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17q21.31 Microdeletion associated with infantile spasms

Wray, C. D., Jan 1 2013, In : European Journal of Medical Genetics. 56, 1, p. 59-61 3 p.

Research output: Contribution to journalArticle

9 Scopus citations

Activation of β-catenin/TCF targets following loss of the tumor suppressor SNF5

Mora-Blanco, E. L., Mishina, Y., Tillman, E. J., Cho, Y. J., Thom, C. S., Pomeroy, S. L., Shao, W. & Roberts, C. W. M., Feb 13 2014, In : Oncogene. 33, 7, p. 933-938 6 p.

Research output: Contribution to journalArticle

37 Scopus citations

A first-in-class twist1 inhibitor with activity in oncogene-driven lung cancer

Yochum, Z. A., Cades, J., Mazzacurati, L., Neumann, N. M., Khetarpal, S. K., Chatterjee, S., Wang, H., Attar, M. A., Huang, E. H. B., Chatley, S. N., Nugent, K., Somasundaram, A., Engh, J. A., Ewald, A. J., Cho, Y. J., Rudin, C. M., Tran, P. T. & Burns, T. F., Dec 2017, In : Molecular Cancer Research. 15, 12, p. 1764-1776 13 p.

Research output: Contribution to journalArticle

Open Access
15 Scopus citations

An Animal Model of MYC-Driven Medulloblastoma

Pei, Y., Moore, C. E., Wang, J., Tewari, A. K., Eroshkin, A., Cho, Y. J., Witt, H., Korshunov, A., Read, T. A., Sun, J. L., Schmitt, E. M., Miller, C. R., Buckley, A. F., McLendon, R. E., Westbrook, T. F., Northcott, P. A., Taylor, M. D., Pfister, S. M., Febbo, P. G. & Wechsler-Reya, R. J., Feb 14 2012, In : Cancer Cell. 21, 2, p. 155-167 13 p.

Research output: Contribution to journalArticle

Open Access
178 Scopus citations

A new mutation in MT-ND1 m.3928G>C p.V208L causes Leigh disease with infantile spasms

Wray, C. D., Friederich, M. W., du Sart, D., Pantaleo, S., Smet, J., Kucera, C., Fenton, L., Scharer, G., Van Coster, R. & Van Hove, J. L. K., Nov 1 2013, In : Mitochondrion. 13, 6, p. 656-661 6 p.

Research output: Contribution to journalArticle

11 Scopus citations

An injectable, biodegradable hydrogel for trophic factor delivery enhances axonal rewiring and improves performance after spinal cord injury

Piantino, J., Burdick, J. A., Goldberg, D., Langer, R. & Benowitz, L. I., Oct 1 2006, In : Experimental Neurology. 201, 2, p. 359-367 9 p.

Research output: Contribution to journalArticle

151 Scopus citations

Arhgap36-dependent activation of Gli transcription factors

Rack, P. G., Ni, J., Payumo, A. Y., Nguyen, V., Crapster, J. A., Hovestadt, V., Kool, M., Jones, D. T. W., Mich, J. K., Firestone, A. J., Pfister, S. M., Cho, Y. J. & Chen, J. K., Jan 1 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 30, p. 11061-11066 6 p.

Research output: Contribution to journalArticle

Open Access
17 Scopus citations

A treatable metabolic cause of encephalopathy: Cobalamin C deficiency in an 8-year-old male

Krueger, J. M., Piantino, J., Smith, C. M., Angle, B., Venkatesan, C. & Wainwright, M. S., Jan 1 2015, In : Pediatrics. 135, 1, p. e202-e206

Research output: Contribution to journalArticle

2 Scopus citations

BAF complexes facilitate decatenation of DNA by topoisomerase IIα

Dykhuizen, E. C., Hargreaves, D. C., Miller, E. L., Cui, K., Korshunov, A., Kool, M., Pfister, S., Cho, Y. J., Zhao, K. & Crabtree, G. R., May 30 2013, In : Nature. 497, 7451, p. 624-627 4 p.

Research output: Contribution to journalArticle

138 Scopus citations

BET bromodomain inhibition of MYC-amplified medulloblastoma

Bandopadhayay, P., Bergthold, G., Nguyen, B., Schubert, S., Gholamin, S., Tang, Y., Bolin, S., Schumacher, S. E., Zeid, R., Masoud, S., Yu, F., Vue, N., Gibson, W. J., Paolella, B. R., Mitra, S. S., Cheshier, S. H., Qi, J., Liu, K. W., Wechsler-Reya, R., Weiss, W. A. & 5 others, Swartling, F. J., Kieran, M. W., Bradner, J. E., Beroukhim, R. & Cho, Y. J., Jan 1 2014, In : Clinical Cancer Research. 20, 4, p. 912-925 14 p.

