Kyle Ellrott

Assistant Professor

  • 10895 Citations
  • 15 h-Index
20022017

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Proteins Medicine & Life Sciences
proteins Physics & Astronomy
Neoplasms Medicine & Life Sciences
Genome Medicine & Life Sciences
Genes Medicine & Life Sciences
Crystal structure Chemical Compounds
Mutation Medicine & Life Sciences
crystal structure Physics & Astronomy

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Research Output 2002 2017

  • 10895 Citations
  • 15 h-Index
  • 35 Article
  • 1 Conference contribution

A Community Challenge for Inferring Genetic Predictors of Gene Essentialities through Analysis of a Functional Screen of Cancer Cell Lines

Gönen, M. , Weir, B. A. , Cowley, G. S. , Vazquez, F. , Guan, Y. , Jaiswal, A. , Karasuyama, M. , Uzunangelov, V. , Wang, T. , Tsherniak, A. , Howell, S. , Marbach, D. , Hoff, B. , Norman, T. C. , Airola, A. , Bivol, A. , Bunte, K. , Carlin, D. , Chopra, S. , Deran, A. & 25 others Ellrott, K., Gopalacharyulu, P., Graim, K., Kaski, S., Khan, S. A., Newton, Y., Ng, S., Pahikkala, T., Paull, E., Sokolov, A., Tang, H., Tang, J., Wennerberg, K., Xie, Y., Zhan, X., Zhu, F., Aittokallio, T., Mamitsuka, H., Stuart, J. M., Boehm, J. S., Root, D. E., Xiao, G., Stolovitzky, G., Hahn, W. C. & Margolin, A. A. 2017 (Accepted/In press) In : Cell Systems.

Research output: Research - peer-reviewArticle

Cell Line
Genes
Neoplasms
Benchmarking
Datasets
56 Citations

Combining tumor genome simulation with crowdsourcing to benchmark somatic single-nucleotide-variant detection

Ewing, A. D., Houlahan, K. E., Hu, Y., Ellrott, K., Caloian, C., Yamaguchi, T. N., Bare, J. C., P'Ng, C., Waggott, D., Sabelnykova, V. Y., Kellen, M. R., Norman, T. C., Haussler, D., Friend, S. H., Stolovitzky, G., Margolin, A. A., Stuart, J. M. & Boutros, P. C. Jun 30 2015 In : Nature Methods. 12, 7, p. 623-630 8 p.

Research output: Research - peer-reviewArticle

Crowdsourcing
Benchmarking
Nucleotides
Genome
Neoplasms
21 Citations

Global optimization of somatic variant identification in cancer genomes with a global community challenge

Boutros, P. C., Ewing, A. D., Ellrott, K., Norman, T. C., Dang, K. K., Hu, Y., Kellen, M. R., Suver, C., Bare, J. C., Stein, L. D., Spellman, P. T., Stolovitzky, G., Friend, S. H., Margolin, A. A. & Stuart, J. M. 2014 In : Nature Genetics. 46, 4, p. 318-319 2 p.

