George Giraud

Professor

  • 3220 Citations
  • 27 h-Index
1977 …2019
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Research Output 1977 2019

  • 3220 Citations
  • 27 h-Index
  • 82 Article
  • 2 Chapter
  • 1 Conference contribution
  • 1 Review article
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Article
2019

Right ventricular remodeling in response to volume overload in fetal sheep

Karamlou, T., Giraud, G., McKeogh, D., Jonker, S., Shen, I., Ungerleider, R. M. & Thornburg, K., May 1 2019, In : American journal of physiology. Heart and circulatory physiology. 316, 5, p. H985-H991

Research output: Contribution to journalArticle

Ventricular Remodeling
Cardiac Myocytes
Sheep
Fetus
Heart Ventricles
1 Citation (Scopus)
Thyroid Hormone Receptors
Cardiac Myocytes
Sheep
Somatomedins
Bromodeoxyuridine
2018
3 Citations (Scopus)

Lipoprotein Apheresis Acutely Reverses Coronary Microvascular Dysfunction in Patients With Severe Hypercholesterolemia

Wu, M. D., Moccetti, F., Brown, E., Davidson, B. P., Atkinson, T. T., Belcik, J. T., Giraud, G., Duell, P., Fazio, S., Tavori, H., Tsimikas, S. & Lindner, J., Jan 1 2018, (Accepted/In press) In : JACC: Cardiovascular Imaging.

Research output: Contribution to journalArticle

Blood Component Removal
Hypercholesterolemia
Lipoproteins
Perfusion
Femoral Artery
Insulin-Like Growth Factor I
Cardiac Myocytes
Hypertension
Muscle Cells
Heart Ventricles
2017
13 Citations (Scopus)

Cardiovascular and Ventilatory Consequences of Laparoscopic Surgery

Atkinson, T. T., Giraud, G., Togioka, B., Jones, D. B. & Cigarroa, J., Feb 14 2017, In : Circulation. 135, 7, p. 700-710 11 p.

Research output: Contribution to journalArticle

Laparoscopy
Hemodynamics
Hypercapnia
Pressure
Lung Compliance
2016
2 Citations (Scopus)

Functional adaptations of the coronary microcirculation to anaemia in fetal sheep

Jonker, S., Davis, L., Soman, D., Belcik, J. T., Davidson, B. P., Atkinson, T. T., Wilburn, A., Louey, S., Giraud, G. & Lindner, J., Nov 1 2016, In : Journal of Physiology. 594, 21, p. 6165-6174 10 p.

Research output: Contribution to journalArticle

Microcirculation
Anemia
Sheep
Fetus
Hyperemia
2015
8 Citations (Scopus)

Effects of chronic hypoxia on cardiac function measured by pressure-volume catheter in fetal chickens

Jonker, S., Giraud, G., Espinoza, H. M., Davis, E. N. & Crossley, D. A., Apr 15 2015, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 308, 8, p. R680-R689

Research output: Contribution to journalArticle

Chickens
Catheters
Pressure
Heart Rate
Excitation Contraction Coupling
Heart Valves
Fetal Development
Aortic Valve
Mitral Valve
Sheep
1 Citation (Scopus)

Theophylline Pharmacokinetics in Foetal Sheep: Maternal Metabolic Capacity is the Principal Driver

Dubois, B., Louey, S., Giraud, G., Cherala, G. & Jonker, S., Oct 1 2015, In : Basic and Clinical Pharmacology and Toxicology. 117, 4, p. 226-233 8 p.

Research output: Contribution to journalArticle

Pharmacokinetics
Theophylline
Sheep
Mothers
Fetus
22 Citations (Scopus)

Timing of cardiomyocyte growth, maturation, and attrition in perinatal sheep

Jonker, S., Louey, S., Giraud, G., Thornburg, K. & Faber, J. J., Oct 1 2015, In : FASEB Journal. 29, 10, p. 4346-4357 12 p.

Research output: Contribution to journalArticle

Cardiac Myocytes
Sheep
Muscle Cells
Parturition
Growth
2014
13 Citations (Scopus)
Phosphatidylinositol 3-Kinases
Cardiac Myocytes
Somatomedins
Sheep
Phosphorylation
2013
18 Citations (Scopus)
Cardiac Arrhythmias
Obesity
Diet
High Fat Diet
Norepinephrine
2012
4 Citations (Scopus)

Left ventricular function and the systemic arterial vasculature: Remembering what we have learned

Davidson, B. P. & Giraud, G., Aug 2012, In : Journal of the American Society of Echocardiography. 25, 8, p. 891-894 4 p.

