journal of the American Chemical Society. 136, 14, p. 5201-5204 4 p.

Research output: Contribution to journalArticle

56 Scopus citations

Glutaredoxin 2 (Grx2) gene deletion induces early onset of age-dependent cataracts in mice

Wu, H., Yu, Y., David, L., Ho, Y. S. & Lou, M. F., Dec 26 2014, In : Journal of Biological Chemistry. 289, 52, p. 36125-36139 15 p.

Research output: Contribution to journalArticle

24 Scopus citations
53 Scopus citations

Metabolic Reprogramming during Purine Stress in the Protozoan Pathogen Leishmania donovani

Martin, J. L., Yates, P. A., Soysa, R., Alfaro, J. F., Yang, F., Burnum-Johnson, K. E., Petyuk, V. A., Weitz, K. K., Camp, D. G., Smith, R. D., Wilmarth, P. A., David, L. L., Ramasamy, G., Myler, P. J. & Carter, N. S., Feb 2014, In : PLoS pathogens. 10, 2, e1003938.

Research output: Contribution to journalArticle

36 Scopus citations
26 Scopus citations

Nascent proteomes in peripheral blood mononuclear cells as a novel source for biomarker discovery in human stroke

Bian, F., Simon, R. P., Li, Y., David, L., Wainwright, J., Hall, C. L., Frankel, M. & Zhou, A., Apr 2014, In : Stroke. 45, 4, p. 1177-1179 3 p.

Research output: Contribution to journalArticle

9 Scopus citations

Newborn mouse lens proteome and its alteration by lysine 6 mutant ubiquitin

Shang, F., Wilmarth, P. A., Chang, M. L., Liu, K., David, L. L., Caceres, M. A., Wawrousek, E. & Taylor, A., Mar 7 2014, In : Journal of Proteome Research. 13, 3, p. 1177-1189 13 p.

Research output: Contribution to journalArticle

4 Scopus citations
2013

Carbamoylation correlates of cyanate neuropathy and cyanide poisoning: Relevance to the biomarkers of cassava cyanogenesis and motor system toxicity

Kimani, S., Moterroso, V., Lasarev, M., Kipruto, S., Bukachi, F., Maitai, C., David, L. & Tshala-Katumbay, D., Jan 1 2013, In : SpringerPlus. 2, 1, p. 1-8 8 p., 647.

Research output: Contribution to journalArticle

10 Scopus citations

Detection of autoantibodies against heat shock proteins and collapsin response mediator proteins in autoimmune retinopathy

Adamus, G., Bonnah, R., Brown, L. & David, L., Sep 27 2013, In : BMC ophthalmology. 13, 1, 48.

Research output: Contribution to journalArticle

13 Scopus citations