Research output: Contribution to journalArticle

Open Access
168 Scopus citations

Biological and clinical heterogeneity of MYCN-amplified medulloblastoma

Korshunov, A., Remke, M., Kool, M., Hielscher, T., Northcott, P. A., Williamson, D., Pfaff, E., Witt, H., Jones, D. T. W., Ryzhova, M., Cho, Y. J., Wittmann, A., Benner, A., Weiss, W. A., Von Deimling, A., Scheurlen, W., Kulozik, A. E., Clifford, S. C., Collins, V. P., Westermann, F. & 3 others, Taylor, M. D., Lichter, P. & Pfister, S. M., Apr 1 2012, In : Acta Neuropathologica. 123, 4, p. 515-527 13 p.

Research output: Contribution to journalArticle

49 Scopus citations

Cannabis Use in Children With Pantothenate Kinase–Associated Neurodegeneration

Wilson, J. L., Gregory, A., Wakeman, K., Freed, A., Rai, P., Roberts, C., Hayflick, S. J. & Hogarth, P., Mar 1 2020, In : Journal of child neurology. 35, 4, p. 259-264 6 p.

Research output: Contribution to journalArticle

Casein kinase 2 inhibition sensitizes medulloblastoma to temozolomide

Nitta, R. T., Bolin, S., Luo, E., Solow-Codero, D. E., Samghabadi, P., Purzner, T., Aujla, P. S., Nwagbo, G., Cho, Y-J. & Li, G., Jan 1 2019, (Accepted/In press) In : Oncogene.

Research output: Contribution to journalArticle

Open Access

Cerebral blood flow heterogeneity in preterm sheep: Lack of physiologic support for vascular boundary zones in fetal cerebral white matter

McClure, M. M., Riddle, A., Manese, M., Luo, N. L., Rorvik, D. A., Kelly, K. A., Barlow, C. H., Kelly, J. J., Vinecore, K., Roberts, C. T., Hohimer, A. R. & Back, S. A., May 1 2008, In : Journal of Cerebral Blood Flow and Metabolism. 28, 5, p. 995-1008 14 p.

Research output: Contribution to journalArticle

50 Scopus citations

Chondrocyte differentiation in a rat mesenchymal cell line

Lunstrum, G. P., Keene, D. R., Weksler, N. B., Cho, Y. J., Cornwall, M. & Horton, W. A., Jan 1999, In : Journal of Histochemistry and Cytochemistry. 47, 1, p. 1-6 6 p.

Research output: Contribution to journalArticle

57 Scopus citations

Clonal selection drives genetic divergence of metastatic medulloblastoma

Wu, X., Northcott, P. A., Dubuc, A., Dupuy, A. J., Shih, D. J. H., Witt, H., Croul, S., Bouffet, E., Fults, D. W., Eberhart, C. G., Garzia, L., Van Meter, T., Zagzag, D., Jabado, N., Schwartzentruber, J., Majewski, J., Scheetz, T. E., Pfister, S. M., Korshunov, A., Li, X. N. & 12 others, Scherer, S. W., Cho, Y. J., Akagi, K., MacDonald, T. J., Koster, J., McCabe, M. G., Sarver, A. L., Collins, V. P., Weiss, W. A., Largaespada, D. A., Collier, L. S. & Taylor, M. D., Feb 23 2012, In : Nature. 482, 7386, p. 529-533 5 p.

Research output: Contribution to journalArticle

292 Scopus citations

Combined BET bromodomain and CDK2 inhibition in MYC-driven medulloblastoma

Bolin, S., Borgenvik, A., Persson, C. U., Sundström, A., Qi, J., Bradner, J. E., Weiss, W. A., Cho, Y-J., Weishaupt, H. & Swartling, F. J., May 1 2018, In : Oncogene. 37, 21, p. 2850-2862 13 p.

