WNK-SPAK-NCC cascade revisited: WNK1 stimulates the activity of the Na-Cl cotransporter via SPAK, an effect antagonized by WNK4

María Chávez-Canales, Chong Zhang, Christelle Soukaseum, Erika Moreno, Diana Pacheco-Alvarez, Emmanuelle Vidal-Petiot, María Castañeda-Bueno, Norma Vázquez, Lorena Rojas-Vega, Nicholas P. Meermeier, Shaunessy Rogers, Xavier Jeunemaitre, Chao Ling Yang, David H. Ellison, Gerardo Gamba, Juliette Hadchouel

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Medicine & Life Sciences