Hiroyuki Nakai

Professor, Molecular and Medical Genetics, Molecular Microbiology and Immunology, School of Medicine Distinguished Professor in Molecular Medicine

Professor, Molecular Microbiology & Immunology

Emailnakaih@ohsu.edu

Source: Scopus
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5 Finished

Mechanistic Studies of AAP and Capsid Assembly of AAV Vectors
Nakai, H.
Project: Research project
Gene Therapy for Diabetes
Grompe, M. & Nakai, H.
Project: Research project
In vivo targeting of diabetes-relevant human cell types with rAAV vectors
Grompe, M., Kay, M. & Nakai, H.
National Institutes of Health
9/30/14 → 6/30/19
Project: Research project
AAV capsid functions, immune evasion and neuronal targeting in mice and NHP
Nakai, H.
National Institutes of Health
7/1/14 → 4/30/20
Project: Research project
Vector and host cellular biology in AAV vector transduction in vivo
Nakai, H.
National Institutes of Health
4/1/07 → 7/31/14
Project: Research project

5967 Citations
33 h-Index
73 Article
4 Letter
2 Comment/debate
1 Review article

Adeno-associated virus-binding antibodies detected in cats living in the Northeastern United States lack neutralizing activity
Adachi, K., Dissen, G. A., Lomniczi, A., Xie, Q., Ojeda, S. R. & Nakai, H., Dec 1 2020, In: Scientific Reports. 10, 1, 10073.
Research output: Contribution to journal › Article › peer-review

Open Access
In Vivo Repair of a Protein Underlying a Neurological Disorder by Programmable RNA Editing
Sinnamon, J. R., Kim, S. Y., Fisk, J. R., Song, Z., Nakai, H., Jeng, S., McWeeney, S. K. & Mandel, G., Jul 14 2020, In: Cell Reports. 32, 2, 107878.
Research output: Contribution to journal › Article › peer-review

Open Access
5 Scopus citations
Codon-Optimization of Wild-Type Adeno-Associated Virus Capsid Sequences Enhances DNA Family Shuffling while Conserving Functionality
Cabanes-Creus, M., Ginn, S. L., Amaya, A. K., Liao, S. H. Y., Westhaus, A., Hallwirth, C. V., Wilmott, P., Ward, J., Dilworth, K. L., Santilli, G., Rybicki, A., Nakai, H., Thrasher, A. J., Filip, A. C., Alexander, I. E. & Lisowski, L., Mar 15 2019, In: Molecular Therapy - Methods and Clinical Development. 12, p. 71-84 14 p.
Research output: Contribution to journal › Article › peer-review
6 Scopus citations
A quantitative dot blot assay for AAV titration and its use for functional assessment of the adeno-associated virus assembly-activating proteins
Powers, J. M., Chang, X. L., Song, Z. & Nakai, H., Jun 12 2018, In: Journal of Visualized Experiments. 2018, 136, e56766.
Research output: Contribution to journal › Article › peer-review
1 Scopus citations
Adeno-associated virus (AAV) assembly-activating protein is not an essential requirement for capsid assembly of AAV serotypes 4, 5, and 11
Earley, L. F., Powers, J. M., Adachi, K., Baumgart, J. T., Meyer, N. L., Xie, Q., Chapman, M. S. & Nakai, H., 2017, In: Journal of virology. 91, 3, e01980-16.
Research output: Contribution to journal › Article › peer-review
35 Scopus citations