George Thomas

Associate Professor

  • 6353 Citations
  • 30 h-Index
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  • 4 Similar Profiles
Prostatic Neoplasms Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Prostate Medicine & Life Sciences
Renal Cell Carcinoma Medicine & Life Sciences
Castration Medicine & Life Sciences
Mutation Medicine & Life Sciences
Androgen Receptors Medicine & Life Sciences
Stem Cells Medicine & Life Sciences

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Projects 1997 2018

Inhibiting VHL-positive kidney cancer

Thomas, G.

National Institutes of Health


Project: Research projectResearch Project

Kidney Neoplasms
Renal Cell Carcinoma
STAT3 Transcription Factor


Mori, M. (., Corless, C., Beer, T. (., McWeeney, S., Harrington, C. (., Bagby, G., Druker, B., Sexton, G., Hall, A., Henner, W., Samuels, M. H., Bakke, A., Hoatlin, M., Baetscher, M., Keller, T., Nagalla, S., Magun, B. E., Koop, D. R., Mauro, M. J., Blanke, C. D., Bakke, A., Baetscher, M., Koop, D., Spellman, P., David, L., Coussens, L., Streeter, P., Thomas, G., Mori, M. (., Mori, M. (. & Harrington, C. (.

National Institutes of Health


Project: Research projectCenter Core Grants

Research Personnel
Translational Medical Research

Research Output 1998 2018

  • 6353 Citations
  • 30 h-Index
  • 58 Article
  • 1 Letter

DNA repair gene alterations and PARP inhibitor response in patients with metastatic castration-resistant prostate cancer

Lu, E., Thomas, G. V., Chen, Y., Wyatt, A. W., Lloyd, P., Youngren, J., Quigley, D., Bergan, R., Bailey, S., Beer, T. M., Feng, F. Y., Small, E. J. & Alumkal, J. J., Aug 1 2018, In : JNCCN Journal of the National Comprehensive Cancer Network. 16, 8, p. 933-937 5 p.

Research output: Contribution to journalArticle

DNA Repair
Prostatic Neoplasms
BRCA2 Gene
4 Citations

LSD1 activates a lethal prostate cancer gene network independently of its demethylase function

Sehrawat, A. , Gao, L. , Wang, Y. , Bankhead, A. , McWeeney, S. K. , King, C. J. , Schwartzman, J. , Urrutia, J. , Bisson, W. H. , Coleman, D. J. , Joshi, S. K. , Kim, D. H. , Sampson, D. A. , Weinmann, S. , Kallakury, B. V. S. , Berry, D. L. , Haque, R. , Van Den Eeden, S. K. , Sharma, S. , Bearss, J. & 4 others Beer, T. M., Thomas, G. V., Heiser, L. M. & Alumkal, J. J., May 1 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 18, p. E4179-E4188

Research output: Contribution to journalArticle

Gene Regulatory Networks
Neoplasm Genes
Prostatic Neoplasms

Serum cholesterol levels and tumor growth in a PTEN-null transgenic mouse model of prostate cancer

Allott, E. H., Masko, E. M., Freedland, A. R., Macias, E., Pelton, K., Solomon, K. R., Mostaghel, E. A., Thomas, G. V., Pizzo, S. V., Freeman, M. R. & Freedland, S. J., May 23 2018, (Accepted/In press) In : Prostate Cancer and Prostatic Diseases. p. 1-8 8 p.

Research output: Contribution to journalArticle

Transgenic Mice
Prostatic Neoplasms
23 Citations

Analysis of circulating cell-free DnA identifies multiclonal heterogeneity of BRCA2 reversion mutations associated with resistance to PARP inhibitors

Quigley, D. , Alumkal, J. J. , Wyatt, A. W. , Kothari, V. , Foye, A. , Lloyd, P. , Aggarwal, R. , Kim, W. , Lu, E. , Schwartzman, J. , Beja, K. , Annala, M. , Das, R. , Diolaiti, M. , Pritchard, C. , Thomas, G. , Tomlins, S. , Knudsen, K. , Lord, C. J. , Ryan, C. & 5 others Youngren, J., Beer, T. M., Ashworth, A., Small, E. J. & Feng, F. Y., Sep 1 2017, In : Cancer Discovery. 7, 9, p. 999-1005 7 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Recombinational DNA Repair
DNA Repair
16 Citations

Concordance of Circulating Tumor DNA and Matched Metastatic Tissue Biopsy in Prostate Cancer

Wyatt, A. W., Annala, M., Aggarwal, R., Beja, K., Feng, F., Youngren, J., Foye, A., Lloyd, P., Nykter, M., Beer, T. M., Alumkal, J. J., Thomas, G. V., Reiter, R. E., Rettig, M. B., Evans, C. P., Gao, A. C., Chi, K. N., Small, E. J. & Gleave, M. E., Dec 1 2017, In : Journal of the National Cancer Institute. 109, 12

Research output: Contribution to journalArticle

Castration-Resistant Prostatic Neoplasms
Retinoblastoma Binding Proteins
BRCA2 Protein
Adenomatous Polyposis Coli Protein
DNA Copy Number Variations