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  • 14 Similar Profiles
Prostatic Neoplasms Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Prostate Medicine & Life Sciences
Renal Cell Carcinoma Medicine & Life Sciences
Mutation Medicine & Life Sciences
Stem Cells Medicine & Life Sciences
Castration Medicine & Life Sciences
tanespimycin Medicine & Life Sciences

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Projects 1997 2018

Inhibiting VHL-positive kidney cancer

Thomas, G.

National Institutes of Health


Project: Research projectResearch Project

Kidney Neoplasms
Renal Cell Carcinoma
STAT3 Transcription Factor


Mori, M. (., Corless, C., Beer, T. (., McWeeney, S., Harrington, C. (., Bagby, G., Druker, B., Sexton, G., Hall, A., Henner, W., Samuels, M. H., Bakke, A., Hoatlin, M., Baetscher, M., Keller, T., Nagalla, S., Magun, B. E., Koop, D. R., Mauro, M. J., Blanke, C. D., Bakke, A., Baetscher, M., Koop, D., Spellman, P., David, L., Coussens, L., Streeter, P., Thomas, G., Mori, M. (., Mori, M. (. & Harrington, C. (.

National Institutes of Health


Project: Research projectCenter Core Grants

Research Personnel
Translational Medical Research

Research Output 1998 2017

  • 6094 Citations
  • 30 h-Index
  • 55 Article
  • 1 Letter
10 Citations

Analysis of circulating cell-free DnA identifies multiclonal heterogeneity of BRCA2 reversion mutations associated with resistance to PARP inhibitors

Quigley, D. , Alumkal, J. J. , Wyatt, A. W. , Kothari, V. , Foye, A. , Lloyd, P. , Aggarwal, R. , Kim, W. , Lu, E. , Schwartzman, J. , Beja, K. , Annala, M. , Das, R. , Diolaiti, M. , Pritchard, C. , Thomas, G. , Tomlins, S. , Knudsen, K. , Lord, C. J. , Ryan, C. & 5 others Youngren, J., Beer, T. M., Ashworth, A., Small, E. J. & Feng, F. Y. Sep 1 2017 In : Cancer Discovery. 7, 9, p. 999-1005 7 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Recombinational DNA Repair
DNA Repair
6 Citations

Concordance of Circulating Tumor DNA and Matched Metastatic Tissue Biopsy in Prostate Cancer

Wyatt, A. W., Annala, M., Aggarwal, R., Beja, K., Feng, F., Youngren, J., Foye, A., Lloyd, P., Nykter, M., Beer, T. M., Alumkal, J. J., Thomas, G. V., Reiter, R. E., Rettig, M. B., Evans, C. P., Gao, A. C., Chi, K. N., Small, E. J. & Gleave, M. E. Dec 1 2017 In : Journal of the National Cancer Institute. 109, 12

Research output: Contribution to journalArticle

Castration-Resistant Prostatic Neoplasms
Retinoblastoma Binding Proteins
BRCA2 Protein
Adenomatous Polyposis Coli Protein
DNA Copy Number Variations

Double autophagy stimulation using chemotherapy and mTOR inhibition combined with hydroxychloroquine for autophagy modulation in patients with relapsed or refractory multiple myeloma

Scott, E. C., Maziarz, R. T., Spurgeon, S. E., Medvedova, E., Gajewski, J., Reasor-Heard, S., Park, B., Kratz, A., Thomas, G. V., Loriaux, M., Cascio, M., Podolak, J., Gordon, M., Botelho, J., Stadtmauer, E., Amaravadi, R. & Vogl, D. T. Jun 26 2017 In : Haematologica. 102, 7, p. e261-e265

Research output: Contribution to journalLetter

3 Citations

Impact of carbohydrate restriction in the context of obesity on prostate tumor growth in the Hi-Myc transgenic mouse model

Allott, E. H., Macias, E., Sanders, S., Knudsen, B. S., Thomas, G. V., Hursting, S. D. & Freedland, S. J. Jun 1 2017 In : Prostate Cancer and Prostatic Diseases. 20, 2, p. 165-171 7 p.

Research output: Contribution to journalArticle

Ketogenic Diet
Carbohydrate-Restricted Diet
Chemokine CCL2
Body Composition
Energy Intake

Metabolic reprogramming ensures cancer cell survival despite oncogenic signaling blockade

Lue, H. W. , Podolak, J. , Kolahi, K. , Cheng, L. , Rao, S. , Garg, D. , Xue, C. H. , Rantala, J. K. , Tyner, J. W. , Thornburg, K. L. , Martinez-Acevedo, A. , Liu, J. J. , Amling, C. L. , Truillet, C. , Louie, S. M. , Anderson, K. E. , Evans, M. J. , O’Donnell, V. B. , Nomura, D. K. , Drake, J. M. & 2 others Ritz, A. & Thomas, G. V. Oct 15 2017 In : Genes and Development. 31, 20, p. 2067-2084 18 p.

Research output: Contribution to journalArticle

Cell Survival
Phospholipases A2
Oxidative Phosphorylation