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Dive into the research topics where Jonah Sacha is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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An IL-15 superagonist approach to clear the latent viral reservoir
Project: Research project
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Identifying endogenous retrovirus T cell targets in SIV-infected macaques
Project: Research project
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A Solid-Phase, Long-Acting CCR5 Monoclonal Antibody for HIV Transmission
Project: Research project
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Effect of obesity on HIV pathogenesis, antiretroviral therapy, and metabolic comorbidities
Kievit, P., Sacha, J., Kievit, P. & Sacha, J.
Project: Research project
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Impact of retroviral infection on non-classical, mycobacteria-specific T cells.
Hansen, S., Sacha, J., Hansen, S. & Sacha, J.
Project: Research project
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Long-term hepatitis B virus infection of rhesus macaques requires suppression of host immunity
Biswas, S., Rust, L. N., Wettengel, J. M., Yusova, S., Fischer, M., Carson, J. N., Johnson, J., Wei, L., Thode, T., Kaadige, M. R., Sharma, S., Agbaria, M., Bimber, B. N., Tu, T., Protzer, U., Ploss, A., Smedley, J. V., Golomb, G., Sacha, J. B. & Burwitz, B. J., Dec 2022, In: Nature communications. 13, 1, 2995.Research output: Contribution to journal › Article › peer-review
Open Access -
Suppression of human and simian immunodeficiency virus replication with the CCR5-specific antibody Leronlimab in two species
Chang, X. L., Reed, J. S., Webb, G. M., Wu, H. L., Le, J., Bateman, K. B., Greene, J. M., Pessoa, C., Waytashek, C., Weber, W. C., Hwang, J., Fischer, M., Moats, C., Shiel, O., Bochart, R. M., Crank, H., Siess, D., Giobbi, T., Torgerson, J., Agnor, R., & 14 others, Mar 2022, In: PLoS pathogens. 18, 3, e1010396.Research output: Contribution to journal › Article › peer-review
Open Access -
Antibody-based CCR5 blockade protects Macaques from mucosal SHIV transmission
Chang, X. L., Webb, G. M., Wu, H. L., Greene, J. M., Abdulhaqq, S., Bateman, K. B., Reed, J. S., Pessoa, C., Weber, W. C., Maier, N., Chew, G. M., Gilbride, R. M., Gao, L., Agnor, R., Giobbi, T., Torgerson, J., Siess, D., Burnett, N., Fischer, M., Shiel, O., & 13 others, Dec 1 2021, In: Nature communications. 12, 1, 3343.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
CCR5 inhibition in critical COVID-19 patients decreases inflammatory cytokines, increases CD8 T-cells, and decreases SARS-CoV2 RNA in plasma by day 14
Patterson, B. K., Seethamraju, H., Dhody, K., Corley, M. J., Kazempour, K., Lalezari, J., Pang, A. P. S., Sugai, C., Mahyari, E., Francisco, E. B., Pise, A., Rodrigues, H., Wu, H. L., Webb, G. M., Park, B. S., Kelly, S., Pourhassan, N., Lelic, A., Kdouh, L., Herrera, M., & 10 others, Feb 2021, In: International Journal of Infectious Diseases. 103, p. 25-32 8 p.Research output: Contribution to journal › Article › peer-review
Open Access43 Scopus citations -
CCR5 Receptor Occupancy Analysis Reveals Increased Peripheral Blood CCR5+CD4+ T Cells Following Treatment With the Anti-CCR5 Antibody Leronlimab
Chang, X. L., Wu, H. L., Webb, G. M., Tiwary, M., Hughes, C., Reed, J. S., Hwang, J., Waytashek, C., Boyle, C., Pessoa, C., Sylwester, A. W., Morrow, D., Belica, K., Fischer, M., Kelly, S., Pourhassan, N., Bochart, R. M., Smedley, J., Recknor, C. P., Hansen, S. G., & 1 others, Nov 19 2021, In: Frontiers in immunology. 12, 794638.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations