• 9920 Citations
  • 55 h-Index
1978 …2019
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Fingerprint Dive into the research topics where Klaus Frueh is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 10 Similar Profiles
Cytomegalovirus Medicine & Life Sciences
Major Histocompatibility Complex Medicine & Life Sciences
Antigen Presentation Medicine & Life Sciences
Human Herpesvirus 8 Medicine & Life Sciences
T-Lymphocytes Medicine & Life Sciences
Peptides Medicine & Life Sciences
Ubiquitin Medicine & Life Sciences
Proteins Medicine & Life Sciences

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Projects 1978 2019

Mechanisms of orthopoxvirus host control and viral immune evasion

Frueh, K., Fremont, D. H. & Yokoyama, W. M.

National Institutes of Health

3/1/142/28/19

Project: Research project

Cowpox virus
T-Lymphocytes
Orthopoxvirus
Immune Evasion
Smallpox
Plasmodium knowlesi
Subunit Vaccines
Sporozoites
Malaria
Vaccines
Interferon Regulatory Factor-3
Cytomegalovirus
Innate Immunity
Interferons
DNA
Antigen Presentation
Cytomegalovirus
T-Lymphocytes
Vaccines
Adaptive Immunity

Research Output 1987 2019

  • 9920 Citations
  • 55 h-Index
  • 136 Article
  • 2 Comment/debate
  • 2 Review article
  • 1 Conference contribution
5 Citations (Scopus)

Casting a wider net: Immunosurveillance by nonclassical MHC molecules

D'Souza, M. P., Adams, E., Altman, J. D., Birnbaum, M. E., Boggiano, C., Casorati, G., Chien, Y. H., Conley, A., Eckle, S. B. G., Frueh, K., Gondré-Lewis, T., Hassan, N., Huang, H., Jayashankar, L., Kasmar, A. G., Kunwar, N., Lavelle, J., Lewinsohn, D., Moody, B., Picker, L. & 5 others, Ramachandra, L., Shastri, N., Parham, P., McMichael, A. J. & Yewdell, J. W., Feb 1 2019, In : PLoS pathogens. 15, 2, p. e1007567

Research output: Contribution to journalReview article

Open Access
Immunologic Monitoring
Major Histocompatibility Complex
T-Lymphocytes
National Institute of Allergy and Infectious Diseases (U.S.)
HLA-G Antigens
5 Citations (Scopus)

Cytomegalovirus vectors expressing Plasmodium knowlesi antigens induce immune responses that delay parasitemia upon sporozoite challenge

Hansen, S., Womack, J., Scholz, I., Renner, A., Edgel, K. A., Xu, G., Ford, J. C., Grey, M., St. Laurent, B., Turner, J. M., Planer, S., Legasse, A. W., Richie, T. L., Aguiar, J. C., Axthelm, M., Villasante, E. D., Weiss, W., Edlefsen, P. T., Picker, L. & Frueh, K., Jan 1 2019, In : PLoS One. 14, 1, e0210252.

Research output: Contribution to journalArticle

Plasmodium knowlesi
Cytomegalovirus
Sporozoites
T-cells
Parasitemia
8 Citations (Scopus)

Demarcated thresholds of tumor-specific CD8 T cells elicited by MCMV-based vaccine vectors provide robust correlates of protection

Beyranvand Nejad, E., Ratts, R. B., Panagioti, E., Meyer, C., Oduro, J. D., Cicin-Sain, L., Frueh, K., Van Der Burg, S. H. & Arens, R., Jan 31 2019, In : Journal for ImmunoTherapy of Cancer. 7, 1, 25.

Research output: Contribution to journalArticle

Vaccines
Cytomegalovirus Vaccines
T-Lymphocytes
Neoplasms
Cancer Vaccines
3 Citations (Scopus)

Enhancing safety of cytomegalovirus-based vaccine vectors by engaging host intrinsic immunity

Marshall, E., Malouli, D., Hansen, S., Gilbride, R. M., Hughes, C. M., Ventura, A. B., Ainslie, E., Selseth, A. N., Ford, J. C., Burke, D., Kreklywich, C. N., Womack, J., Legasse, A. W., Axthelm, M., Kahl, C., Streblow, D., Edlefsen, P. T., Picker, L. & Frueh, K., Jul 17 2019, In : Science Translational Medicine. 11, 501, eaaw2603.

Research output: Contribution to journalArticle

Cytomegalovirus Vaccines
Cytomegalovirus
Immunity
Safety
Leukocyte Transfusion
1 Citation (Scopus)

Human Cytomegalovirus Immediate Early 86-kDa Protein Blocks Transcription and Induces Degradation of the Immature Interleukin-1β Protein during Virion-Mediated Activation of the AIM2 Inflammasome

Botto, S., Abraham, J., Mizuno, N., Pryke, K., Gall, B., Landais, I., Streblow, D., Frueh, K. & De Filippis, V., Feb 12 2019, In : mBio. 10, 1

Research output: Contribution to journalArticle

Open Access
Inflammasomes
Cytomegalovirus
Interleukin-1
Virion
Melanoma