Research output: Contribution to journalArticle

Isometric Contraction
Left Ventricular Dysfunction
Left Ventricular Function
Carotid Arteries
Hypertension
16 Citations (Scopus)
Thyroid Hormones
Cardiac Myocytes
Sheep
Pregnancy
Thyronines
69 Citations (Scopus)

Thyroid hormone drives fetal cardiomyocyte maturation

Chattergoon, N., Giraud, G., Louey, S., Stork, P., Fowden, A. L. & Thornburg, K., Jan 2012, In : FASEB Journal. 26, 1, p. 397-408 12 p.

Research output: Contribution to journalArticle

Thyroid Hormones
Cardiac Myocytes
Cyclin D1
Cells
Thyronines
2011
3 Citations (Scopus)

Insignificant response of the fetal placental circulation to arterial hypotension in sheep

Faber, J. J., Anderson, D., Louey, S., Thornburg, K. & Giraud, G., Oct 2011, In : Journal of Applied Physiology. 111, 4, p. 1042-1047 6 p.

Research output: Contribution to journalArticle

Enalaprilat
Placental Circulation
Hypotension
Sheep
Arterial Pressure
54 Citations (Scopus)

Regulation of the cardiomyocyte population in the developing heart

Thornburg, K., Jonker, S., O'Tierney, P., Chattergoon, N., Louey, S., Faber, J. & Giraud, G., Jul 2011, In : Progress in Biophysics and Molecular Biology. 106, 1, p. 289-299 11 p.

Research output: Contribution to journalArticle

Cardiac Myocytes
Atrial Natriuretic Factor
Population
Angiotensin II
Cell Cycle
2010
27 Citations (Scopus)

Atrial natriuretic peptide inhibits angiotensin II-stimulated proliferation in fetal cardiomyocytes

O'Tierney, P. F., Chattergoon, N., Louey, S., Giraud, G. & Thornburg, K., Aug 2010, In : Journal of Physiology. 588, 15, p. 2879-2889 11 p.

Research output: Contribution to journalArticle

Atrial Natriuretic Factor
Cardiac Myocytes
Angiotensin II
MAP Kinase Kinase 3
Extracellular Signal-Regulated MAP Kinases
32 Citations (Scopus)

Cardiomyocyte enlargement, proliferation and maturation during chronic fetal anaemia in sheep

Jonker, S., Giraud, M. K., Giraud, G., Chattergoon, N., Louey, S., Davis, L., Faber, J. J. & Thornburg, K., Jan 2010, In : Experimental Physiology. 95, 1, p. 131-139 9 p.

Research output: Contribution to journalArticle

Cardiac Myocytes
Anemia
Sheep
Fetus
Tissue Expansion
33 Citations (Scopus)
Nerve Growth Factor Receptor
Adrenergic Receptors
Semaphorin-3A
Nerve Growth Factor
Neurons
19 Citations (Scopus)
Fetal Heart
Enalaprilat
Sheep
Cell Cycle
Fetus
2009
3 Citations (Scopus)

Greater nasal nitric oxide output during inhalation: Effects on air temperature and water content

Holden, W. E., Sippel, J. M., Nelson, B. & Giraud, G., Jan 1 2009, In : Respiratory Physiology and Neurobiology. 165, 1, p. 22-27 6 p.

Research output: Contribution to journalArticle

Nose
Inhalation
Nitric Oxide
Air
Temperature
2008
14 Citations (Scopus)

Effect of fetal anaemia on myocardial ischaemia-reperfusion injury and coronary vasoreactivity in adult sheep

Yang, Q., Hohimer, A. R., Giraud, G., Van Winkle, D. M., Underwood, M. J., He, G. W. & Davis, L., Dec 2008, In : Acta Physiologica. 194, 4, p. 325-334 10 p.

Research output: Contribution to journalArticle

Myocardial Reperfusion Injury
Reperfusion Injury
Myocardial Ischemia
Anemia
Sheep
4 Citations (Scopus)

Persistent changes in arterial blood gases in fetal sheep

Jonker, S., Anderson, D., Davis, L., Yang, Q., Faber, J. J. & Giraud, G., Jul 2008, In : Laboratory Animals. 42, 3, p. 326-330 5 p.

