Julia Maxson

Assistant Professor

Assistant Professor, Knight Cancer Institute

Emailmaxsonj@ohsu.edu

903 Citations
14 h-Index

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8 Similar Profiles

Leukemia, Neutrophilic, Chronic Medicine & Life Sciences

Mutation Medicine & Life Sciences

Colony-Stimulating Factor Receptors Medicine & Life Sciences

Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative Medicine & Life Sciences

Leukemia Medicine & Life Sciences

Hepcidins Medicine & Life Sciences

Granulocyte Colony-Stimulating Factor Receptors Chemical Compounds

Chemical activation Chemical Compounds

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Projects

Pathogenic Mechanisms of CSF3R Mutations in Leukemia

Maxson, J.

Project: Research project

Research Output 2007 2019

903 Citations
14 h-Index
23 Article
2 Letter
2 Review article

Genomic landscape of neutrophilic leukemias of ambiguous diagnosis

Zhang, H., Wilmot, B., Bottomly, D., Dao, K. H. T., Stevens, E., Eide, C. A., Khanna, V., Rofelty, A., Savage, S., Schultz, A. R., Long, N., White, L., Carlos, A., Henson, R., Lin, C., Searles, R., Collins, R. H., DeAngelo, D. J., Deininger, M. W., Dunn, T. & 12 others, Hein, T., Luskin, M. R., Medeiros, B. C., Oh, S. T., Pollyea, D. A., Steensma, D. P., Stone, R. M., Druker, B. J., McWeeney, S. K., Maxson, J. E., Gotlib, J. R. & Tyner, J. W., Sep 12 2019, In : Blood. 134, 11, p. 867-879 13 p.

Research output: Contribution to journal › Article

Leukemia

Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative

Leukemia, Neutrophilic, Chronic

Exome

RNA Sequence Analysis

Myeloid lineage enhancers drive oncogene synergy in CEBPA/CSF3R mutant acute myeloid leukemia

Braun, T. P., Okhovat, M., Coblentz, C., Carratt, S. A., Foley, A., Schonrock, Z., Smith, B. M., Nevonen, K., Davis, B., Garcia, B., LaTocha, D., Weeder, B. R., Grzadkowski, M. R., Estabrook, J. C., Manning, H. G., Watanabe-Smith, K., Jeng, S., Smith, J. L., Leonti, A. R., Ries, R. E. & 8 others, McWeeney, S., Di Genua, C., Drissen, R., Nerlov, C., Meshinchi, S., Carbone, L., Druker, B. J. & Maxson, J. E., Dec 1 2019, In : Nature communications. 10, 1, 5455.

Research output: Contribution to journal › Article

Open Access

Granulocyte Colony-Stimulating Factor Receptors

oncogenes

leukemias

mutations

Oncogenes

1 Citation (Scopus)

A novel germline variant in CSF3R reduces N-glycosylation and exerts potent oncogenic effects in leukemia

Spiciarich, D. R., Oh, S. T., Foley, A., Hughes, S. B., Mauro, M. J., Abdel-Wahab, O., Press, R., Viner, R., Thompson, S. L., Chen, Q., Azadi, P., Bertozzi, C. R. & Maxson, J., Dec 15 2018, In : Cancer Research. 78, 24, p. 6762-6770 9 p.

Research output: Contribution to journal › Article

Colony-Stimulating Factor Receptors

Glycosylation

Leukemia

Ligands

Mutation

4 Citations (Scopus)

Gain-of-function mutations in granulocyte colony–stimulating factor receptor (CSF3R) reveal distinct mechanisms of CSF3R activation

Zhang, H., Coblentz, C., Watanabe-Smith, K., Means, S., Means, J., Maxson, J. & Tyner, J., Jan 1 2018, In : Journal of Biological Chemistry. 293, 19, p. 7387-7396 10 p.

Research output: Contribution to journal › Article

Granulocytes

Chemical activation

Mutation

Substitution reactions

Dimerization

Synthetic lethality of TNK2 inhibition in PTPN11-mutant leukemia

Jenkins, C., Luty, S. B., Maxson, J., Eide, C. A., Abel, M. L., Togiai, C., Nemecek, E., Bottomly, D., McWeeney, S., Wilmot, B., Loriaux, M., Chang, B. & Tyner, J., Jul 17 2018, In : Science Signaling. 11, 539, eaao5617.

Research output: Contribution to journal › Article

Juvenile Myelomonocytic Leukemia

Leukemia

Acute Myeloid Leukemia

Myeloid Cells

Mitogen-Activated Protein Kinases