Research output: Contribution to journalArticle

Open Access
12 Scopus citations

Cytogenetic prognostication within medulloblastoma subgroups

Shih, D. J. H., Northcott, P. A., Remke, M., Korshunov, A., Ramaswamy, V., Kool, M., Luu, B., Yao, Y., Wang, X., Dubuc, A. M., Garzia, L., Peacock, J., Mack, S. C., Wu, X., Rolider, A., Morrissy, A. S., Cavalli, F. M. G., Jones, D. T. W., Zitterbart, K., Faria, C. C. & 73 others, Schüller, U., Kren, L., Kumabe, T., Tominaga, T., Ra, Y. S., Garami, M., Hauser, P., Chan, J. A., Robinson, S., Bognár, L., Klekner, A., Saad, A. G., Liau, L. M., Albrecht, S., Fontebasso, A., Cinalli, G., De Antonellis, P., Zollo, M., Cooper, M. K., Thompson, R. C., Bailey, S., Lindsey, J. C., Di Rocco, C., Massimi, L., Michiels, E. M. C., Scherer, S. W., Phillips, J. J., Gupta, N., Fan, X., Muraszko, K. M., Vibhakar, R., Eberhart, C. G., Fouladi, M., Lach, B., Jung, S., Wechsler-Reya, R. J., Fèvre-Montange, M., Jouvet, A., Jabado, N., Pollack, I. F., Weiss, W. A., Lee, J. Y., Cho, B. K., Kim, S. K., Wang, K. C., Leonard, J. R., Rubin, J. B., De Torres, C., Lavarino, C., Mora, J., Cho, Y. J., Tabori, U., Olson, J. M., Gajjar, A., Packer, R. J., Rutkowski, S., Pomeroy, S. L., French, P. J., Kloosterhof, N. K., Kros, J. M., Van Meir, E. G., Clifford, S. C., Bourdeaut, F., Delattre, O., Doz, F. F., Hawkins, C. E., Malkin, D., Grajkowska, W. A., Perek-Polnik, M., Bouffet, E., Rutka, J. T., Pfister, S. M. & Taylor, M. D., Mar 20 2014, In : Journal of Clinical Oncology. 32, 9, p. 886-896 11 p.

Research output: Contribution to journalArticle

146 Scopus citations

Dasatinib suppression of medulloblastoma survival and migration is markedly enhanced by combining treatment with the aurora kinase inhibitor AT9283

Petersen, W., Liu, J., Yuan, L., Zhang, H., Schneiderjan, M., Cho, Y. J. & MacDonald, T. J., Nov 1 2014, In : Cancer Letters. 354, 1, p. 68-76 9 p.

Research output: Contribution to journalArticle

10 Scopus citations

Delineation of Two Clinically and Molecularly Distinct Subgroups of Posterior Fossa Ependymoma

Witt, H., Mack, S. C., Ryzhova, M., Bender, S., Sill, M., Isserlin, R., Benner, A., Hielscher, T., Milde, T., Remke, M., Jones, D. T. W., Northcott, P. A., Garzia, L., Bertrand, K. C., Wittmann, A., Yao, Y., Roberts, S. S., Massimi, L., Van Meter, T., Weiss, W. A. & 16 others, Gupta, N., Grajkowska, W., Lach, B., Cho, Y. J., von Deimling, A., Kulozik, A. E., Witt, O., Bader, G. D., Hawkins, C. E., Tabori, U., Guha, A., Rutka, J. T., Lichter, P., Korshunov, A., Taylor, M. D. & Pfister, S. M., Aug 16 2011, In : Cancer Cell. 20, 2, p. 143-157 15 p.

Research output: Contribution to journalArticle

Open Access
281 Scopus citations

Developmental phosphoproteomics identifies the kinase CK2 as a driver of Hedgehog signaling and a therapeutic target in medulloblastoma

Purzner, T., Purzner, J., Buckstaff, T., Cozza, G., Gholamin, S., Rusert, J. M., Hartl, T. A., Sanders, J., Conley, N., Ge, X., Langan, M., Ramaswamy, V., Ellis, L., Litzenburger, U., Bolin, S., Theruvath, J., Nitta, R., Qi, L., Li, X. N., Li, G. & 7 others, Taylor, M. D., Wechsler-Reya, R. J., Pinna, L. A., Cho, Y. J., Fuller, M. T., Elias, J. E. & Scott, M. P., Sep 11 2018, In : Science signaling. 11, 547, eaau5147.

