West Nile virus infection activates the unfolded protein response, leading to CHOP induction and apoptosis

Agriculture & Biology

• unfolded protein response 93%
• West Nile virus 88%
• apoptosis 64%
• infection 36%
• transcription factors 13%
• virus replication 12%
• fibroblasts 10%
• phosphorylation 10%
• binding proteins 10%
• NAD ADP-ribosyltransferase 8%
• chops 7%
• meningitis 7%
• endoplasmic reticulum stress 7%
• caspase-3 7%
• response elements 7%
• encephalitis 6%
• proteasome endopeptidase complex 6%
• viral load 6%
• mice 6%
• inositols 6%
• defense mechanisms 5%
• DNA damage 5%
• cyclic AMP 5%
• protein kinases 5%
• cells 5%
• cell death 5%
• endoplasmic reticulum 5%
• phosphotransferases (kinases) 4%
• cleavage (chemistry) 4%
• neurons 4%
• death 4%
• genes 4%
• proteins 3%
• phenotype 3%
• rats 3%
• enzymes 2%
• tissues 2%

Medicine & Life Sciences

• West Nile Fever 100%
• Unfolded Protein Response 86%
• Apoptosis 42%
• Activating Transcription Factor 6 18%
• X-Box Binding Protein 1 18%
• Eukaryotic Initiation Factor-2 17%
• Fibroblasts 8%
• Phosphorylation 8%
• Poly(ADP-ribose) Polymerases 6%
• Premature Mortality 6%
• Inositol 6%
• Response Elements 6%
• Encephalitis 6%
• Proteasome Endopeptidase Complex 6%
• Virus Replication 5%
• Meningitis 5%
• Neuroblastoma 5%
• Endoplasmic Reticulum 5%
• Protein Kinases 5%
• Caspase 3 5%
• DNA Damage 5%
• Genes 4%
• Phosphotransferases 4%
• Cell Death 4%
• Transcription Factors 4%
• Proteins 4%
• Neurons 3%
• Phenotype 3%
• Messenger RNA 3%
• Enzymes 3%
• Growth 2%