Weight gain on androgen deprivation therapy: Which patients are at highest risk?

Daniel M. Seible, Xiangmei Gu, Andrew S. Hyatt, Clair J. Beard, Toni K. Choueiri, Jason A. Efstathiou, David T. Miyamoto, Timur Mitin, Neil E. Martin, Christopher J. Sweeney, Quoc Dien Trinh, Joshua A. Beckman, Shehzad Basaria, Paul L. Nguyen

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

Objective To identify factors associated with weight gain at 1 year from initiation of androgen deprivation therapy (ADT). Methods A retrospective review assessed weight change among 118 men with nonmetastatic prostate cancer treated with ADT for at least 6 months. Outcome associations were tested using 2-tailed t tests and linear regression. Results Men in our cohort had significant weight gain (+1.32 kg, P =.0005) in the 1 year after ADT initiation. Three risk factors for weight gain on ADT were identified as follows: age

Original languageEnglish (US)
Pages (from-to)1316-1321
Number of pages6
JournalUrology
Volume83
Issue number6
DOIs
Publication statusPublished - 2014
Externally publishedYes

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ASJC Scopus subject areas

  • Urology

Cite this

Seible, D. M., Gu, X., Hyatt, A. S., Beard, C. J., Choueiri, T. K., Efstathiou, J. A., ... Nguyen, P. L. (2014). Weight gain on androgen deprivation therapy: Which patients are at highest risk? Urology, 83(6), 1316-1321. https://doi.org/10.1016/j.urology.2014.02.006