Research output: Research - peer-reviewArticle

909 Citations

Comprehensivemolecular characterization of clear cell renal cell carcinoma

Creighton, C. J. , Morgan, M. , Gunaratne, P. H. , Wheeler, D. A. , Gibbs, R. A. , Robertson, G. , Chu, A. , Beroukhim, R. , Cibulskis, K. , Signoretti, S. , Vandin, F. , Wu, H. T. , Raphael, B. J. , Verhaak, R. G. W. , Tamboli, P. , Torres-Garcia, W. , Akbani, R. , Weinstein, J. N. , Reuter, V. , Hsieh, J. J. & 268 others Brannon, A. R., Hakimi, A. A., Jacobsen, A., Ciriello, G., Reva, B., Ricketts, C. J., Linehan, W. M., Stuart, J. M., Rathmell, W. K., Hui, S., Laird, P. W., Muzny, D., Davis, C., Liu, X., Chang, K., Kakkar, N., Treviño, L. R., Benton, S., Reid, J. G., Morton, D., Doddapaneni, H., Yi, H., Lewis, L., Huyen, D., Kovar, C., Zhu, Y., Santibanez, J., Min, W., Hale, W., Kalra, D., Getz, G., Lawrence, M. S., Sougnez, C., Carter, S. L., Sivachenko, A., Lee, L., Stewart, C., Voet, D., Fisher, S., Gabriel, S. B., Lander, E., Schumacher, S. E., Tabak, B., Saksena, G., Onofrio, R. C., Cherniack, A. D., Gentry, J., Ardlie, K., Meyerson, M., Chun, H. J. E., Mungall, A. J., Sipahimalani, P., Stoll, D., Ally, A., Balasundaram, M., Butterfield, Y. S. N., Carlsen, R., Carter, C., Chuah, E., Coope, R. J. N., Dhalla, N., Gorski, S., Guin, R., Hirst, C., Hirst, M., Holt, R. A., Lebovitz, C., Lee, D., Li, H. I., Mayo, M., Moore, R. A., Pleasance, E., Plettner, P., Schein, J. E., Shafiei, A., Slobodan, J. R., Tam, A., Thiessen, N., Varhol, R. J., Wye, N., Zhao, Y., Birol, I., Jones, S. J. M., Marra, M. A., Auman, J. T., Tan, D., Jones, C. D., Hoadley, K. A., Mieczkowski, P. A., Mose, L. E., Jefferys, S. R., Topal, M. D., Liquori, C., Turman, Y. J., Yan, S., Waring, S., Buda, E., Walsh, J., Wu, J., Bodenheimer, T., Hoyle, A. P., Simons, J. V., Soloway, M. G., Balu, S., Parker, J. S., Hayes, D. N., Perou, C. M., Kucherlapati, R., Park, P., Triche, T., Weisenberger, D. J., Lai, P. H., Bootwalla, M. S., Maglinte, D. T., Mahurkar, S., Berman, B. P., Van Den Berg, D. J., Cope, L., Baylin, S. B., Noble, M. S., DiCara, D., Zhang, H., Cho, J., Heiman, D. I., Gehlenborg, N., Mallard, W., Pei, L., Frazer, S., Stojanov, P., Liu, Y., Zhou, L., Kim, J., Chin, L., Benz, C., Yau, C., Reynolds, S. M., Shmulevich, I., Vegesna, R., Kim, H., Wei, Z., Cogdell, D., Jonasch, E., Ding, Z., Lu, Y., Zhang, N., Unruh, A. K., Casasent, T. D., Wakefield, C., Tsavachidou, D., Mills, G. B., Gao, J., Cerami, E., Gross, B., Aksoy, B. A., Sinha, R., Weinhold, N., Sumer, S. O., Taylor, B. S., Shen, R., Ostrovnaya, I., Berger, M. F., Ladanyi, M., Sander, C., Fei, S. S., Stout, A., Spellman, P. T., Rubin, D. L., Liu, T. T., Sam, N., Paull, E. O., Carlin, D., Goldstein, T., Waltman, P., Ellrott, K., Jing, Z., Haussler, D., Xiao, W., Shelton, C., Gardner, J., Penny, R., Sherman, M., Mallery, D., Morris, S., Paulauskis, J., Burnett, K., Shelton, T., Kaelin, W. G., Choueiri, T., Atkins, M. B., Curley, E., Tickoo, S., Thorne, L., Boice, L., Mei, H., Fisher, J. C., Vocke, C. D., Peterson, J., Worrell, R., Merino, M. J., Schmidt, L. S., Czerniak, B. A., Aldape, K. D., Wood, C. G., Boyd, J., Weaver, J. E., Iacocca, M. V., Petrelli, N., Witkin, G., Brown, J., Czerwinski, C., Huelsenbeck-Dill, L., Rabeno, B., Myers, J., Morrison, C., Bergsten, J., Eckman, J., Harr, J., Smith, C., Tucker, K., Zach, L. A., Bshara, W., Gaudioso, C., Dhir, R., Maranchie, J., Nelson, J., Parwani, A., Potapova, C. O., Fedosenko, K., Cheville, J. C., Thompson, R. H., Mosquera, J. M., Rubin, M. A., Blute, M. L., Pihl, T., Jensen, M., Sfeir, R., Kahn, A., Chu, A., Kothiyal, P., Snyder, E., Pontius, J., Ayala, B., Backus, M., Walton, J., Baboud, J., Berton, D., Nicholls, M., Srinivasan, D., Raman, R., Girshik, S., Kigonya, P., Alonso, S., Sanbhadti, R., Barletta, S., Pot, D., Sheth, M., Demchok, J. A., Davidsen, T., Wang, Z., Yang, L., Tarnuzzer, R. W., Zhang, J., Eley, G., Ferguson, M. L., Mills Shaw, K. R., Guyer, M. S., Ozenberger, B. A. & Sofia, H. J. 2013 In : Nature. 499, 7456, p. 43-49 7 p.

Research output: Research - peer-reviewArticle

Renal Cell Carcinoma
Genes
Neoplasms
Mutation
PTEN Phosphohydrolase
43 Citations

Enabling transparent and collaborative computational analysis of 12 tumor types within the Cancer Genome Atlas

Omberg, L., Ellrott, K., Yuan, Y., Kandoth, C., Wong, C., Kellen, M. R., Friend, S. H., Stuart, J., Liang, H. & Margolin, A. A. Oct 2013 In : Nature Genetics. 45, 10, p. 1121-1126 6 p.

Research output: Research - peer-reviewArticle

Atlases
Genome
Neoplasms
Synapses
Software