Ian Martin

Assistant Professor

  • 1602 Citations
  • 20 h-Index
20032018

Research output per year

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Research Output

2018

Genetic modifiers of neurodegeneration in a drosophila model of parkinson’s disease

Lavoy, S., Chittoor-Vinod, V. G., Chow, C. Y. & Martin, I., Aug 1 2018, In : Genetics. 209, 4, p. 1345-1356 12 p.

Research output: Contribution to journalArticle

11 Scopus citations
2017

Protein Translation in Parkinson's Disease

Kim, J. W., Abalde-Atristain, L., Jia, H., Martin, I., Dawson, T. M. & Dawson, V. L., Jan 6 2017, Parkinson's Disease: Molecular Mechanisms Underlying Pathology. Elsevier Inc., p. 245-279 35 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations
2016

A glucocerebrosidase chaperone to ward off Parkinson's disease

Martin, I., Aug 10 2016, In : Science Translational Medicine. 8, 351, 351ec128.

Research output: Contribution to journalEditorial

Alzheimer's medicine: β-Amyloid takes a siP

Martin, I., Dec 14 2016, In : Science Translational Medicine. 8, 369, 369ec200.

Research output: Contribution to journalComment/debate

An old drug auditions for a new leading role

Martin, I., Jun 29 2016, In : Science Translational Medicine. 8, 345, 345ec105.

Research output: Contribution to journalComment/debate

Caspase-2: Divide and conquer

Martin, I., Nov 2 2016, In : Science Translational Medicine. 8, 363, 363ec176.

Research output: Contribution to journalComment/debate

Decoding Parkinson's Disease Pathogenesis: The Role of Deregulated mRNA Translation

Martin, I., Mar 30 2016, In : Journal of Parkinson's Disease. 6, 1, p. 17-27 11 p.

Research output: Contribution to journalReview article

1 Scopus citations

Desferrioxamine passes the sniff test

Martin, I., Apr 6 2016, In : Science Translational Medicine. 8, 333, ec55.

Research output: Contribution to journalEditorial

LRRK2 pathobiology in Parkinson's disease – virtual inclusion

Martin, I., Kim, J. W., Dawson, V. L. & Dawson, T. M., Oct 1 2016, In : Journal of Neurochemistry. p. 75-76 2 p.

Research output: Contribution to journalComment/debate

2 Scopus citations

Parkinson disease: Insect screens for PD therapies-keep the flies in

Martin, I. & Chittoor, V. G., Jun 1 2016, In : Nature Reviews Neurology. 12, 6, p. 318-319 2 p.

Research output: Contribution to journalShort survey

2 Scopus citations

Remote control of transplanted neurons in Parkinson's disease

Martin, I., May 18 2016, In : Science Translational Medicine. 8, 339, 339ec81.

Research output: Contribution to journalComment/debate

2015

A novel cholinergic action of alcohol and the development of tolerance to that effect in Caenorhabditis elegans

Hawkins, E. G., Martin, I., Kondo, L. M., Judy, M. E., Brings, V. E., Chan, C. L., Blackwell, G. G., Bettinger, J. C. & Davies, A. G., Jan 1 2015, In : Genetics. 199, 1, p. 135-149 15 p.

Research output: Contribution to journalArticle

4 Scopus citations

LRRK2 G2019S transgenic mice display increased susceptibility to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-mediated neurotoxicity

Karuppagounder, S. S., Xiong, Y., Lee, Y., Lawless, M. C., Kim, D., Nordquist, E., Martin, I., Ge, P., Brahmachari, S., Jhaldiyal, A., Kumar, M., Andrabi, S. A., Dawson, T. M. & Dawson, V. L., Oct 31 2015, (Accepted/In press) In : Journal of Chemical Neuroanatomy.

Research output: Contribution to journalArticle

16 Scopus citations
2014

Abberant protein synthesis in G2019S LRRK2 drosophila parkinson disease-related phenotypes

Martin, I., Abalde-Atristain, L., Kim, J. W., Dawson, T. M. & Dawson, V. L., Jan 1 2014, In : Fly. 8, 3, p. 165-169 5 p.

Research output: Contribution to journalArticle

11 Scopus citations

LRRK2 pathobiology in Parkinson's disease

Martin, I., Kim, J. W., Dawson, V. L. & Dawson, T. M., Dec 2014, In : Journal of Neurochemistry. 131, 5, p. 554-565 12 p.

Research output: Contribution to journalReview article

77 Scopus citations

Paraquat exposure and Sod2 knockdown have dissimilar impacts on the Drosophila melanogaster carbonylated protein proteome

Narayanasamy, S. K., Simpson, D. C., Martin, I., Grotewiel, M. & Gronert, S., Nov 1 2014, In : Proteomics. 14, 21-22, p. 2566-2577 12 p.

