Widespread porokeratotic adnexal ostial nevus: Clinical features and proposal of a new name unifying porokeratotic eccrine ostial and dermal duct nevus and porokeratotic eccrine and hair follicle nevus

Deborah S. Goddard, Maureen Rogers, Ilona J. Frieden, Alfons Krol, Clifton White, Anu G. Jayaraman, Leslie Robinson-Bostom, Anna L. Bruckner, Beth S. Ruben

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

Porokeratotic eccrine ostial and dermal duct nevus and a similar condition, porokeratotic eccrine and hair follicle nevus, are rare disorders of keratinization with eccrine and hair follicle involvement. We describe the clinical features in 5 patients, all of whom had widespread skin involvement following the lines of Blaschko. Two patients presented with erosions in the newborn period as the initial manifestation of their disease; one had an associated structural anomaly, unilateral breast hypoplasia; and one adult had malignant transformation in the nevus with development of multifocal squamous cell carcinomas. Three patients had histologic involvement of both acrosyringia and acrotrichia. Based on the observation of overlapping histologic features, we propose the name "porokeratotic adnexal ostial nevus" to incorporate the previously described entities porokeratotic eccrine ostial and dermal duct nevus and porokeratotic eccrine and hair follicle nevus.

Original languageEnglish (US)
JournalJournal of the American Academy of Dermatology
Volume61
Issue number6
DOIs
StatePublished - Dec 2009

Fingerprint

Hair Follicle
Nevus
Names
Skin
Squamous Cell Carcinoma
Breast
Observation
Newborn Infant

Keywords

  • malignant transformation
  • neonatal erosions
  • porokeratotic eccrine and hair follicle nevus
  • porokeratotic eccrine ostial and dermal duct nevus

ASJC Scopus subject areas

  • Dermatology

Cite this

Widespread porokeratotic adnexal ostial nevus : Clinical features and proposal of a new name unifying porokeratotic eccrine ostial and dermal duct nevus and porokeratotic eccrine and hair follicle nevus. / Goddard, Deborah S.; Rogers, Maureen; Frieden, Ilona J.; Krol, Alfons; White, Clifton; Jayaraman, Anu G.; Robinson-Bostom, Leslie; Bruckner, Anna L.; Ruben, Beth S.

In: Journal of the American Academy of Dermatology, Vol. 61, No. 6, 12.2009.

Research output: Contribution to journalArticle

Goddard, Deborah S. ; Rogers, Maureen ; Frieden, Ilona J. ; Krol, Alfons ; White, Clifton ; Jayaraman, Anu G. ; Robinson-Bostom, Leslie ; Bruckner, Anna L. ; Ruben, Beth S. / Widespread porokeratotic adnexal ostial nevus : Clinical features and proposal of a new name unifying porokeratotic eccrine ostial and dermal duct nevus and porokeratotic eccrine and hair follicle nevus. In: Journal of the American Academy of Dermatology. 2009 ; Vol. 61, No. 6.
@article{03e71b0385c44b149308d883da4dfea8,
title = "Widespread porokeratotic adnexal ostial nevus: Clinical features and proposal of a new name unifying porokeratotic eccrine ostial and dermal duct nevus and porokeratotic eccrine and hair follicle nevus",
abstract = "Porokeratotic eccrine ostial and dermal duct nevus and a similar condition, porokeratotic eccrine and hair follicle nevus, are rare disorders of keratinization with eccrine and hair follicle involvement. We describe the clinical features in 5 patients, all of whom had widespread skin involvement following the lines of Blaschko. Two patients presented with erosions in the newborn period as the initial manifestation of their disease; one had an associated structural anomaly, unilateral breast hypoplasia; and one adult had malignant transformation in the nevus with development of multifocal squamous cell carcinomas. Three patients had histologic involvement of both acrosyringia and acrotrichia. Based on the observation of overlapping histologic features, we propose the name {"}porokeratotic adnexal ostial nevus{"} to incorporate the previously described entities porokeratotic eccrine ostial and dermal duct nevus and porokeratotic eccrine and hair follicle nevus.",
keywords = "malignant transformation, neonatal erosions, porokeratotic eccrine and hair follicle nevus, porokeratotic eccrine ostial and dermal duct nevus",
author = "Goddard, {Deborah S.} and Maureen Rogers and Frieden, {Ilona J.} and Alfons Krol and Clifton White and Jayaraman, {Anu G.} and Leslie Robinson-Bostom and Bruckner, {Anna L.} and Ruben, {Beth S.}",
year = "2009",
month = "12",
doi = "10.1016/j.jaad.2009.03.036",
language = "English (US)",
volume = "61",
journal = "Journal of the American Academy of Dermatology",
issn = "0190-9622",
publisher = "Mosby Inc.",
number = "6",

}

TY - JOUR

T1 - Widespread porokeratotic adnexal ostial nevus

T2 - Clinical features and proposal of a new name unifying porokeratotic eccrine ostial and dermal duct nevus and porokeratotic eccrine and hair follicle nevus

AU - Goddard, Deborah S.

AU - Rogers, Maureen

AU - Frieden, Ilona J.

AU - Krol, Alfons

AU - White, Clifton

AU - Jayaraman, Anu G.

AU - Robinson-Bostom, Leslie

AU - Bruckner, Anna L.

AU - Ruben, Beth S.

PY - 2009/12

Y1 - 2009/12

N2 - Porokeratotic eccrine ostial and dermal duct nevus and a similar condition, porokeratotic eccrine and hair follicle nevus, are rare disorders of keratinization with eccrine and hair follicle involvement. We describe the clinical features in 5 patients, all of whom had widespread skin involvement following the lines of Blaschko. Two patients presented with erosions in the newborn period as the initial manifestation of their disease; one had an associated structural anomaly, unilateral breast hypoplasia; and one adult had malignant transformation in the nevus with development of multifocal squamous cell carcinomas. Three patients had histologic involvement of both acrosyringia and acrotrichia. Based on the observation of overlapping histologic features, we propose the name "porokeratotic adnexal ostial nevus" to incorporate the previously described entities porokeratotic eccrine ostial and dermal duct nevus and porokeratotic eccrine and hair follicle nevus.

AB - Porokeratotic eccrine ostial and dermal duct nevus and a similar condition, porokeratotic eccrine and hair follicle nevus, are rare disorders of keratinization with eccrine and hair follicle involvement. We describe the clinical features in 5 patients, all of whom had widespread skin involvement following the lines of Blaschko. Two patients presented with erosions in the newborn period as the initial manifestation of their disease; one had an associated structural anomaly, unilateral breast hypoplasia; and one adult had malignant transformation in the nevus with development of multifocal squamous cell carcinomas. Three patients had histologic involvement of both acrosyringia and acrotrichia. Based on the observation of overlapping histologic features, we propose the name "porokeratotic adnexal ostial nevus" to incorporate the previously described entities porokeratotic eccrine ostial and dermal duct nevus and porokeratotic eccrine and hair follicle nevus.

KW - malignant transformation

KW - neonatal erosions

KW - porokeratotic eccrine and hair follicle nevus

KW - porokeratotic eccrine ostial and dermal duct nevus

UR - http://www.scopus.com/inward/record.url?scp=71549121638&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=71549121638&partnerID=8YFLogxK

U2 - 10.1016/j.jaad.2009.03.036

DO - 10.1016/j.jaad.2009.03.036

M3 - Article

C2 - 19664847

AN - SCOPUS:71549121638

VL - 61

JO - Journal of the American Academy of Dermatology

JF - Journal of the American Academy of Dermatology

SN - 0190-9622

IS - 6

ER -