Weigh the benefits of treatment against the increase in the risk of falls when using antidepressant therapy in the elderly

N. Van Der Velde, W. Meerding, C. Looman, P. Kannus, H. Sievnen, M. Palvanen, A. Darowski, S. Chambers, D. Chambers, P. Thapa, P. Gideon, T. Cost, R. Hubbard, P. Farrington, C. Smith, P. Vestergaard, L. Rejnmark, L. Mosekilde, W. Ray, M. GriffinE. Malcolm, S. Goldman, K. Stone, S. Ancoli-Israel, R. Asplund, S. Henriksson, S. Johansson, R. Asplund, S. Johansson, S. Henriksson, K. Ensrud, T. Blackwell, S. Ancoli-Israel, J. Teo, N. Briffa, A. Devine, A. Mayers, D. Baldwin, X. Li, R. Hamdy, W. Sandborn, D. Fairweather, J. Kerr, D. Harrison, B. Takkouche, A. Montes-Martnez, S. Gill, E. Haney, B. Chan, S. Diem

Research output: Contribution to journalShort survey

Abstract

The risk of falls increases in elderly patients receiving treatment with antidepressants. The increased risk is probably attributable to the adverse effects (e.g. sedation, sleep disturbances and subsequent daytime drowsiness, balance problems, orthostatic hypotension and cardiac rhythm disorders) associated with antidepressants.

Original languageEnglish (US)
Pages (from-to)23-26
Number of pages4
JournalDrugs and Therapy Perspectives
Volume26
Issue number2
DOIs
StatePublished - Jan 21 2010

Keywords

  • Adrenergic-receptor-antagonists
  • Adverse reactions
  • Antidepressants
  • Elderly
  • Insomnia
  • Monoamine-oxidase-inhibitors
  • Orthostatic-hypotension
  • Sedation
  • Serotonin-uptake-inhibitors

ASJC Scopus subject areas

  • Pharmacology (medical)

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  • Cite this

    Van Der Velde, N., Meerding, W., Looman, C., Kannus, P., Sievnen, H., Palvanen, M., Darowski, A., Chambers, S., Chambers, D., Thapa, P., Gideon, P., Cost, T., Hubbard, R., Farrington, P., Smith, C., Vestergaard, P., Rejnmark, L., Mosekilde, L., Ray, W., ... Diem, S. (2010). Weigh the benefits of treatment against the increase in the risk of falls when using antidepressant therapy in the elderly. Drugs and Therapy Perspectives, 26(2), 23-26. https://doi.org/10.2165/11204060-000000000-00000