Women and vulnerability to HAART non-adherence: A literature review of treatment adherence by gender from 2000 to 2011

Cathy M. Puskas, Jamie I. Forrest, Surita Parashar, Kate A. Salters, Angela M. Cescon, Angela Kaida, Cari L. Miller, David R. Bangsberg, Robert S. Hogg

Research output: Contribution to journalReview article

85 Scopus citations

Abstract

A literature review of original research articles on adherence to antiretroviral therapy (ART) in developed countries, covering January 2000 to June 2011, was conducted to determine if gender differences exist in the prevalence of nonadherence to ART. Of the 1,255 articles reviewed, only 189 included data on the proportion of the study population that was adherent and only 57 (30.2%) of these reported proportional adherence values by gender. While comparing articles was challenging because of varied reporting strategies, women generally exhibit poorer adherence than men. Thirty of the 44 articles (68.2%) that reported comparative data on adherence by gender found women to be less adherent than men. Ten articles (17.5%) reported significant differences in proportional adherence by gender, nine of which showed women to be less adherent than men. These findings suggest that in multiple studies from developed countries, female gender often predicts lower adherence. The unique circumstances of HIV-positive women require specialized care to increase adherence to ART.

Original languageEnglish (US)
Pages (from-to)277-287
Number of pages11
JournalCurrent HIV/AIDS Reports
Volume8
Issue number4
DOIs
StatePublished - Dec 1 2011
Externally publishedYes

Keywords

  • Adherence
  • Antiretroviral therapy
  • Gender
  • HIV
  • Patient compliance

ASJC Scopus subject areas

  • Virology
  • Infectious Diseases

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    Puskas, C. M., Forrest, J. I., Parashar, S., Salters, K. A., Cescon, A. M., Kaida, A., Miller, C. L., Bangsberg, D. R., & Hogg, R. S. (2011). Women and vulnerability to HAART non-adherence: A literature review of treatment adherence by gender from 2000 to 2011. Current HIV/AIDS Reports, 8(4), 277-287. https://doi.org/10.1007/s11904-011-0098-0