Ayna Alfadhli

Research Assistant Professor

  • 536 Citations
  • 12 h-Index
20012019
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Research Output 2001 2019

  • 536 Citations
  • 12 h-Index
  • 18 Article
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Article
2019

Organization of Farnesylated, Carboxymethylated KRAS4B on Membranes

Barklis, E., Stephen, A. G., Staubus, A. O., Barklis, R. L. & Alfadhli, A., Jan 1 2019, In : Journal of molecular biology.

Research output: Contribution to journalArticle

Membranes
Proteins
Prenylation
ras Proteins
Post Translational Protein Processing
2018

Lipid biosensor interactions with wild type and matrix deletion HIV-1 Gag proteins

Barklis, E., Staubus, A. O., Mack, A., Harper, L., Barklis, R. L. & Alfadhli, A., May 1 2018, In : Virology. 518, p. 264-271 8 p.

Research output: Contribution to journalArticle

gag Gene Products
Biosensing Techniques
HIV-1
Lipids
Viral Proteins
2017
1 Citation (Scopus)

Analysis of K-Ras interactions by biotin ligase tagging

Ritchie, C., Mack, A., Harper, L., Alfadhli, A., Stork, P., Nan, X. & Barklis, E., Jul 1 2017, In : Cancer Genomics and Proteomics. 14, 4, p. 225-239 15 p.

Research output: Contribution to journalArticle

Ligases
Biotin
ras Proteins
Cells
Prenylation
2016
4 Citations (Scopus)

Analysis of quinolinequinone reactivity, cytotoxicity, and anti-HIV-1 properties

Alfadhli, A., Mack, A., Harper, L., Berk, S., Ritchie, C. & Barklis, E., Nov 1 2016, In : Bioorganic and Medicinal Chemistry. 24, 21, p. 5618-5625 8 p.

Research output: Contribution to journalArticle

Cytotoxicity
HIV-1
Viruses
Proteins
Crosslinking
4 Citations (Scopus)

Trimer enhancement mutation effects on HIV-1 matrix protein binding activities

Alfadhli, A., Mack, A., Ritchie, C., Cylinder, I., Harper, L., Tedbury, P. R., Freed, E. O. & Barklis, E., Jun 1 2016, In : Journal of Virology. 90, 12, p. 5657-5664 8 p.

Research output: Contribution to journalArticle

protein binding
Human immunodeficiency virus 1
Protein Binding
HIV-1
mutation
2014
16 Citations (Scopus)

The roles of lipids and nucleic acids in HIV-1 assembly

Alfadhli, A. & Barklis, E., 2014, In : Frontiers in Microbiology. 5, MAY

Research output: Contribution to journalArticle

gag Gene Products
Nucleic Acids
HIV-1
Lipids
Nucleocapsid
2013
13 Citations (Scopus)

Analysis of small molecule ligands targeting the HIV-1 matrix protein-RNA binding site

Alfadhli, A., McNett, H., Eccles, J., Tsagli, S., Noviello, C., Sloan, R., Lopez, C., Peyton, D. H. & Barklis, E., Jan 4 2013, In : Journal of Biological Chemistry. 288, 1, p. 666-676 11 p.

Research output: Contribution to journalArticle

RNA
HIV-1
Binding Sites
Ligands
Proteins
2011
49 Citations (Scopus)

HIV-1 matrix protein binding to RNA

Alfadhli, A., McNett, H., Tsagli, S., Bächinger, H. P., Peyton, D. H. & Barklis, E., Jul 22 2011, In : Journal of Molecular Biology. 410, 4, p. 653-666 14 p.

Research output: Contribution to journalArticle

RNA-Binding Proteins
HIV-1
RNA
gag Gene Products
HIV
2009
89 Citations (Scopus)

Analysis of human immunodeficiency virus type 1 matrix binding to membranes and nucleic acids

Alfadhli, A., Still, A. & Barklis, E., Dec 2009, In : Journal of Virology. 83, 23, p. 12196-12203 8 p.

