X-ray therapy of experimental malignant melanoma of the hamster eye

Robert P. Burns, Clifford V. Allen, Frederick (Fritz) Fraunfelder

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

There has been wide-spread disagreement about the effect of radiation in malignant melanoma. Therefore, the value of orthovoltage X-ray therapy to the eye of hamsters inoculated with five strains of malignant melanoma has been tested in controlled experiments. Tumor size and survival time were measured. X-ray therapy retarded melanoma growth at times. With some cell lines, X-ray therapy appeared to prolong hamster survival; with others, it did not. Neither X-ray therapy nor surgical enucleation of the eye appeared to be clearly superior.

Original languageEnglish (US)
Pages (from-to)328-336
Number of pages9
JournalAmerican Journal of Ophthalmology
Volume68
Issue number2
StatePublished - Aug 1969
Externally publishedYes

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X-Ray Therapy
Experimental Melanomas
Cricetinae
Melanoma
Eye Enucleation
Radiation Effects
Cell Line
Growth
Neoplasms

ASJC Scopus subject areas

  • Ophthalmology

Cite this

X-ray therapy of experimental malignant melanoma of the hamster eye. / Burns, Robert P.; Allen, Clifford V.; Fraunfelder, Frederick (Fritz).

In: American Journal of Ophthalmology, Vol. 68, No. 2, 08.1969, p. 328-336.

Research output: Contribution to journalArticle

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