Research output: Contribution to journalArticle

blood gases
halothane
Halothane
diazepam
ewes
2007
6 Citations (Scopus)

Exhaled nasal nitric oxide output is reduced in humans at night during the sleep period

O'Hearn, D. J., Giraud, G., Sippel, J. M., Edwards, C., Chan, B. & Holden, W. E., Apr 15 2007, In : Respiratory Physiology and Neurobiology. 156, 1, p. 94-101 8 p.

Research output: Contribution to journalArticle

Nose
Sleep
Nitric Oxide
Ventilation
Nasal Mucosa
94 Citations (Scopus)

Myocyte enlargement, differentiation, and proliferation kinetics in the fetal sheep heart

Jonker, S., Zhang, L., Louey, S., Giraud, G., Thornburg, K. & Faber, J. J., Mar 2007, In : Journal of Applied Physiology. 102, 3, p. 1130-1142 13 p.

Research output: Contribution to journalArticle

Fetal Heart
Muscle Cells
Sheep
Cardiac Myocytes
Growth
76 Citations (Scopus)
Placental Insufficiency
Cardiac Myocytes
Sheep
Cell Cycle
Fetus
43 Citations (Scopus)
Fetal Development
Cardiac Myocytes
Muscle Cells
Sheep
Hypertension
34 Citations (Scopus)
Thyroid Hormones
Cardiac Myocytes
Bromodeoxyuridine
Pregnancy
Cell Cycle Proteins
2006
75 Citations (Scopus)

Cortisol stimulates cell cycle activity in the cardiomyocyte of the sheep fetus

Giraud, G., Louey, S., Jonker, S., Schultz, J. & Thornburg, K., 2006, In : Endocrinology. 147, 8, p. 3643-3649 7 p.

Research output: Contribution to journalArticle

Cardiac Myocytes
Hydrocortisone
Sheep
Cell Cycle
Fetus
6 Citations (Scopus)
Sheep
Arterial Pressure
Fetal Proteins
Umbilical Arteries
Venous Pressure
6 Citations (Scopus)

Fetal Infusions of Plasma Cause an Increase in Umbilical Vascular Resistance in Sheep

Faber, J. J., Anderson, D., Jonker, S., Davis, L. & Giraud, G., Aug 2006, In : Placenta. 27, 8, p. 876-881 6 p.

Research output: Contribution to journalArticle

Umbilicus
Placental Circulation
Vascular Resistance
Sheep
Pressure
2005
13 Citations (Scopus)

Function curve of the membranes that regulate amniotic fluid volume in sheep

Faber, J., Anderson, D., Hohimer, A. R., Yang, Q., Giraud, G. & Davis, L., Jul 2005, In : American Journal of Physiology - Heart and Circulatory Physiology. 289, 1 58-1

Research output: Contribution to journalArticle

Amniotic Fluid
Sheep
Membranes
Urine
Amnion
15 Citations (Scopus)

Intramembranous absorption rate is unaffected by changes in amniotic fluid composition

Anderson, D., Yang, Q., Hohimer, A. R., Faber, J., Giraud, G. & Davis, L., May 2005, In : American Journal of Physiology - Renal Physiology. 288, 5 57-5

Research output: Contribution to journalArticle

Amniotic Fluid
Urachus
Fetus
Urine
Ligation
12 Citations (Scopus)

Intravascular infusions of plasma into fetal sheep cause arterial and venous hypertension

Giraud, G., Faber, J. J., Jonker, S., Davis, L. & Anderson, D., Sep 2005, In : Journal of Applied Physiology. 99, 3, p. 884-889 6 p.

Research output: Contribution to journalArticle

Sheep
Fetus
Hypertension
Fetal Proteins
Venous Pressure
34 Citations (Scopus)

The effects of anaemia as a programming agent in the fetal heart

Davis, L., Thornburg, K. & Giraud, G., May 15 2005, In : Journal of Physiology. 565, 1, p. 35-41 7 p.

Research output: Contribution to journalArticle

Fetal Heart
Anemia
Cardiovascular System
Viscosity
Glucocorticoids
2004
30 Citations (Scopus)

Electrophysiologic predictors of the recurrence of persistent atrial fibrillation within 30 days of cardioversion

Raitt, M. H., Kusumoto, W., Giraud, G. & McAnulty, J. H., Jan 1 2004, In : American Journal of Cardiology. 93, 1, p. 107-110 4 p.

