Kevin Yee

Assistant Professor

  • 1204 Citations
  • 8 h-Index
20022009
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  • 3 Similar Profiles
Phosphotransferases Medicine & Life Sciences
Acute Myeloid Leukemia Medicine & Life Sciences
fms-Like Tyrosine Kinase 3 Medicine & Life Sciences
Protein-Tyrosine Kinases Medicine & Life Sciences
Daunorubicin Medicine & Life Sciences
Cytarabine Medicine & Life Sciences
Receptor Protein-Tyrosine Kinases Medicine & Life Sciences
Mutation Medicine & Life Sciences

Research Output 2002 2009

  • 1204 Citations
  • 8 h-Index
  • 8 Article

The FLT3 inhibitor tandutinib (formerly MLN518) has sequence-independent synergistic effects with cytarabine and daunorubicin

Schittenhelm, M. M., Kampa, K. M., Yee, K. & Heinrich, M., Aug 15 2009, In : Cell Cycle. 8, 16, p. 2621-2630 10 p.

Research output: Contribution to journalArticle

Daunorubicin
Cytarabine
Induction Chemotherapy
Drug Therapy
Mucositis
29 Citations (Scopus)

FLT3 K663Q is a novel AML-associated oncogenic kinase: Determination of biochemical properties and sensitivity to Sunitinib (SU11248)

Schittenhelm, M. M., Yee, K., Tyner, J., McGreevey, L., Haley, A. D., Town, A., Griffith, D. J., Bainbridge, T., Braziel, R., O'Farrell, A. M., Cherrington, J. M. & Heinrich, M., Nov 2006, In : Leukemia. 20, 11, p. 2008-2014 7 p.

Research output: Contribution to journalArticle

Acute Myeloid Leukemia
Phosphotransferases
Mutation
Codon
sunitinib
65 Citations (Scopus)

Sensitivity of oncogenic KIT mutants to the kinase inhibitors MLN518 and PD180970

Corbin, A. S., Griswold, I. J., La Rosée, P., Yee, K., Heinrich, M., Reimer, C. L., Druker, B. & Deininger, M. W. N., Dec 1 2004, In : Blood. 104, 12, p. 3754-3757 4 p.

Research output: Contribution to journalArticle

Systemic Mastocytosis
Acute Myeloid Leukemia
Gastrointestinal Stromal Tumors
Phosphotransferases
Tumors
105 Citations (Scopus)

Synergistic effect of SU11248 with cytarabine or daunorubicin on FLT3 ITD-positive leukemic cells

Yee, K., Schittenhelm, M., O'Farrell, A. M., Town, A. R., McGreevey, L., Bainbridge, T., Cherrington, J. M. & Heinrich, M., Dec 15 2004, In : Blood. 104, 13, p. 4202-4209 8 p.

Research output: Contribution to journalArticle

fms-Like Tyrosine Kinase 3
Daunorubicin
Cytarabine
Acute Myeloid Leukemia
Liver
725 Citations (Scopus)

SU11248 is a novel FLT3 tyrosine kinase inhibitor with potent activity in vitro and in vivo

O'Farrell, A. M., Abrams, T. J., Yuen, H. A., Ngai, T. J., Louie, S. G., Yee, K., Wong, L. M., Hong, W., Lee, L. B., Town, A., Smolich, B. D., Manning, W. C., Murray, L. J., Heinrich, M. & Cherrington, J. M., May 1 2003, In : Blood. 101, 9, p. 3597-3605 9 p.

Research output: Contribution to journalArticle

Protein-Tyrosine Kinases
Tumors
Acute Myeloid Leukemia
Phosphorylation
Heterografts