Watching one's P's and, Q's: Promiscuity, plasticity, and quasiequivalence in a T = 1 virus

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Although quasiequivalence is not needed to explain the assembly of the T = 1 canine parvovirus capsid, the interactions of the 60-fold symmetrical capsid protein with less symmetrical vital components illustrate the elements of plasticity and promiscuity of interactions that are embodied in quasiequivalence. The current analysis is based on interactions of fivefold related proteins with a single peptide running along the fivefold axis, and on interactions of the capsid protein with various fragments of the genomic DNA, each having a different sequence and exposing the protein to interactions with different types of nucleotide base.

Original languageEnglish (US)
Pages (from-to)639-644
Number of pages6
JournalBiophysical Journal
Volume74
Issue number1
StatePublished - Jan 1998
Externally publishedYes

Fingerprint

Capsid Proteins
Canine Parvovirus
Viruses
Capsid
Proteins
Nucleotides
Peptides
DNA

ASJC Scopus subject areas

  • Biophysics

Cite this

Watching one's P's and, Q's : Promiscuity, plasticity, and quasiequivalence in a T = 1 virus. / Chapman, Michael.

In: Biophysical Journal, Vol. 74, No. 1, 01.1998, p. 639-644.

Research output: Contribution to journalArticle

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