Warfarin-induced skin necrosis mimicking calciphylaxis: A case report and review of the literature

Gina Chacon, Timmy Nguyen, Akram Khan, Animesh Sinha, Supriya Maddirala

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13 Scopus citations


Warfarin-induced skin necrosis (WISN) and calciphylaxis share similar early clinical findings and can both lead to significant morbidity and mortality. The authors reviewed the literature on both conditions and describe a case of extensive skin necrosis in a patient with end-stage renal disease who was initially suspected to have calciphylaxis. Further investigation supported a diagnosis of WISN. The pathogenesis, clinical manifestations and treatment of WISN and calciphylaxis are discussed, with emphasis on a diagnostic approach for early recognition.

Original languageEnglish (US)
Pages (from-to)859-863
Number of pages5
JournalJournal of Drugs in Dermatology
Issue number7
StatePublished - Jul 1 2010


ASJC Scopus subject areas

  • Dermatology

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