Jacob Raber

Professor

  • 8513 Citations
  • 42 h-Index
1976 …2018
If you made any changes in Pure these will be visible here soon.

Research Output 1989 2018

  • 8513 Citations
  • 42 h-Index
  • 202 Article
  • 4 Chapter
  • 2 Review article
  • 1 Comment/debate
Filter
Article
2018
3 Citations

Blood phenylalanine reduction corrects CNS dopamine and serotonin deficiencies and partially improves behavioral performance in adult phenylketonuric mice

Winn, S. R., Scherer, T., Thöny, B., Ying, M., Martinez, A., Weber, S., Raber, J. & Harding, C. O., Jan 1 2018, In : Molecular Genetics and Metabolism. 123, 1, p. 6-20 15 p.

Research output: Contribution to journalArticle

Prefabricated roofs
Phenylalanine
Dopamine
Serotonin
Central Nervous System

Detrimental effects of helium ion irradiation on cognitive performance and cortical levels of MAP-2 in B6D2F1 mice

Raber, J., Torres, E. R. S., Akinyeke, T., Lee, J., Weber Boutros, S. J., Turker, M. S. & Kronenberg, A., Apr 20 2018, In : International Journal of Molecular Sciences. 19, 4, 1247

Research output: Contribution to journalArticle

Helium
Microtubule-Associated Proteins
helium ions
Apolipoproteins E
Ion bombardment

Dlx1/2 and Otp coordinate the production of hypothalamic GHRH- and AgRP-neurons

Lee, B., Kim, J., An, T., Kim, S., Patel, E. M., Raber, J., Lee, S. K., Lee, S. & Lee, J. W., Dec 1 2018, In : Nature Communications. 9, 1, 4377

Research output: Contribution to journalArticle

neurons
Neurons
genes
Genes
homeostasis

Non-estrogenic Xanthohumol Derivatives Mitigate Insulin Resistance and Cognitive Impairment in High-Fat Diet-induced Obese Mice

Miranda, C. L. , Johnson, L. A. , De Montgolfier, O. , Elias, V. D. , Ullrich, L. S. , Hay, J. J. , Paraiso, I. L. , Choi, J. , Reed, R. L. , Revel, J. S. , Kioussi, C. , Bobe, G. , Iwaniec, U. T. , Turner, R. T. , Katzenellenbogen, B. S. , Katzenellenbogen, J. A. , Blakemore, P. R. , Gombart, A. F. , Maier, C. S. , Raber, J. & 1 others Stevens, J. F., Dec 1 2018, In : Scientific Reports. 8, 1, 613

Research output: Contribution to journalArticle

Obese Mice
High Fat Diet
Insulin Resistance
xanthohumol
Cognitive Dysfunction
2017
1 Citations

28Si total body irradiation injures bone marrow hematopoietic stem cells via induction of cellular apoptosis

Chang, J., Feng, W., Wang, Y., Allen, A. R., Turner, J., Stewart, B., Raber, J., Hauer-Jensen, M., Zhou, D. & Shao, L., May 1 2017, In : Life Sciences in Space Research. 13, p. 39-44 6 p.

Research output: Contribution to journalArticle

bone marrow
stem cells
Whole-Body Irradiation
apoptosis
Hematopoietic Stem Cells
5 Citations

Apolipoprotein E4 and Insulin Resistance Interact to Impair Cognition and Alter the Epigenome and Metabolome

Johnson, L. A., Torres, E. R. S., Impey, S., Stevens, J. F. & Raber, J., Mar 8 2017, In : Scientific Reports. 7, 43701

Research output: Contribution to journalArticle

Apolipoprotein E4
Metabolome
Cognition
Insulin Resistance
High Fat Diet
2 Citations

Apolipoprotein E4 mediates insulin resistance-associated cerebrovascular dysfunction and the post-prandial response

Johnson, L. A., Torres, E. R., Weber Boutros, S., Patel, E., Akinyeke, T., Alkayed, N. J. & Raber, J., Jan 1 2017, (Accepted/In press) In : Journal of Cerebral Blood Flow and Metabolism.

