George Thomas

Associate Professor

Associate Professor, Knight Cancer Institute

Emailthomasge@ohsu.edu

6215 Citations
30 h-Index

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Prostatic Neoplasms Medicine & Life Sciences

Neoplasms Medicine & Life Sciences

Prostate Medicine & Life Sciences

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Castration Medicine & Life Sciences

Mutation Medicine & Life Sciences

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Stem Cells Medicine & Life Sciences

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Inhibiting VHL-positive kidney cancer

Thomas, G.

National Institutes of Health

4/1/13 → 3/31/18

Project: Research project › Research Project

Kidney Neoplasms

Renal Cell Carcinoma

STAT3 Transcription Factor

Therapeutics

Neoplasms

OREGON CANCER CENTER

Mori, M. (., Corless, C., Beer, T. (., McWeeney, S., Harrington, C. (., Bagby, G., Druker, B., Sexton, G., Hall, A., Henner, W., Samuels, M. H., Bakke, A., Hoatlin, M., Baetscher, M., Keller, T., Nagalla, S., Magun, B. E., Koop, D. R., Mauro, M. J., Blanke, C. D., Bakke, A., Baetscher, M., Koop, D., Spellman, P., David, L., Coussens, L., Streeter, P., Thomas, G., Mori, M. (., Mori, M. (. & Harrington, C. (.

National Institutes of Health

8/1/97 → 6/30/17

Project: Research project › Center Core Grants

Neoplasms

Research

Research Personnel

Biostatistics

Translational Medical Research

Research Output 1998 2018

6215 Citations
30 h-Index
57 Article
1 Letter

2 Citations

LSD1 activates a lethal prostate cancer gene network independently of its demethylase function

Sehrawat, A. , Gao, L. , Wang, Y. , Bankhead, A. , McWeeney, S. K. , King, C. J. , Schwartzman, J. , Urrutia, J. , Bisson, W. H. , Coleman, D. J. , Joshi, S. K. , Kim, D. H. , Sampson, D. A. , Weinmann, S. , Kallakury, B. V. S. , Berry, D. L. , Haque, R. , Van Den Eeden, S. K. , Sharma, S. , Bearss, J. & 4 others Beer, T. M., Thomas, G. V., Heiser, L. M. & Alumkal, J. J. May 1 2018 In : Proceedings of the National Academy of Sciences of the United States of America. 115, 18, p. E4179-E4188

Research output: Contribution to journal › Article

Gene Regulatory Networks

Neoplasm Genes

Lysine

Prostatic Neoplasms

Castration

Serum cholesterol levels and tumor growth in a PTEN-null transgenic mouse model of prostate cancer

Allott, E. H., Masko, E. M., Freedland, A. R., Macias, E., Pelton, K., Solomon, K. R., Mostaghel, E. A., Thomas, G. V., Pizzo, S. V., Freeman, M. R. & Freedland, S. J. May 23 2018 (Accepted/In press) In : Prostate Cancer and Prostatic Diseases. p. 1-8 8 p.

Research output: Contribution to journal › Article

Transgenic Mice

Prostatic Neoplasms

Cholesterol

Growth

Serum

15 Citations

Analysis of circulating cell-free DnA identifies multiclonal heterogeneity of BRCA2 reversion mutations associated with resistance to PARP inhibitors

Quigley, D. , Alumkal, J. J. , Wyatt, A. W. , Kothari, V. , Foye, A. , Lloyd, P. , Aggarwal, R. , Kim, W. , Lu, E. , Schwartzman, J. , Beja, K. , Annala, M. , Das, R. , Diolaiti, M. , Pritchard, C. , Thomas, G. , Tomlins, S. , Knudsen, K. , Lord, C. J. , Ryan, C. & 5 others Youngren, J., Beer, T. M., Ashworth, A., Small, E. J. & Feng, F. Y. Sep 1 2017 In : Cancer Discovery. 7, 9, p. 999-1005 7 p.

Research output: Contribution to journal › Article

Prostatic Neoplasms

Recombinational DNA Repair

Mutation

DNA Repair

Biopsy

9 Citations

Concordance of Circulating Tumor DNA and Matched Metastatic Tissue Biopsy in Prostate Cancer

Wyatt, A. W., Annala, M., Aggarwal, R., Beja, K., Feng, F., Youngren, J., Foye, A., Lloyd, P., Nykter, M., Beer, T. M., Alumkal, J. J., Thomas, G. V., Reiter, R. E., Rettig, M. B., Evans, C. P., Gao, A. C., Chi, K. N., Small, E. J. & Gleave, M. E. Dec 1 2017 In : Journal of the National Cancer Institute. 109, 12

Research output: Contribution to journal › Article

Castration-Resistant Prostatic Neoplasms

Retinoblastoma Binding Proteins

BRCA2 Protein

Adenomatous Polyposis Coli Protein

DNA Copy Number Variations

Double autophagy stimulation using chemotherapy and mTOR inhibition combined with hydroxychloroquine for autophagy modulation in patients with relapsed or refractory multiple myeloma

Scott, E. C., Maziarz, R. T., Spurgeon, S. E., Medvedova, E., Gajewski, J., Reasor-Heard, S., Park, B., Kratz, A., Thomas, G. V., Loriaux, M., Cascio, M., Podolak, J., Gordon, M., Botelho, J., Stadtmauer, E., Amaravadi, R. & Vogl, D. T. Jun 26 2017 In : Haematologica. 102, 7, p. e261-e265

Research output: Contribution to journal › Letter