Research output: Contribution to journalArticle

9 Scopus citations

Diffusion-weighted MRI derived apparent diffusion coefficient identifies prognostically distinct subgroups of pediatric diffuse intrinsic pontine glioma

Lober, R. M., Cho, Y. J., Tang, Y., Barnes, P. D., Edwards, M. S., Vogel, H., Fisher, P. G., Monje, M. & Yeom, K. W., Jan 1 2014, In : Journal of Neuro-Oncology. 117, 1, p. 175-182 8 p.

Research output: Contribution to journalArticle

35 Scopus citations

Disrupting the CD47-SIRPα anti-phagocytic axis by a humanized anti-CD47 antibody is an efficacious treatment for malignant pediatric brain tumors

Gholamin, S., Mitra, S. S., Feroze, A. H., Liu, J., Kahn, S. A., Zhang, M., Esparza, R., Richard, C., Ramaswamy, V., Remke, M., Volkmer, A. K., Willingham, S., Ponnuswami, A., McCarty, A., Lovelace, P., Storm, T. A., Schubert, S., Hutter, G., Narayanan, C., Chu, P. & 14 others, Raabe, E. H., Harsh, G., Taylor, M. D., Monje, M., Cho, Y-J., Majeti, R., Volkmer, J. P., Fisher, P. G., Grant, G., Steinberg, G. K., Vogel, H., Edwards, M., Weissman, I. L. & Cheshier, S. H., Mar 15 2017, In : Science Translational Medicine. 9, 381, eaaf2968.

Research output: Contribution to journalArticle

85 Scopus citations

Dissecting the genomic complexity underlying medulloblastoma

Jones, D. T. W., Jäger, N., Kool, M., Zichner, T., Hutter, B., Sultan, M., Cho, Y. J., Pugh, T. J., Hovestadt, V., Stütz, A. M., Rausch, T., Warnatz, H. J., Ryzhova, M., Bender, S., Sturm, D., Pleier, S., Cin, H., Pfaff, E., Sieber, L., Wittmann, A. & 70 others, Remke, M., Witt, H., Hutter, S., Tzaridis, T., Weischenfeldt, J., Raeder, B., Avci, M., Amstislavskiy, V., Zapatka, M., Weber, U. D., Wang, Q., Lasitschka, B., Bartholomae, C. C., Schmidt, M., von Kalle, C., Ast, V., Lawerenz, C., Eils, J., Kabbe, R., Benes, V., van Sluis, P., Koster, J., Volckmann, R., Shih, D., Betts, M. J., Russell, R. B., Coco, S., Tonini, G. P., Schüller, U., Hans, V., Graf, N., Kim, Y. J., Monoranu, C., Roggendorf, W., Unterberg, A., Herold-Mende, C., Milde, T., Kulozik, A. E., von Deimling, A., Witt, O., Maass, E., Rössler, J., Ebinger, M., Schuhmann, M. U., Frühwald, M. C., Hasselblatt, M., Jabado, N., Rutkowski, S., von Bueren, A. O., Williamson, D., Clifford, S. C., Mc Cabe, M. G., Collins, V. P., Wolf, S., Wiemann, S., Lehrach, H., Brors, B., Scheurlen, W., Felsberg, J., Reifenberger, G., Northcott, P. A., Taylor, M. D., Meyerson, M., Pomeroy, S. L., Yaspo, M. L., Korbel, J. O., Korshunov, A., Eils, R., Pfister, S. M. & Lichter, P., Aug 2 2012, In : Nature. 488, 7409, p. 100-105 6 p.