Research output: Contribution to journalArticle

Apolipoprotein E4
High Fat Diet
Meals
Insulin Resistance
Protein Isoforms

Assessment of mutations in KCNN2 and ZNF135 to patient neurological symptoms

Raghuram, V., Weber, S., Raber, J., Chen, D. H., Bird, T. D., Maylie, J. & Adelman, J. P., 2017, In : NeuroReport. 28, 7, p. 375-379 5 p.

Research output: Contribution to journalArticle

Mutation
Nonsense Codon
Genes
Exome
Brain
2 Citations

Bi-directional and shared epigenomic signatures following proton and 56Fe irradiation

Impey, S., Jopson, T., Pelz, C., Tafessu, A., Fareh, F., Zuloaga, D., Marzulla, T., Riparip, L. K., Stewart, B., Rosi, S., Turker, M. S. & Raber, J., Dec 1 2017, In : Scientific Reports. 7, 1, 10227

Research output: Contribution to journalArticle

DNA Methylation
Epigenomics
Protons
Gene Ontology
Astronauts
6 Citations

CD44 transmembrane receptor and hyaluronan regulate adult hippocampal neural stem cell quiescence and differentiation

Su, W., Foster, S. C., Xing, R., Feistel, K., Olsen, R. H. J., Acevedo, S. F., Raber, J. & Sherman, L. S., Mar 17 2017, In : Journal of Biological Chemistry. 292, 11, p. 4434-4445 12 p.

Research output: Contribution to journalArticle

CD44 Antigens
Neural Stem Cells
Hyaluronic Acid
Stem cells
Cell Differentiation
2 Citations

Effects of adolescent methamphetamine and nicotine exposure on behavioral performance and MAP-2 immunoreactivity in the nucleus accumbens of adolescent mice

Buck, J. M., Morris, A. S., Weber, S. J., Raber, J. & Siegel, J. A., Apr 14 2017, In : Behavioural Brain Research. 323, p. 78-85 8 p.

Research output: Contribution to journalArticle

Methamphetamine
Nucleus Accumbens
Nicotine
Corticosterone
Brain
1 Citations

Enhanced cued fear memory following post-training whole body irradiation of 3-month-old mice

Olsen, R. H. J., Weber, S. J., Akinyeke, T. & Raber, J., Feb 15 2017, In : Behavioural Brain Research. 319, p. 181-187 7 p.

Research output: Contribution to journalArticle

Whole-Body Irradiation
Fear
Body Weight Changes
Body Weight
X-Rays
3 Citations

Genetic inhibition of Anaplastic Lymphoma Kinase rescues cognitive impairments in Neurofibromatosis 1 mutant mice

Weiss, J. B., Weber, S. J., Torres, E. R. S., Marzulla, T. & Raber, J., Mar 15 2017, In : Behavioural Brain Research. 321, p. 148-156 9 p.

Research output: Contribution to journalArticle

Neurofibromatosis 1
Drosophila
Sleep
Learning
anaplastic lymphoma kinase
7 Citations

Neuroinflammatory and cognitive consequences of combined radiation and immunotherapy in a novel preclinical model

McGinnis, G. J., Friedman, D., Young, K. H., Torres, E. R. S., Thomas, C. R., Gough, M. J. & Raber, J., 2017, In : Oncotarget. 8, 6, p. 9155-9173 19 p.

Research output: Contribution to journalArticle

Immunotherapy
Radiation
Neoplasms
Radiotherapy
Inbred C57BL Mouse
Apolipoprotein E2
Apolipoprotein E4
Reactive Oxygen Species
Pharmacology
Apolipoproteins E
2 Citations

Pharmacological inhibition of Anaplastic Lymphoma Kinase rescues spatial memory impairments in Neurofibromatosis 1 mutant mice

Weiss, J. B., Weber, S., Marzulla, T. & Raber, J., Aug 14 2017, In : Behavioural Brain Research. 332, p. 337-342 6 p.