Research output: Contribution to journalArticle

3 Scopus citations

Ribosomal protein s15 phosphorylation mediates LRRK2 neurodegeneration in parkinson's disease

Martin, I., Kim, J. W., Lee, B. D., Kang, H. C., Xu, J. C., Jia, H., Stankowski, J., Kim, M. S., Zhong, J., Kumar, M., Andrabi, S. A., Xiong, Y., Dickson, D. W., Wszolek, Z. K., Pandey, A., Dawson, T. M. & Dawson, V. L., Apr 10 2014, In : Cell. 157, 2, p. 472-485 14 p.

Research output: Contribution to journalArticle

133 Scopus citations
2012

Chloride intracellular channels modulate acute ethanol behaviors in Drosophila, Caenorhabditis elegans and mice

Bhandari, P., Hill, J. S., Farris, S. P., Costin, B., Martin, I., Chan, C. L., Alaimo, J. T., Bettinger, J. C., Davies, A. G., Miles, M. F. & Grotewiel, M., Jun 1 2012, In : Genes, Brain and Behavior. 11, 4, p. 387-397 11 p.

Research output: Contribution to journalArticle

36 Scopus citations
2011

Recent advances in the genetics of parkinson's disease

Martin, I., Dawson, V. L. & Dawson, T. M., Jul 13 2011, In : Annual Review of Genomics and Human Genetics. 12, p. 301-325 25 p.

Research output: Contribution to journalArticle

267 Scopus citations

The New York Stem Cell Foundation: Fifth Annual Translational Stem Cell Research Conference

Marshall, C., Kai Wang, G., Cimetta, E., Talchai, C., Egli, D., Shim, J. W., Martin, I., Ahmad, F., Sproul, A., Chen, T., Fossati, V., Mckeon, D., Smith, K. & Solomon, S. L., May 2011, In : Annals of the New York Academy of Sciences. 1226, 1, p. 1-13 13 p.

Research output: Contribution to journalArticle

1 Scopus citations
2010

The impact of genetic research on our understanding of Parkinson's disease

Martin, I., Dawson, V. L. & Dawson, T. M., Jan 1 2010, Progress in Brain Research. C ed. Elsevier B.V., p. 21-41 21 p. (Progress in Brain Research; vol. 183, no. C).

Research output: Chapter in Book/Report/Conference proceedingChapter

23 Scopus citations
2009

A forward genetic screen in Drosophila implicates insulin signaling in age-related locomotor impairment

Jones, M. A., Gargano, J. W., Rhodenizer, D., Martin, I., Bhandari, P. & Grotewiel, M., Aug 1 2009, In : Experimental Gerontology. 44, 8, p. 532-540 9 p.

Research output: Contribution to journalArticle

20 Scopus citations

Manipulation of Sod1 expression ubiquitously, but not in the nervous system or muscle, impacts age-related parameters in Drosophila

Martin, I., Jones, M. A. & Grotewiel, M., Jul 7 2009, In : FEBS Letters. 583, 13, p. 2308-2314 7 p.

Research output: Contribution to journalArticle

25 Scopus citations

Multiple measures of functionality exhibit progressive decline in a parallel, stochastic fashion in Drosophila Sod2 null mutants

Piazza, N., Hayes, M., Martin, I., Duttaroy, A., Grotewiel, M. & Wessells, R., Jan 19 2009, In : Biogerontology. 10, 5, p. 637-648 12 p.

Research output: Contribution to journalArticle

14 Scopus citations

Sod2 knockdown in the musculature has whole-organism consequences in Drosophila

Martin, I., Jones, M. A., Rhodenizer, D., Zheng, J., Warrick, J. M., Seroude, L. & Grotewiel, M., Sep 15 2009, In : Free Radical Biology and Medicine. 47, 6, p. 803-813 11 p.

Research output: Contribution to journalArticle

29 Scopus citations
2008

Genetic and environmental factors impact age-related impairment of negative geotaxis in Drosophila by altering age-dependent climbing speed

Rhodenizer, D., Martin, I., Bhandari, P., Pletcher, S. D. & Grotewiel, M., Aug 1 2008, In : Experimental Gerontology. 43, 8, p. 739-748 10 p.

Research output: Contribution to journalArticle

61 Scopus citations
2007

Dietary restriction alters demographic but not behavioral aging in Drosophila

Bhandari, P., Jones, M. A., Martin, I. & Grotewiel, M. S., Oct 1 2007, In : Aging Cell. 6, 5, p. 631-637 7 p.

