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Jonah Sacha

Assistant Professor

  • 2293 Citations
  • 22 h-Index
20042019
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  • 27 Similar Profiles
Simian Immunodeficiency Virus Medicine & Life Sciences
T-Lymphocytes Medicine & Life Sciences
Simian immunodeficiency virus Agriculture & Biology
T-lymphocytes Agriculture & Biology
Macaca Medicine & Life Sciences
HIV Medicine & Life Sciences
Macaca mulatta Medicine & Life Sciences
Epitopes Medicine & Life Sciences

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Projects 2010 2019

A nonhuman primate model of stem cell transplantation to understand determinants of post-transplant SIV clearance

Sacha, J.

Project: Research project

An IL-15 superagonist approach to clear the latent viral reservoir

Sacha, J.

Project: Research project

Understanding Unconventional CD8+ T cell Responses in Protection from HIV

Hansen, S. & Sacha, J.

Project: Research project

Impact of retroviral infection on non-classical, mycobacteria-specific T cells.

Hansen, S. & Sacha, J.

National Institutes of Health

7/1/16 → 6/30/18

Project: Research project

Mycobacterium
Tuberculosis
T-Lymphocytes
Infection
HIV

A universal MHC-E-restricted T cell vaccine for HIV

Sacha, J.

National Institutes of Health

3/1/15 → 2/28/19

Project: Research project

AIDS Vaccines
nef Gene Products
T-Lymphocytes
HLA-A Antigens
HLA-B Antigens

Research Output 2004 2019

  • 2293 Citations
  • 22 h-Index
  • 55 Article
  • 2 Comment/debate

Vaccine-Mediated Inhibition of the Transporter Associated with Antigen Processing Is Insufficient To Induce Major Histocompatibility Complex E-Restricted CD8+ T Cells in Nonhuman Primates

Abdulhaqq, S. A., Wu, H., Schell, J. B., Hammond, K. B., Reed, J. S., Legasse, A. W., Axthelm, M., Park, B., Asokan, A., Frueh, K., Hansen, S., Picker, L. & Sacha, J., Oct 1 2019, In : Journal of virology. 93, 19

Research output: Contribution to journal › Article

Antigen Presentation
major histocompatibility complex
Major Histocompatibility Complex
Primates
transporters
8 Citations (Scopus)

Combination adenovirus and protein vaccines prevent infection or reduce viral burden after heterologous clade C simian-human immunodeficiency virus mucosal challenge

Malherbe, D., Mendy, J., Vang, L., Barnette, P. T., Reed, J., Lakhashe, S. K., Owuor, J., Gach, J. S., Legasse, A. W., Axthelm, M., LaBranche, C. C., Montefiori, D., Forthal, D. N., Park, B., Wilson, J. M., McLinden, J. H., Xiang, J., Stapleton, J. T., Sacha, J., Haynes, B. F. & 6 others, Liao, H. X., Ruprecht, R. M., Smith, J., Gurwith, M., Haigwood, N. & Alexander, J., Jan 1 2018, In : Journal of Virology. 92, 2, e01092-17.

Research output: Contribution to journal › Article

Adenovirus Vaccines
Combined Vaccines
Simian Immunodeficiency Virus
Human immunodeficiency virus
Macaca

Erratum: Author Correction: Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding (Nature communications (2018) 9 1 (3137))

Walters, L. C., Harlos, K., Brackenridge, S., Rozbesky, D., Barrett, J. R., Jain, V., Walter, T. S., O'Callaghan, C. A., Borrow, P., Toebes, M., Hansen, S., Sacha, J., Abdulhaqq, S., Greene, J. M., Frueh, K., Marshall, E., Picker, L., Jones, E. Y., McMichael, A. J. & Gillespie, G. M., Nov 13 2018, In : Nature Communications. 9, 1, 1 p.

Research output: Contribution to journal › Comment/debate

pathogens
Pathogens
Anchors
peptides
Epitopes
7 Citations (Scopus)

Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding

Walters, L. C., Harlos, K., Brackenridge, S., Rozbesky, D., Barrett, J. R., Jain, V., Walter, T. S., O’Callaghan, C. A., Borrow, P., Toebes, M., Hansen, S., Sacha, J., Abdulhaqq, S., Greene, J. M., Frueh, K., Marshall, E., Picker, L., Jones, E. Y., McMichael, A. J. & Gillespie, G. M., Dec 1 2018, In : Nature Communications. 9, 1, 3137.

Research output: Contribution to journal › Article

leukocytes
pathogens
antigens
Pathogens
HLA Antigens
15 Citations (Scopus)

The human IL-15 superagonist ALT-803 directs SIV-specific CD8+ T cells into B-cell follicles

Webb, G. M., Li, S., Mwakalundwa, G., Folkvord, J. M., Greene, J. M., Reed, J. S., Stanton, J., Legasse, A. W., Hobbs, T., Martin, L. D., Park, B., Whitney, J. B., Jeng, E. K., Wong, H. C., Nixon, D. F., Jones, R. B., Connick, E., Skinner, P. J. & Sacha, J., Jan 23 2018, In : Blood advances. 2, 2, p. 76-84 9 p.

Research output: Contribution to journal › Article

Simian Immunodeficiency Virus
B-Lymphocytes
T-Lymphocytes
HIV
Macaca