Jonah Sacha

Assistant Professor

Assistant Professor, Vaccine and Gene Therapy Institute

Emailsacha@ohsu.edu

Source: Scopus
Calculated based on no. of publications stored in Pure and citations from Scopus

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7 Finished

A nonhuman primate model of stem cell transplantation to understand determinants of post-transplant SIV clearance
Sacha, J.
Project: Research project
Effect of obesity on HIV pathogenesis, antiretroviral therapy, and metabolic comorbidities
Sacha, J., Kievit, P. & Roberts, C.
Project: Research project
An IL-15 superagonist approach to clear the latent viral reservoir
Sacha, J.
Project: Research project
A CCR5 Blocking Antibody as HIV Pre-exposure Prophylaxis
Sacha, J.
Project: Research project
Understanding Unconventional CD8+ T cell Responses in Protection from HIV
Hansen, S. & Sacha, J.
Project: Research project

2932 Citations
25 h-Index
63 Article
4 Comment/debate
3 Review article

CCR5 inhibition in critical COVID-19 patients decreases inflammatory cytokines, increases CD8 T-cells, and decreases SARS-CoV2 RNA in plasma by day 14
Patterson, B. K., Seethamraju, H., Dhody, K., Corley, M. J., Kazempour, K., Lalezari, J., Pang, A. P. S., Sugai, C., Mahyari, E., Francisco, E. B., Pise, A., Rodrigues, H., Wu, H. L., Webb, G. M., Park, B. S., Kelly, S., Pourhassan, N., Lelic, A., Kdouh, L., Herrera, M. & 10 others, Hall, E., Bimber, B. N., Plassmeyer, M., Gupta, R., Alpan, O., O'Halloran, J. A., Mudd, P. A., Akalin, E., Ndhlovu, L. C. & Sacha, J. B., Feb 2021, In: International Journal of Infectious Diseases. 103, p. 25-32 8 p.
Research output: Contribution to journal › Article › peer-review

Open Access
7 Scopus citations
Disruption of CCR5 signaling to treat COVID-19-associated cytokine storm: Case series of four critically ill patients treated with leronlimab
Agresti, N., Lalezari, J. P., Amodeo, P. P., Mody, K., Mosher, S. F., Seethamraju, H., Kelly, S. A., Pourhassan, N. Z., Sudduth, C. D., Bovinet, C., ElSharkawi, A. E., Patterson, B. K., Stephen, R., Sacha, J. B., Wu, H. L., Gross, S. A. & Dhody, K., Jan 2021, In: Journal of Translational Autoimmunity. 4, 100083.
Research output: Contribution to journal › Review article › peer-review

Open Access
Genome-wide DNA methylation profiling of peripheral blood reveals an epigenetic signature associated with severe COVID-19
Corley, M. J., Pang, A. P. S., Dody, K., Mudd, P. A., Patterson, B. K., Seethamraju, H., Bram, Y., Peluso, M. J., Torres, L., Iyer, N. S., Premeaux, T. A., Yeung, S. T., Chandar, V., Borczuk, A., Schwartz, R. E., Henrich, T. J., Deeks, S. G., Sacha, J. B. & Ndhlovu, L. C., 2021, (Accepted/In press) In: Journal of Leukocyte Biology.
Research output: Contribution to journal › Article › peer-review
1 Scopus citations
Modified Adenovirus Prime-Protein Boost Clade C HIV Vaccine Strategy Results in Reduced Viral DNA in Blood and Tissues Following Tier 2 SHIV Challenge
Malherbe, D. C., Vang, L., Mendy, J., Barnette, P. T., Spencer, D. A., Reed, J., Kareko, B. W., Sather, D. N., Pandey, S., Wibmer, C. K., Robins, H., Fuller, D. H., Park, B., Lakhashe, S. K., Wilson, J. M., Axthelm, M. K., Ruprecht, R. M., Moore, P. L., Sacha, J. B., Hessell, A. J. & 2 others, Alexander, J. & Haigwood, N. L., Feb 15 2021, In: Frontiers in immunology. 11, 626464.
Research output: Contribution to journal › Article › peer-review

Open Access
1 Scopus citations
Terumo spectra optia leukapheresis of cynomolgus macaques for hematopoietic stem cell and T cell collection
Wu, H. L., Greene, J. M., Swanson, T., Shriver-Munsch, C., Armantrout, K., Weber, W. C., Bateman, K. B., Maier, N. M., Northrup, M., Legasse, A. W., Moats, C., Axthelm, M. K., Smedley, J., Maziarz, R. T., Martin, L. D., Hobbs, T., Burwitz, B. J. & Sacha, J. B., Feb 2021, In: Journal of Clinical Apheresis. 36, 1, p. 67-77 11 p.
Research output: Contribution to journal › Article › peer-review