Research output: Contribution to journalArticle

Open Access
515 Scopus citations

Divergent clonal selection dominates medulloblastoma at recurrence

Morrissy, A. S., Garzia, L., Shih, D. J. H., Zuyderduyn, S., Huang, X., Skowron, P., Remke, M., Cavalli, F. M. G., Ramaswamy, V., Lindsay, P. E., Jelveh, S., Donovan, L. K., Wang, X., Luu, B., Zayne, K., Li, Y., Mayoh, C., Thiessen, N., Mercier, E., Mungall, K. L. & 118 others, Ma, Y., Tse, K., Zeng, T., Shumansky, K., Roth, A. J. L., Shah, S., Farooq, H., Kijima, N., Holgado, B. L., Lee, J. J. Y., Matan-Lithwick, S., Liu, J., Mack, S. C., Manno, A., Michealraj, K. A., Nor, C., Peacock, J., Qin, L., Reimand, J., Rolider, A., Thompson, Y. Y., Wu, X., Pugh, T., Ally, A., Bilenky, M., Butterfield, Y. S. N., Carlsen, R., Cheng, Y., Chuah, E., Corbett, R. D., Dhalla, N., He, A., Lee, D., Li, H. I., Long, W., Mayo, M., Plettner, P., Qian, J. Q., Schein, J. E., Tam, A., Wong, T., Birol, I., Zhao, Y., Faria, C. C., Pimentel, J., Nunes, S., Shalaby, T., Grotzer, M., Pollack, I. F., Hamilton, R. L., Li, X. N., Bendel, A. E., Fults, D. W., Walter, A. W., Kumabe, T., Tominaga, T., Collins, V. P., Cho, Y. J., Hoffman, C., Lyden, D., Wisoff, J. H., Garvin, J. H., Stearns, D. S., Massimi, L., Schüller, U., Sterba, J., Zitterbart, K., Puget, S., Ayrault, O., Dunn, S. E., Tirapelli, D. P. C., Carlotti, C. G., Wheeler, H., Hallahan, A. R., Ingram, W., MacDonald, T. J., Olson, J. J., Van Meir, E. G., Lee, J. Y., Wang, K. C., Kim, S. K., Cho, B. K., Pietsch, T., Fleischhack, G., Tippelt, S., Ra, Y. S., Bailey, S., Lindsey, J. C., Clifford, S. C., Eberhart, C. G., Cooper, M. K., Packer, R. J., Massimino, M., Garre, M. L., Bartels, U., Tabori, U., Hawkins, C. E., Dirks, P., Bouffet, E., Rutka, J. T., Wechsler-Reya, R. J., Weiss, W. A., Collier, L. S., Dupuy, A. J., Korshunov, A., Jones, D. T. W., Kool, M., Northcott, P. A., Pfister, S. M., Largaespada, D. A., Mungall, A. J., Moore, R. A., Jabado, N., Bader, G. D., Jones, S. J. M., Malkin, D., Marra, M. A. & Taylor, M. D., Jan 21 2016, In : Nature. 529, 7586, p. 351-357 7 p.

Research output: Contribution to journalArticle

144 Scopus citations
2 Scopus citations

Effect of price increase of adrenocorticotropic hormone on treatment practices of infantile spasms

Wray, C. D. & Benke, T. A., Sep 1 2010, In : Pediatric Neurology. 43, 3, p. 163-166 4 p.

Research output: Contribution to journalArticle

11 Scopus citations

EphrinB1 expression is dysregulated and promotes oncogenic signaling in medulloblastoma

McKinney, N., Yuan, L., Zhang, H., Liu, J., Cho, Y. J., Rushing, E., Schniederjan, M. & MacDonald, T. J., Jan 1 2015, In : Journal of Neuro-Oncology. 121, 1, p. 109-118 10 p.

Research output: Contribution to journalArticle

7 Scopus citations

Epigenetic antagonism between polycomb and SWI/SNF complexes during oncogenic transformation

Wilson, B. G., Wang, X., Shen, X., McKenna, E. S., Lemieux, M. E., Cho, Y. J., Koellhoffer, E. C., Pomeroy, S. L., Orkin, S. H. & Roberts, C. W. M., Oct 19 2010, In : Cancer Cell. 18, 4, p. 316-328 13 p.

Research output: Contribution to journalArticle

Open Access
313 Scopus citations

Epigenetic inactivation of the tumor suppressor BIN1 drives proliferation of SNF5-deficient tumors

McKenna, E. S., Tamayo, P., Cho, Y. J., Tillman, E. J., Mora-Blanco, E. L., Sansam, C. G., Koellhoffer, E. C., Pomeroy, S. L. & Roberts, C. W. M., May 15 2012, In : Cell Cycle. 11, 10, p. 1956-1965 10 p.

Research output: Contribution to journalArticle

Open Access
20 Scopus citations

Epigenetic targeting of Hedgehog pathway transcriptional output through BET bromodomain inhibition

Tang, Y., Gholamin, S., Schubert, S., Willardson, M. I., Lee, A., Bandopadhayay, P., Bergthold, G., Masoud, S., Nguyen, B., Vue, N., Balansay, B., Yu, F., Oh, S., Woo, P., Chen, S., Ponnuswami, A., Monje, M., Atwood, S. X., Whitson, R. J., Mitra, S. & 9 others, Cheshier, S. H., Qi, J., Beroukhim, R., Tang, J. Y., Wechsler-Reya, R., Oro, A. E., Link, B. A., Bradner, J. E. & Cho, Y. J., Jul 2014, In : Nature medicine. 20, 7, p. 732-740 9 p.