Research output: Contribution to journalArticle

Neurofibromatosis 1
Pharmacology
Neurofibromatoses
Diptera
Drosophila
2016
12 Citations

Amelioration of Metabolic Syndrome-Associated Cognitive Impairments in Mice via a Reduction in Dietary Fat Content or Infusion of Non-Diabetic Plasma

Johnson, L. A., Zuloaga, K. L., Kugelman, T. L., Mader, K. S., Morré, J. T., Zuloaga, D. G., Weber, S., Marzulla, T., Mulford, A., Button, D., Lindner, J. R., Alkayed, N. J., Stevens, J. F. & Raber, J., Jan 1 2016, In : EBioMedicine. 3, p. 26-42 17 p.

Research output: Contribution to journalArticle

Dietary Fats
Nutrition
Plasmas
Data storage equipment
Medical problems
1 Citations

Chronic methamphetamine exposure prior to middle cerebral artery occlusion increases infarct volume and worsens cognitive injury in Male mice

Zuloaga, D. G., Wang, J., Weber, S., Mark, G. P., Murphy, S. J. & Raber, J., Mar 28 2016, (Accepted/In press) In : Metabolic Brain Disease. p. 1-7 7 p.

Research output: Contribution to journalArticle

Methamphetamine
Middle Cerebral Artery Infarction
Wounds and Injuries
Reperfusion
Stroke
9 Citations

Densely ionizing radiation affects DNA methylation of selective LINE-1 elements

Prior, S., Miousse, I. R., Nzabarushimana, E., Pathak, R., Skinner, C., Kutanzi, K. R., Allen, A. R., Raber, J., Tackett, A. J., Hauer-Jensen, M., Nelson, G. A. & Koturbash, I., Oct 1 2016, In : Environmental Research. 150, p. 470-481 12 p.

Research output: Contribution to journalArticle

Long Interspersed Nucleotide Elements
Ionizing radiation
methylation
DNA Methylation
Ionizing Radiation
3 Citations

Effect of behavioral testing on spine density of basal dendrites in the CA1 region of the hippocampus modulated by 56Fe irradiation

Raber, J., Allen, A. R., Weber, S., Chakraborti, A., Sharma, S. & Fike, J. R., Apr 1 2016, In : Behavioural Brain Research. 302, p. 263-268 6 p.

Research output: Contribution to journalArticle

Dendrites
Hippocampus
Spine
Exploratory Behavior
Aptitude
1 Citations

Effects of alcohol on c-Myc protein in the brain

Akinyeke, T., Weber, S. J., Davenport, A. T., Baker, E. J., Daunais, J. B. & Raber, J., Aug 1 2016, (Accepted/In press) In : Behavioural Brain Research.

Research output: Contribution to journalArticle

Proto-Oncogene Proteins c-myc
Alcoholism
Alcohols
Brain
Methamphetamine
18 Citations

Effects of Proton and Combined Proton and 56Fe Radiation on the Hippocampus

Raber, J., Allen, A. R., Sharma, S., Allen, B., Rosi, S., Olsen, R. H. J., Davis, M. J., Eiwaz, M., Fike, J. R. & Nelson, G. A., Jan 1 2016, In : Radiation Research. 185, 1, p. 20-30 11 p.

Research output: Contribution to journalArticle

hippocampus
mice
Protons
Hippocampus
Radiation
5 Citations

Fetal domoic acid exposure affects lateral amygdala neurons, diminishes social investigation and alters sensory-motor gating

Zuloaga, D. G., Lahvis, G. P., Mills, B., Pearce, H. L., Turner, J. & Raber, J., Mar 1 2016, In : NeuroToxicology. 53, p. 132-140 9 p.