Research output: Contribution to journalArticle

Human immunodeficiency virus 1
Nucleic Acids
nucleic acids
HIV-1
Liposomes
35 Citations (Scopus)

Characterization of the In Vitro HIV-1 Capsid Assembly Pathway

Barklis, E., Alfadhli, A., McQuaw, C., Yalamuri, S., Still, A., Barklis, R. L., Kukull, B. & Lopez, C., Mar 27 2009, In : Journal of Molecular Biology. 387, 2, p. 376-389 14 p.

Research output: Contribution to journalArticle

Capsid
HIV-1
Capsid Proteins
Antiviral Agents
Virus Uncoating
58 Citations (Scopus)

HIV-1 matrix organizes as a hexamer of trimers on membranes containing phosphatidylinositol-(4,5)-bisphosphate

Alfadhli, A., Barklis, R. L. & Barklis, E., May 10 2009, In : Virology. 387, 2, p. 466-472 7 p.

Research output: Contribution to journalArticle

gag Gene Products
Phosphatidylinositols
Myristic Acid
HIV-1
Membranes
2007
32 Citations (Scopus)

Human immunodeficiency virus type 1 matrix protein assembles on membranes as a hexamer

Alfadhli, A., Huseby, D., Kapit, E., Colman, D. & Barklis, E., Feb 2007, In : Journal of Virology. 81, 3, p. 1472-1478 7 p.

Research output: Contribution to journalArticle

Human immunodeficiency virus 1
HIV-1
Membranes
Capsid Proteins
coat proteins
10 Citations (Scopus)

Sultam thiourea inhibition of West Nile virus

Barklis, E., Still, A., Sabri, M. I., Hirsch, A., Nikolich-Zugich, J., Brien, J., Dhenub, T. C., Scholz, I. & Alfadhli, A., Jul 2007, In : Antimicrobial Agents and Chemotherapy. 51, 7, p. 2642-2645 4 p.

Research output: Contribution to journalArticle

West Nile virus
Thiourea
Virus Replication
Replicon
naphthosultone
2005
34 Citations (Scopus)

Analysis of human immunodeficiency virus type 1 Gag dimerization-induced assembly

Alfadhli, A., Dhenub, T. C., Still, A. & Barklis, E., Dec 2005, In : Journal of Virology. 79, 23, p. 14498-14506 9 p.

Research output: Contribution to journalArticle

gag Gene Products
Nucleocapsid
dimerization
Dimerization
Human immunodeficiency virus 1
42 Citations (Scopus)

Assembly of human immunodeficiency virus precursor gag proteins

Huseby, D., Barklis, R. L., Alfadhli, A. & Barklist, E., May 6 2005, In : Journal of Biological Chemistry. 280, 18, p. 17664-17670 7 p.

Research output: Contribution to journalArticle

Human Immunodeficiency Virus gag Gene Products
gag Gene Products
Viruses
Capsid
Virion
2002
57 Citations (Scopus)

Hantavirus nucleocapsid protein coiled-coil domains

Alfadhli, A., Steel, E., Finlay, L., Bächinger, H. P. & Barklis, E., Jul 26 2002, In : Journal of Biological Chemistry. 277, 30, p. 27103-27108 6 p.

Research output: Contribution to journalArticle

Hantavirus
Nucleocapsid Proteins
Sin Nombre virus
Viruses
Peptides
2001
22 Citations (Scopus)

Effects of Diabetes Insipidus Mutations on Neurophysin Folding and Function

Eubanks, S., Nguyen, T. L., Deeb, R., Villafania, A., Alfadhli, A. & Breslow, E., Aug 10 2001, In : Journal of Biological Chemistry. 276, 32, p. 29671-29680 10 p.

Research output: Contribution to journalArticle

Neurophysins
Diabetes Insipidus
Medical problems
Vasopressins
Thermodynamics
70 Citations (Scopus)

Hantavirus nucleocapsid protein oligomerization

Alfadhli, A., Love, Z., Arvidson, B., Seeds, J., Willey, J. & Barklis, E., 2001, In : Journal of Virology. 75, 4, p. 2019-2023 5 p.

Research output: Contribution to journalArticle

Hantavirus
nucleocapsid proteins
Nucleocapsid Proteins
Proteins
proteins