Research output: Contribution to journalArticle

162 Scopus citations

Epigenomic alterations define lethal CIMP-positive ependymomas of infancy

MacK, S. C., Witt, H., Piro, R. M., Gu, L., Zuyderduyn, S., Stütz, A. M., Wang, X., Gallo, M., Garzia, L., Zayne, K., Zhang, X., Ramaswamy, V., Jäger, N., Jones, D. T. W., Sill, M., Pugh, T. J., Ryzhova, M., Wani, K. M., Shih, D. J. H., Head, R. & 69 others, Remke, M., Bailey, S. D., Zichner, T., Faria, C. C., Barszczyk, M., Stark, S., Seker-Cin, H., Hutter, S., Johann, P., Bender, S., Hovestadt, V., Tzaridis, T., Dubuc, A. M., Northcott, P. A., Peacock, J., Bertrand, K. C., Agnihotri, S., Cavalli, F. M. G., Clarke, I., Nethery-Brokx, K., Creasy, C. L., Verma, S. K., Koster, J., Wu, X., Yao, Y., Milde, T., Sin-Chan, P., Zuccaro, J., Lau, L., Pereira, S., Castelo-Branco, P., Hirst, M., Marra, M. A., Roberts, S. S., Fults, D., Massimi, L., Cho, Y. J., Van Meter, T., Grajkowska, W., Lach, B., Kulozik, A. E., Von Deimling, A., Witt, O., Scherer, S. W., Fan, X., Muraszko, K. M., Kool, M., Pomeroy, S. L., Gupta, N., Phillips, J., Huang, A., Tabori, U., Hawkins, C., Malkin, D., Kongkham, P. N., Weiss, W. A., Jabado, N., Rutka, J. T., Bouffet, E., Korbel, J. O., Lupien, M., Aldape, K. D., Bader, G. D., Eils, R., Lichter, P., Dirks, P. B., Pfister, S. M., Korshunov, A. & Taylor, M. D., Feb 21 2014, In : Nature. 506, 7489, p. 445-450 6 p.

Research output: Contribution to journalArticle

308 Scopus citations

Expression of FoxM1 is required for the proliferation of medulloblastoma cells and indicates worse survival of patients

Priller, M., Pöschl, J., Abrão, L., Von Bueren, A., Cho, Y. J., Rutkowski, S., Kretzschmar, H. A. & Schüller, U., Nov 1 2011, In : Clinical Cancer Research. 17, 21, p. 6791-6801 11 p.

Research output: Contribution to journalArticle

Open Access
57 Scopus citations

Expression quantitative trait loci and receptor pharmacology implicate Arg1 and the GABA-A receptor as therapeutic targets in neuroblastoma

Hackett, C. S., Quigley, D. A., Wong, R. A., Chen, J., Cheng, C., Song, Y. K., Wei, J. S., Pawlikowska, L., Bao, Y., Goldenberg, D. D., Nguyen, K., Clay Gustafson, W., Rallapalli, S. K., Cho, Y. J., Cook, J. M., Kozlov, S., Mao, J. H., Van Dyke, T., Kwok, P. Y., Khan, J. & 3 others, Balmain, A., Fan, Q. W. & Weiss, W. A., Jan 1 2014, In : Cell Reports. 9, 3, p. 1034-1046 13 p.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Focal cortical dysplasia is more common in boys than in girls

Ortiz-González, X. R., Poduri, A., Roberts, C. M., Sullivan, J. E., Marsh, E. D. & Porter, B. E., Apr 1 2013, In : Epilepsy and Behavior. 27, 1, p. 121-123 3 p.

Research output: Contribution to journalArticle

12 Scopus citations

Focal seizure propagation in the intracranial EEG

Jenssen, S., Roberts, C. M., Gracely, E. J., Dlugos, D. J. & Sperling, M. R., Jan 1 2011, In : Epilepsy Research. 93, 1, p. 25-32 8 p.

Research output: Contribution to journalArticle

19 Scopus citations

Freehand placement of depth electrodes using electromagnetic frameless stereotactic guidance: Technical note

Wray, C. D., Kraemer, D. L., Yang, T., Poliachik, S. L., Ko, A. L., Poliakov, A., Hebb, A. O., Novotny, E. A. J. & Ojemann, J. G., Nov 1 2011, In : Journal of Neurosurgery: Pediatrics. 8, 5, p. 464-467 4 p.