Research output: Contribution to journalArticle

Sensory Gating
Amygdala
Neurons
Parvalbumins
domoic acid
4 Citations
Apolipoprotein E4
Fear
Reactive Oxygen Species
Anxiety
Genotype
13 Citations

High fat diet-induced diabetes in mice exacerbates cognitive deficit due to chronic hypoperfusion

Zuloaga, K. L., Johnson, L. A., Roese, N. E., Marzulla, T., Zhang, W., Nie, X., Alkayed, F. N., Hong, C., Grafe, M. R., Pike, M. M., Raber, J. & Alkayed, N. J., Jul 1 2016, In : Journal of Cerebral Blood Flow and Metabolism. 36, 7, p. 1257-1270 14 p.

Research output: Contribution to journalArticle

Cerebrovascular Circulation
High Fat Diet
Blood Vessels
Cognition
Fear
5 Citations

Immediate and lasting effects of chronic daily methamphetamine exposure on activation of cells in hypothalamic-pituitary-adrenal axis-associated brain regions

Zuloaga, D. G., Johnson, L. A., Weber, S. & Raber, J., Feb 1 2016, In : Psychopharmacology. 233, 3, p. 381-392 12 p.

Research output: Contribution to journalArticle

Methamphetamine
Brain
Septal Nuclei
Substance Withdrawal Syndrome
Amygdala
3 Citations

Ion mobility-enhanced MSE-based label-free analysis reveals effects of low-dose radiation post contextual fear conditioning training on the mouse hippocampal proteome

Huang, L., Wickramasekara, S. I., Akinyeke, T., Stewart, B. S., Jiang, Y., Raber, J. & Maier, C. S., May 17 2016, In : Journal of Proteomics. 140, p. 24-36 13 p.

Research output: Contribution to journalArticle

Proteome
Dosimetry
Fear
Labels
Ions
4 Citations

Metabolic shifts toward fatty-acid usage and increased thermogenesis are associated with impaired adipogenesis in mice expressing human APOE4

Arbones-Mainar, J. M., Johnson, L. A., Torres-Perez, E., Garcia, A. E., Perez-Diaz, S., Raber, J. & Maeda, N., Jun 7 2016, (Accepted/In press) In : International Journal of Obesity.

Research output: Contribution to journalArticle

Adipogenesis
Thermogenesis
Apolipoproteins E
Fatty Acids
Lipids

Mitigating effect of EUK-207 on radiation-induced cognitive impairments

Raber, J., Davis, M. J., Pfankuch, T., Rosenthal, R., Doctrow, S. R. & Moulder, J. E., Sep 14 2016, (Accepted/In press) In : Behavioural Brain Research.

Research output: Contribution to journalArticle

Radiation
Terrorism
Radiation Injuries
Wounds and Injuries
Radiodermatitis
5 Citations

Post-training gamma irradiation-enhanced contextual fear memory associated with reduced neuronal activation of the infralimbic cortex

Kugelman, T., Zuloaga, D. G., Weber, S. & Raber, J., Feb 1 2016, In : Behavioural Brain Research. 298, p. 1-11 11 p.

Research output: Contribution to journalArticle

Fear
Brain
Learning
Radioactive Hazard Release
Nuclear Weapons
11 Citations

Proton irradiation induces persistent and tissue-specific DNA methylation changes in the left ventricle and hippocampus

Impey, S., Pelz, C., Tafessu, A., Marzulla, T., Turker, M. S. & Raber, J., 2016, In : BMC Genomics. 17, 1, 273

Research output: Contribution to journalArticle

DNA Methylation
5-Methylcytosine
Heart Ventricles
Protons
Hippocampus
6 Citations

Short- and long-term effects of 56Fe irradiation on cognition and hippocampal DNA methylation and gene expression

Impey, S., Jopson, T., Pelz, C., Tafessu, A., Fareh, F., Zuloaga, D., Marzulla, T., Riparip, L. K., Stewart, B., Rosi, S., Turker, M. S. & Raber, J., Oct 24 2016, In : BMC Genomics. 17, 1, 825

Research output: Contribution to journalArticle

DNA Methylation
Cognition
Gene Expression
Ions
Epigenomics
2015
7 Citations

16Oxygen irradiation enhances cued fear memory in B6D2F1 mice

Raber, J., Marzulla, T., Kronenberg, A. & Turker, M. S., Nov 1 2015, In : Life Sciences in Space Research. 7, p. 61-65 5 p.