Research output: Contribution to journalArticle

32 Scopus citations

Reduced mitochondrial SOD displays mortality characteristics reminiscent of natural aging

Paul, A., Belton, A., Nag, S., Martin, I., Grotewiel, M. S. & Duttaroy, A., Nov 1 2007, In : Mechanisms of Ageing and Development. 128, 11-12, p. 706-716 11 p.

Research output: Contribution to journalArticle

69 Scopus citations
2006

Distinct genetic influences on locomotor senescence in Drosophila revealed by a series of metrical analyses

Martin, I. & Grotewiel, M. S., Sep 1 2006, In : Experimental Gerontology. 41, 9, p. 877-881 5 p.

Research output: Contribution to journalArticle

28 Scopus citations

Oxidative damage and age-related functional declines

Martin, I. & Grotewiel, M. S., May 1 2006, In : Mechanisms of Ageing and Development. 127, 5, p. 411-423 13 p.

Research output: Contribution to journalArticle

115 Scopus citations
2005

A proposed set of descriptors for functional senescence data

Martin, I., Gargano, J. W. & Grotewiel, M. S., Jun 1 2005, In : Aging Cell. 4, 3, p. 161-164 4 p.

Research output: Contribution to journalArticle

10 Scopus citations

Functional senescence in Drosophila melanogaster

Grotewiel, M. S., Martin, I., Bhandari, P. & Cook-Wiens, E., Aug 2005, In : Ageing Research Reviews. 4, 3, p. 372-397 26 p.

Research output: Contribution to journalShort survey

180 Scopus citations

Rapid iterative negative geotaxis (RING): A new method for assessing age-related locomotor decline in Drosophila

Gargano, J. W., Martin, I., Bhandari, P. & Grotewiel, M. S., May 1 2005, In : Experimental Gerontology. 40, 5, p. 386-395 10 p.

Research output: Contribution to journalArticle

195 Scopus citations
2004

Arachidonic acid-induced carbon-centered radicals and phospholipid peroxidation in cyclo-oxygenase-2-transfected PC12 cells

Jiang, J., Borisenko, G. G., Osipov, A., Martin, I., Chen, R., Shvedova, A. A., Sorokin, A., Tyurina, Y. Y., Potapovich, A., Tyurin, V. A., Graham, S. H. & Kagan, V. E., Sep 1 2004, In : Journal of Neurochemistry. 90, 5, p. 1036-1049 14 p.

Research output: Contribution to journalArticle

55 Scopus citations

Ascorbate as a "redox sensor" and protector against irradiation-induced oxidative stress in 32D CL 3 hematopoietic cells and subclones overexpressing human manganese superoxide dismutase

Epperly, M. W., Osipov, A. N., Martin, I., Kawai, K. K., Borisenko, G. G., Tyurina, Y. Y., Jefferson, M., Bernarding, M., Greenberger, J. S. & Kagan, V. E., Mar 2004, In : International Journal of Radiation Oncology Biology Physics. 58, 3, p. 851-861 11 p.

Research output: Contribution to journalArticle

38 Scopus citations

Glutathione propagates oxidative stress triggered by myeloperoxidase in HL-60 cells: Evidence for glutathionyl radical-induced peroxidation of phospholipids and cytotoxicity

Borisenko, G. G., Martin, I., Zhao, Q., Amoseato, A. A., Tyurina, Y. Y. & Kagan, V. E., May 28 2004, In : Journal of Biological Chemistry. 279, 22, p. 23453-23462 10 p.

Research output: Contribution to journalArticle

51 Scopus citations

Nitroxides scavenge myeloperoxidase-catalyzed thiyl radicals in model systems and in cells

Borisenko, G. G., Martin, I., Zhao, Q., Amoscato, A. A. & Kagan, V. E., Aug 4 2004, In : Journal of the American Chemical Society. 126, 30, p. 9221-9232 12 p.

Research output: Contribution to journalArticle

62 Scopus citations
2003

Direct evidence for recycling of myeloperoxidase-catalyzed phenoxyl radicals of a vitamin E homologue, 2,2,5,7,8-pentamethyl-6-hydroxy chromane, by ascorbate/dihydrolipoate in living HL-60 cells

Kagan, V. E., Kuzmenko, A. I., Shvedova, A. A., Kisin, E. R., Li, R., Martin, I., Quinn, P. J., Tyurin, V. A., Tyurina, Y. Y. & Yalowich, J. C., Mar 17 2003, In : Biochimica et Biophysica Acta - General Subjects. 1620, 1-3, p. 72-84 13 p.

Research output: Contribution to journalArticle

30 Scopus citations