Water balance in very low-birth-weight infants

Relationship to water and sodium intake and effect on outcome

John M. Lorenz, Leonard I. Kleinman, Uma R. Kotagal, Mark Reller

Research output: Contribution to journalArticle

120 Citations (Scopus)

Abstract

The clinical effects of fluid therapy designed to maintain different degrees of negative water balance during the first five days of life were determined prospectively in 88 very low-birth-weight infants. Infants with birth weights of 750 to 1,500 gm were matched for birth weight in 250 gm increments, RDS or no RDS, asphyxiated or not, and inborn or outborn. Each infant was randomized to either Group 1-fluids managed to allow 1 to 2% loss of BW per day to a maximum loss of 8 to 10%, or Group 2-fluids managed to allow 3 to 5% loss of BW per day to a maximum loss of 13 to 15%. The mean five-day cumulative fluid input in Group 2 was 220 ml/kg less than in Group 1, yet Group 2 lost only 41 gm/kg more than did Group 1 (8.8% of BW lost in Group 1 vs 12.9% of BW lost in Group 2, P

Original languageEnglish (US)
Pages (from-to)423-432
Number of pages10
JournalThe Journal of Pediatrics
Volume101
Issue number3
DOIs
StatePublished - 1982
Externally publishedYes

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Very Low Birth Weight Infant
Birth Weight
Drinking
Sodium
Water
Fluid Therapy

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Water balance in very low-birth-weight infants : Relationship to water and sodium intake and effect on outcome. / Lorenz, John M.; Kleinman, Leonard I.; Kotagal, Uma R.; Reller, Mark.

In: The Journal of Pediatrics, Vol. 101, No. 3, 1982, p. 423-432.

Research output: Contribution to journalArticle

Lorenz, John M. ; Kleinman, Leonard I. ; Kotagal, Uma R. ; Reller, Mark. / Water balance in very low-birth-weight infants : Relationship to water and sodium intake and effect on outcome. In: The Journal of Pediatrics. 1982 ; Vol. 101, No. 3. pp. 423-432.
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