Research output: Contribution to journalArticle

fear
Fear
mice
irradiation
Oxygen
14 Citations

28Silicon Irradiation Impairs Contextual Fear Memory in B6D2F1 Mice

Raber, J., Marzulla, T., Stewart, B., Kronenberg, A. & Turker, M. S., Jun 1 2015, In : Radiation Research. 183, 6, p. 708-712 5 p.

Research output: Contribution to journalArticle

fear
Silicon
Fear
mice
extraterrestrial radiation
12 Citations

56Fe Irradiation Alters Spine Density and Dendritic Complexity in the Mouse Hippocampus

Allen, A. R., Raber, J., Chakraborti, A., Sharma, S. & Fike, J. R., Dec 1 2015, In : Radiation Research. 184, 6, p. 586-594 9 p.

Research output: Contribution to journalArticle

hippocampus
Dendritic Spines
spine
mice
Linear Energy Transfer
16 Citations

ApoE2 Exaggerates PTSD-Related Behavioral, Cognitive, and Neuroendocrine Alterations

Johnson, L. A., Zuloaga, D. G., Bidiman, E., Marzulla, T., Weber, S., Wahbeh, H. & Raber, J., Sep 14 2015, In : Neuropsychopharmacology. 40, 10, p. 2443-2453 11 p.

Research output: Contribution to journalArticle

Apolipoprotein E2
Post-Traumatic Stress Disorders
Apolipoproteins E
Veterans
Alzheimer Disease
11 Citations

Combined exposure to protons and 56Fe leads to overexpression of Il13 and reactivation of repetitive elements in the mouse lung

Nzabarushimana, E., Prior, S., Miousse, I. R., Pathak, R., Allen, A. R., Latendresse, J., Olsen, R. H. J., Raber, J., Hauer-Jensen, M., Nelson, G. A. & Koturbash, I., Nov 1 2015, In : Life Sciences in Space Research. 7, p. 1-8 8 p.

Research output: Contribution to journalArticle

Interleukin-13
reactivation
lungs
mice
Protons
3 Citations

Early gelatinase activity is not a determinant of long-term recovery after traumatic brain injury in the immature mouse

Semple, B. D., Noble-Haeusslein, L. J., Gooyit, M., Tercovich, K. G., Peng, Z., Nguyen, T. T., Schroeder, V. A., Suckow, M. A., Chang, M., Raber, J. & Trivedi, A., Nov 1 2015, In : PLoS One. 10, 11, e0143386

Research output: Contribution to journalArticle

Gelatinases
Brain
immatures
Matrix Metalloproteinase 2
brain
2 Citations

Enhanced functional connectivity involving the ventromedial hypothalamus following methamphetamine exposure

Zuloaga, D. G., Iancu, O. D., Weber, S., Etzel, D., Marzulla, T., Stewart, B., Allen, C. N. & Raber, J., 2015, In : Frontiers in Neuroscience. 9, SEP, 326

Research output: Contribution to journalArticle

Methamphetamine
Hypothalamus
Brain
Light
Middle Hypothalamus
17 Citations

Methamphetamine and the hypothalamic-pituitary-adrenal axis

Zuloaga, D. G., Jacosbskind, J. S. & Raber, J., 2015, In : Frontiers in Neuroscience. 9, MAY, p. 178 1 p.