Research output: Contribution to journalArticle

8 Scopus citations

Functional validation of the oncogenic cooperativity and targeting potential of tuberous sclerosis mutation in medulloblastoma using a MYC-amplified model cell line

Henderson, J. J., Wagner, J. P., Hofmann, N. E., Eide, C. A., Cho, Y-J., Druker, B. & Davare, M., 2017, (Accepted/In press) In : Pediatric Blood and Cancer.

Research output: Contribution to journalArticle

1 Scopus citations

Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition

Kool, M., Jones, D. T. W., Jäger, N., Northcott, P. A., Pugh, T. J., Hovestadt, V., Piro, R. M., Esparza, L. A., Markant, S. L., Remke, M., Milde, T., Bourdeaut, F., Ryzhova, M., Sturm, D., Pfaff, E., Stark, S., Hutter, S., Sxeker-Cin, H., Johann, P., Bender, S. & 56 others, Schmidt, C., Rausch, T., Shih, D., Reimand, J., Sieber, L., Wittmann, A., Linke, L., Witt, H., Weber, U. D., Zapatka, M., König, R., Beroukhim, R., Bergthold, G., Van Sluis, P., Volckmann, R., Koster, J., Versteeg, R., Schmidt, S., Wolf, S., Lawerenz, C., Bartholomae, C. C., Von Kalle, C., Unterberg, A., Herold-Mende, C., Hofer, S., Kulozik, A. E., Von Deimling, A., Scheurlen, W., Felsberg, J., Reifenberger, G., Hasselblatt, M., Crawford, J. R., Grant, G. A., Jabado, N., Perry, A., Cowdrey, C., Croul, S., Zadeh, G., Korbel, J. O., Doz, F., Delattre, O., Bader, G. D., McCabe, M. G., Collins, V. P., Kieran, M. W., Cho, Y. J., Pomeroy, S. L., Witt, O., Brors, B., Taylor, M. D., Schüller, U., Korshunov, A., Eils, R., Wechsler-Reya, R. J., Lichter, P. & Pfister, S. M., Mar 17 2014, In : Cancer Cell. 25, 3, p. 393-405 13 p.

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346 Scopus citations

Genomic analysis of diffuse pediatric low-grade gliomas identifies recurrent oncogenic truncating rearrangements in the transcription factor MYBL1

Ramkissoon, L. A., Horowitz, P. M., Craig, J. M., Ramkissoon, S. H., Rich, B. E., Schumacher, S. E., McKenna, A., Lawrence, M. S., Bergthold, G., Brastianos, P. K., Tabak, B., Ducar, M. D., Van Hummelen, P., MacConaill, L. E., Pouissant-Young, T., Cho, Y. J., Taha, H., Mahmoud, M., Bowers, D. C., Margraf, L. & 17 others, Tabori, U., Hawkins, C., Packer, R. J., Hill, D. A., Pomeroy, S. L., Eberhart, C. G., Dunn, I. F., Goumnerova, L., Getz, G., Chan, J. A., Santagata, S., Hahn, W. C., Stiles, C. D., Ligon, A. H., Kieran, M. W., Beroukhim, R. & Ligon, K. L., May 14 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 20, p. 8188-8193 6 p.

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117 Scopus citations

Growth factor receptor-Src-mediated suppression of GRK6 dysregulates CXCR4 signaling and promotes medulloblastoma migration

Yuan, L., Zhang, H., Liu, J., Rubin, J. B., Cho, Y. J., Shu, H. K., Schniederjan, M. & MacDonald, T. J., Mar 5 2013, In : Molecular Cancer. 12, 1, 18.

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22 Scopus citations

HDAC and PI3K Antagonists Cooperate to Inhibit Growth of MYC-Driven Medulloblastoma

Pei, Y., Liu, K. W., Wang, J., Garancher, A., Tao, R., Esparza, L. A., Maier, D. L., Udaka, Y. T., Murad, N., Morrissy, S., Seker-Cin, H., Brabetz, S., Qi, L., Kogiso, M., Schubert, S., Olson, J. M., Cho, Y. J., Li, X. N., Crawford, J. R., Levy, M. L. & 4 others, Kool, M., Pfister, S. M., Taylor, M. D. & Wechsler-Reya, R. J., Mar 14 2016, In : Cancer Cell. 29, 3, p. 311-323 13 p.