Research output: Contribution to journalArticle

Atrial Premature Complexes
Electric Countershock
Atrial Fibrillation
Recurrence
63 Citations (Scopus)

Reversal of electrical remodeling after cardioversion of persistent atrial fibrillation

Raitt, M. H., Kusumoto, W., Giraud, G. & Mcanulty, J. H., May 2004, In : Journal of Cardiovascular Electrophysiology. 15, 5, p. 507-512 6 p.

Research output: Contribution to journalArticle

Atrial Remodeling
Electric Countershock
Atrial Fibrillation
Sinoatrial Node
Coronary Sinus
2003
18 Citations (Scopus)

Anaemia stimulates aquaporin 1 expression in the fetal sheep heart

Jonker, S., Davis, L., van der Bilt, J. D. W., Hadder, B., Hohimer, A. R., Giraud, G. & Thornburg, K., Nov 2003, In : Experimental Physiology. 88, 6, p. 691-698 8 p.

Research output: Contribution to journalArticle

Aquaporin 1
Fetal Heart
Anemia
Sheep
Fetus
74 Citations (Scopus)

Angiotensin II stimulates hyperplasia but not hypertrophy in immature ovine cardiomyocytes

Sundgren, N. C., Giraud, G., Stork, P., Maylie, J. & Thornburg, K., May 1 2003, In : Journal of Physiology. 548, 3, p. 881-891 11 p.

Research output: Contribution to journalArticle

Cardiac Myocytes
Angiotensin II
Hypertrophy
Hyperplasia
Sheep
88 Citations (Scopus)
Mitogen-Activated Protein Kinase 6
Somatomedins
Cardiac Myocytes
Sheep
Phosphotransferases
31 Citations (Scopus)
Anemia
Left Ventricular Function
Sheep
Phlebotomy
Ventricular Pressure
10 Citations (Scopus)

Pregnancy alters hemodynamic responses to hemorrhage in conscious rabbits

Clow, K. A., Giraud, G., Ogden, B. E. & Brooks, V., Apr 1 2003, In : American Journal of Physiology - Heart and Circulatory Physiology. 284, 4 53-4

Research output: Contribution to journalArticle

Cardiac Output
Hemodynamics
Hemorrhage
Rabbits
Arterial Pressure
2002
16 Citations (Scopus)
Adenosine
Sheep
Coronary Vessels
Fetus
Growth
2001
11 Citations (Scopus)
Vasodilation
Nitric Oxide
Rabbits
Pregnancy
Blood Vessels
7 Citations (Scopus)

Hemodynamic effects of S-nitrosocysteine, an intravenous regional vasodilator

Stuesse, D. C., Giraud, G., Vlessis, A., Starr, A., Trunkey, D., Verrier, E. & Fullerton, D., Aug 1 2001, In : Journal of Thoracic and Cardiovascular Surgery. 122, 2, p. 371-377 7 p.

Research output: Contribution to journalArticle

Vasodilator Agents
Hemodynamics
Lung
Cardiac Output
Pressure
2000
156 Citations (Scopus)

Hemodynamic changes in pregnancy

Thornburg, K., Jacobson, S. L., Giraud, G. & Morton, M. J., 2000, In : Seminars in Perinatology. 24, 1, p. 11-14 4 p.

Research output: Contribution to journalArticle

Hemodynamics
Pregnancy
Blood Volume
Stroke Volume
Pregnant Women
96 Citations (Scopus)
Ventricular Pressure
Muscle Cells
Sheep
Blood Pressure
Pulmonary Artery
1999
32 Citations (Scopus)

Accuracy of Doppler methods for estimating peak-to-peak and peak instantaneous gradients across coarctation of the aorta: An in vitro study

Seifert, B. L., DesRochers, K., Ta, M., Giraud, G., Zarandi, M., Gharib, M. & Sahn, D., 1999, In : Journal of the American Society of Echocardiography. 12, 9, p. 744-753 10 p.

Research output: Contribution to journalArticle

Aortic Coarctation
Thoracic Aorta
Pressure
Catheters
Aorta
26 Citations (Scopus)

Angiotensin type 1 receptor antagonism with irbesartan inhibits ventricular hypertrophy and improves diastolic function in the remodeling post-myocardial infarction ventricle

Ambrose, J., Pribnow, D. G., Giraud, G., Perkins, K. D., Muldoon, L. & Greenberg, B. H., Mar 1999, In : Journal of Cardiovascular Pharmacology. 33, 3, p. 433-439 7 p.

Research output: Contribution to journalArticle

irbesartan
Angiotensin Type 1 Receptor
Hypertrophy
Myocardial Infarction
Atrial Natriuretic Factor