Research output: Contribution to journalArticle

Methamphetamine
Anxiety
Depression
Recurrence
Brain
15 Citations

Neurobehavioral and Imaging Correlates of Hippocampal Atrophy in a Mouse Model of Vascular Cognitive Impairment

Zuloaga, K. L., Zhang, W., Yeiser, L. A., Stewart, B., Kukino, A., Nie, X., Roese, N. E., Grafe, M. R., Pike, M. M., Raber, J. & Alkayed, N. J., Jun 5 2015, In : Translational Stroke Research. 6, 5, p. 390-398 9 p.

Research output: Contribution to journalArticle

Atrophy
Blood Vessels
Common Carotid Artery
Cerebrovascular Circulation
Magnetic Resonance Imaging
5 Citations
Cognition
Primates
Rodentia
Language
Recognition (Psychology)
4 Citations
Metabotropic Glutamate Receptors
Glutamate Receptors
Anxiety Disorders
Anxiety
Synaptic Transmission
41 Citations

Removal of perineuronal nets in the medial prefrontal cortex impairs the acquisition and reconsolidation of a cocaine-induced conditioned place preference memory

Slaker, M., Churchill, L., Todd, R. P., Blacktop, J. M., Zuloaga, D. G., Raber, J., Darling, R. A., Brown, T. E. & Sorg, B. A., 2015, In : Journal of Neuroscience. 35, 10, p. 4190-4202 13 p.

Research output: Contribution to journalArticle

Prefrontal Cortex
Cocaine
Pyramidal Cells
Parvalbumins
Interneurons
7 Citations

Sex, but not Apolipoprotein E Polymorphism, Differences in Spatial Performance in Young Adults

Yasen, A. L., Raber, J., Miller, J. K. & Piper, B. J., Nov 1 2015, In : Archives of Sexual Behavior. 44, 8, p. 2219-2226 8 p.

Research output: Contribution to journalArticle

Apolipoproteins E
Young Adult
Islands
Genotype
Individuality
3 Citations
fear
conditioning
ion irradiation
Fear
mice
18 Citations

Whole-body proton irradiation causes long-term damage to hematopoietic stem cells in mice

Chang, J., Feng, W., Wang, Y., Luo, Y., Allen, A. R., Koturbash, I., Turner, J., Stewart, B., Raber, J., Hauer-Jensen, M., Zhou, D. & Shao, L., Feb 1 2015, In : Radiation Research. 183, 2, p. 240-248 9 p.

Research output: Contribution to journalArticle

proton irradiation
stem cells
Whole-Body Irradiation
Hematopoietic Stem Cells
mice
2014
23 Citations

28Silicon radiation-induced enhancement of synaptic plasticity in the hippocampus of naïve and cognitively tested mice

Raber, J., Rudobeck, E., Campbell-Beachler, M., Allen, A. R., Allen, B., Rosi, S., Nelson, G. A., Ramachandran, S., Turner, J., Fike, J. R. & Vlkolinsky, R., 2014, In : Radiation Research. 181, 4, p. 362-368 7 p.

Research output: Contribution to journalArticle

hippocampus
Neuronal Plasticity
plastic properties
mice
Hippocampus
21 Citations

Apolipoprotein E-low density lipoprotein receptor interaction affects spatial memory retention and brain ApoE levels in an isoform-dependent manner

Johnson, L. A., Olsen, R. H. J., Merkens, L. S., DeBarber, A., Steiner, R. D., Sullivan, P. M., Maeda, N. & Raber, J., Apr 2014, In : Neurobiology of Disease. 64, p. 150-162 13 p.

Research output: Contribution to journalArticle

LDL Receptors
Apolipoproteins E
Protein Isoforms
Brain
Apolipoprotein E2
14 Citations

CD44 is required for spatial memory retention and sensorimotor functions

Raber, J., Olsen, R. H. J., Su, W., Foster, S., Xing, R., Acevedo, S. F. & Sherman, L. S., Sep 16 2014, In : Behavioural Brain Research. 275, p. 146-149 4 p.

Research output: Contribution to journalArticle

Genotype
CD44 Antigens
Spatial Memory
Retention (Psychology)
Neural Stem Cells