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77 Scopus citations

IGF1R as a Key Target in High Risk, Metastatic Medulloblastoma

Svalina, M. N., Kikuchi, K., Abraham, J., Lal, S., Davare, M., Settelmeyer, T. P., Young, M. C., Peckham, J. L., Cho, Y-J., Michalek, J. E., Hernandez, B. S., Berlow, N. E., Jackson, M., Guillaume, D. J., Selden, N., Bigner, D. D., Nazemi, K., Green, S. C., Corless, C., Gultekin, S. & 4 others, Mansoor, A., Rubin, B. P., Woltjer, R. R. & Keller, C., Jun 3 2016, In : Scientific Reports. 6, 27012.

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7 Scopus citations

Inhibition of TWIST1 leads to activation of oncogene-induced senescence in oncogene-driven non-small cell lung cancer

Burns, T. F., Dobromilskaya, I., Murphy, S. C., Gajula, R. P., Thiyagarajan, S., Chatley, S. N. H., Aziz, K., Cho, Y. J., Tran, P. T. & Rudin, C. M., Apr 1 2013, In : Molecular Cancer Research. 11, 4, p. 329-338 10 p.

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39 Scopus citations

Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome

Cho, Y. J., Tsherniak, A., Tamayo, P., Santagata, S., Ligon, A., Greulich, H., Berhoukim, R., Amani, V., Goumnerova, L., Eberhart, C. G., Lau, C. C., Olson, J. M., Gilbertson, R. J., Gajjar, A., Delattre, O., Kool, M., Ligon, K., Meyerson, M., Mesirov, J. P. & Pomeroy, S. L., Apr 10 2011, In : Journal of Clinical Oncology. 29, 11, p. 1424-1430 7 p.

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424 Scopus citations

Is postresective intraoperative electrocorticography predictive of seizure outcomes in children? Clinical article

Wray, C. D., McDaniel, S. S., Saneto, R. P., Novotny, E. J. & Ojemann, J. G., May 1 2012, In : Journal of Neurosurgery: Pediatrics. 9, 5, p. 546-551 6 p.

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24 Scopus citations

Loss of the epigenetic tumor suppressor snf5 leads to cancer without genomic instability

McKenna, E. S., Sansam, C. G., Cho, Y. J., Greulich, H., Evans, J. A., Thom, C. S., Moreau, L. A., Biegel, J. A., Pomeroy, S. L. & Roberts, C. W. M., Oct 1 2008, In : Molecular and cellular biology. 28, 20, p. 6223-6233 11 p.

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82 Scopus citations

Loss of the tumor suppressor Snf5 leads to aberrant activation of the Hedgehog-Gli pathway

Jagani, Z., Mora-Blanco, E. L., Sansam, C. G., McKenna, E. S., Wilson, B., Chen, D., Klekota, J., Tamayo, P., Nguyen, P. T. L., Tolstorukov, M., Park, P. J., Cho, Y. J., Hsiao, K., Buonamici, S., Pomeroy, S. L., Mesirov, J. P., Ruffner, H., Bouwmeester, T., Luchansky, S. J., Murtie, J. & 5 others, Kelleher, J. F., Warmuth, M., Sellers, W. R., Roberts, C. W. M. & Dorsch, M., Dec 1 2010, In : Nature medicine. 16, 12, p. 1429-1434 6 p.

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138 Scopus citations

Magnetic resonance imaging changes in a head and neck cancer patient with wernicke encephalopathy and visual loss

Lukas, R. V., Piantino, J., Ksiazek, S., Nichols, J., Cohen, E. E. W., Haraf, D., Bernard, J. & Rezania, K., Oct 1 2011, In : Neuro-Ophthalmology. 35, 5-6, p. 272-275 4 p.

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Medulloblastoma-associated DDX3 variant selectively alters the translational response to stress

Oh, S., Flynn, R. A., Floor, S. N., Purzner, J., Martin, L., Do, B. T., Schubert, S., Vaka, D., Morrissy, S., Li, Y., Kool, M., Hovestadt, V., Jones, D. T. W., Northcott, P. A., Risch, T., Warnatz, H. J., Yaspo, M. L., Adams, C. M., Leib, R. D., Breese, M. & 8 others, Marra, M. A., Malkin, D., Lichter, P., Doudna, J. A., Pfister, S. M., Taylor, M. D., Chang, H. Y. & Cho, Y. J., May 10 2016, In : Oncotarget. 7, 19, p. 28169-28182 14 p.

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23 Scopus citations