Aaron Nilsen

Senior Staff Scientist

  • 645 Citations
  • 15 h-Index
20042019
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Research Output 2004 2019

  • 645 Citations
  • 15 h-Index
  • 30 Article

ELQ-331 as a prototype for extremely durable chemoprotection against malaria

Smilkstein, M. J., Pou, S., Krollenbrock, A., Bleyle, L. A., Dodean, R. A., Frueh, L., Hinrichs, D. J., Li, Y., Martinson, T., Munar, M. Y., Winter, R. W., Bruzual, I., Whiteside, S., Nilsen, A., Koop, D., Kelly, J. X., Kappe, S. H. I., Wilder, B. K. & Riscoe, M., Aug 27 2019, In : Malaria Journal. 18, 1, 291.

Research output: Contribution to journalArticle

Open Access
Malaria
Prodrugs
Plasmodium yoelii
Pharmacokinetics
Sporozoites
3 Citations (Scopus)

Mitochondrial type II NADH dehydrogenase of Plasmodium falciparum (PfNDH2) is dispensable in the asexual blood stages

Ke, H., Ganesan, S. M., Dass, S., Morrisey, J. M., Pou, S., Nilsen, A., Riscoe, M., Mather, M. W. & Vaidya, A. B., Apr 1 2019, In : PloS one. 14, 4, e0214023.

Research output: Contribution to journalArticle

Open Access
NADH dehydrogenase
Plasmodium falciparum
Parasites
antimalarials
Blood

Targeting mitochondria in cancer therapy could provide a basis for the selective anticancer activity

Rozanov, D., Cheltsov, A., Nilsen, A., Boniface, C., Forquer, I., Korkola, J., Gray, J., Tyner, J., Tognon, C. E., Mills, G. & Spellman, P., Mar 1 2019, In : PloS one. 14, 3, e0205623.

Research output: Contribution to journalArticle

Open Access
Mitochondria
Assays
mitochondria
therapeutics
neoplasms
2 Citations (Scopus)

Characterization and structure-activity relationship analysis of a class of antiviral compounds that directly bind dengue virus capsid protein and are incorporated into virions

Smith, J. L., Sheridan, K., Parkins, C. J., Frueh, L., Jemison, A. L., Strode, K., Dow, G., Nilsen, A. & Hirsch, A., Jul 1 2018, In : Antiviral Research. 155, p. 12-19 8 p.

Research output: Contribution to journalArticle

Dengue Virus
Capsid Proteins
Structure-Activity Relationship
Virion
Antiviral Agents
3 Citations (Scopus)

Emerging alphaviruses are sensitive to cellular states induced by a novel small-molecule agonist of the STING pathway

Gall, B., Pryke, K., Abraham, J., Mizuno, N., Botto, S., Sali, T. M., Broeckel, R., Haese, N., Nilsen, A., Placzek, A., Morrison, T., Heise, M., Streblow, D. & De Filippis, V., Mar 1 2018, In : Journal of Virology. 92, 6, e01913-17.

Research output: Contribution to journalArticle

Alphavirus
interferons
Interferons
agonists
Interferon Type I