Whole-body FDG PET-MR oncologic imaging: pitfalls in clinical interpretation related to inaccurate MR-based attenuation correction

Ulrike Attenberger, Ciprian Catana, Hersh Chandarana, Onofrio A. Catalano, Kent Friedman, Stefan A. Schonberg, James Thrall, Marco Salvatore, Bruce R. Rosen, Alexander Guimaraes

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Simultaneous data collection for positron emission tomography and magnetic resonance imaging (PET/MR) is now a reality. While the full benefits of concurrently acquiring PET and MR data and the potential added clinical value are still being evaluated, initial studies have identified several important potential pitfalls in the interpretation of fluorodeoxyglucose (FDG) PET/MRI in oncologic whole-body imaging, the majority of which being related to the errors in the attenuation maps created from the MR data. The purpose of this article was to present such pitfalls and artifacts using case examples, describe their etiology, and discuss strategies to overcome them. Using a case-based approach, we will illustrate artifacts related to (1) Inaccurate bone tissue segmentation; (2) Inaccurate air cavities segmentation; (3) Motion-induced misregistration; (4) RF coils in the PET field of view; (5) B0 field inhomogeneity; (6) B1 field inhomogeneity; (7) Metallic implants; (8) MR contrast agents.

Original languageEnglish (US)
Pages (from-to)1374-1386
Number of pages13
JournalAbdominal Imaging
Volume40
Issue number6
DOIs
StatePublished - May 30 2015

Fingerprint

Artifacts
Whole Body Imaging
Positron-Emission Tomography
Contrast Media
Air
Magnetic Resonance Imaging
Bone and Bones

Keywords

  • Attenuation correction
  • PET/MRI
  • Pitfalls

ASJC Scopus subject areas

  • Gastroenterology
  • Urology
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Whole-body FDG PET-MR oncologic imaging : pitfalls in clinical interpretation related to inaccurate MR-based attenuation correction. / Attenberger, Ulrike; Catana, Ciprian; Chandarana, Hersh; Catalano, Onofrio A.; Friedman, Kent; Schonberg, Stefan A.; Thrall, James; Salvatore, Marco; Rosen, Bruce R.; Guimaraes, Alexander.

In: Abdominal Imaging, Vol. 40, No. 6, 30.05.2015, p. 1374-1386.

Research output: Contribution to journalArticle

Attenberger, U, Catana, C, Chandarana, H, Catalano, OA, Friedman, K, Schonberg, SA, Thrall, J, Salvatore, M, Rosen, BR & Guimaraes, A 2015, 'Whole-body FDG PET-MR oncologic imaging: pitfalls in clinical interpretation related to inaccurate MR-based attenuation correction', Abdominal Imaging, vol. 40, no. 6, pp. 1374-1386. https://doi.org/10.1007/s00261-015-0455-3
Attenberger, Ulrike ; Catana, Ciprian ; Chandarana, Hersh ; Catalano, Onofrio A. ; Friedman, Kent ; Schonberg, Stefan A. ; Thrall, James ; Salvatore, Marco ; Rosen, Bruce R. ; Guimaraes, Alexander. / Whole-body FDG PET-MR oncologic imaging : pitfalls in clinical interpretation related to inaccurate MR-based attenuation correction. In: Abdominal Imaging. 2015 ; Vol. 40, No. 6. pp. 1374-1386.
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