von Hippel-Lindau Disease: Angiomatosis of the Retina and Central Nervous System

Glenn L. Wing; John J. Weiter; Peter J. Kelly; Daniel M. Albert; John R. Gonder

doi:10.1016/S0161-6420(81)34858-1

von Hippel-Lindau Disease: Angiomatosis of the Retina and Central Nervous System

Glenn L. Wing, John J. Weiter, Peter J. Kelly, Daniel M. Albert, John R. Gonder

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Abstract

von Hippel-Lindau disease is a phakomatosis that is characterized by multiple angiomatous hamartomas located in the retina, central nervous system (CNS), and visceral organs. Retinal angiomas causing blindness and CNS angiomas causing death are familiar consequences of this disease. In certain cases, early detection and treatment of these lesions may prevent their disastrous effects. Since this disease is considered to have an autosomal dominant inheritance pattern, the physician should initiate a systematic examination of all the patient’s family members.

Original language	English (US)
Pages (from-to)	1311-1314
Number of pages	4
Journal	Ophthalmology
Volume	88
Issue number	12
DOIs	https://doi.org/10.1016/S0161-6420(81)34858-1
State	Published - 1981
Externally published	Yes

Keywords

angiomatous hamartoma
foam cell
hemangioblastoma
phakoma

ASJC Scopus subject areas

Ophthalmology

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10.1016/S0161-6420(81)34858-1

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title = "von Hippel-Lindau Disease: Angiomatosis of the Retina and Central Nervous System",

abstract = "von Hippel-Lindau disease is a phakomatosis that is characterized by multiple angiomatous hamartomas located in the retina, central nervous system (CNS), and visceral organs. Retinal angiomas causing blindness and CNS angiomas causing death are familiar consequences of this disease. In certain cases, early detection and treatment of these lesions may prevent their disastrous effects. Since this disease is considered to have an autosomal dominant inheritance pattern, the physician should initiate a systematic examination of all the patient{\textquoteright}s family members.",

keywords = "angiomatous hamartoma, foam cell, hemangioblastoma, phakoma",

author = "Wing, {Glenn L.} and Weiter, {John J.} and Kelly, {Peter J.} and Albert, {Daniel M.} and Gonder, {John R.}",

note = "Funding Information: From the Eye Research Institute of Retina Foundation, and the Retina Associates, Boston, Massachusetts;* and the Harvard Medical School, Massachusetts Eye and Ear Infirmary, Howe Laboratory of Ophthalmology, Boston, Massachusetts. t Supported in part by the Massachusetts Lions Eye Research Fund, Inc., and Biomedical Research Support Grant 2 SOl RR05485-18. Reprint requests to Daniel M. Albert, MD, Eye Research Institute, 20 Staniford Street, Boston, MA 02119.",

year = "1981",

doi = "10.1016/S0161-6420(81)34858-1",

language = "English (US)",

volume = "88",

pages = "1311--1314",

journal = "Ophthalmology",

issn = "0161-6420",

publisher = "Elsevier Inc.",

number = "12",

}

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T1 - von Hippel-Lindau Disease

T2 - Angiomatosis of the Retina and Central Nervous System

AU - Wing, Glenn L.

AU - Weiter, John J.

AU - Kelly, Peter J.

AU - Albert, Daniel M.

AU - Gonder, John R.

N1 - Funding Information: From the Eye Research Institute of Retina Foundation, and the Retina Associates, Boston, Massachusetts;* and the Harvard Medical School, Massachusetts Eye and Ear Infirmary, Howe Laboratory of Ophthalmology, Boston, Massachusetts. t Supported in part by the Massachusetts Lions Eye Research Fund, Inc., and Biomedical Research Support Grant 2 SOl RR05485-18. Reprint requests to Daniel M. Albert, MD, Eye Research Institute, 20 Staniford Street, Boston, MA 02119.

PY - 1981

Y1 - 1981

N2 - von Hippel-Lindau disease is a phakomatosis that is characterized by multiple angiomatous hamartomas located in the retina, central nervous system (CNS), and visceral organs. Retinal angiomas causing blindness and CNS angiomas causing death are familiar consequences of this disease. In certain cases, early detection and treatment of these lesions may prevent their disastrous effects. Since this disease is considered to have an autosomal dominant inheritance pattern, the physician should initiate a systematic examination of all the patient’s family members.

AB - von Hippel-Lindau disease is a phakomatosis that is characterized by multiple angiomatous hamartomas located in the retina, central nervous system (CNS), and visceral organs. Retinal angiomas causing blindness and CNS angiomas causing death are familiar consequences of this disease. In certain cases, early detection and treatment of these lesions may prevent their disastrous effects. Since this disease is considered to have an autosomal dominant inheritance pattern, the physician should initiate a systematic examination of all the patient’s family members.

KW - angiomatous hamartoma

KW - foam cell

KW - hemangioblastoma

KW - phakoma

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AN - SCOPUS:0019849311

SN - 0161-6420

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JO - Ophthalmology

JF - Ophthalmology

IS - 12

ER -

von Hippel-Lindau Disease: Angiomatosis of the Retina and Central Nervous System

Abstract

Keywords

ASJC Scopus subject areas

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