Vitiligo and disorders of the retinal pigment epithelium

D. M. Albert, M. D. Wagoner, R. C. Pruett, J. J. Nordlund, A. B. Lerner

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Abstract

The association of vitiligo with inflammation of the uveal tract is well established. The relationship between vitiligo and hypopigmentation and/or degeneration of the retinal pigment epithelium (RPE) not secondary to ocular inflammation has not been adequately investigated. Sixty (27%) of 223 consecutive patients with vitiligo were found to have some evidence of RPE phypopigmentation ranging from mild, focal areas of involvement in most cases to extensive RPE degeneration with a retinitis pigmentosa-like syndrome in one patient. Fifteen (25%) patients complained of night blindness. Only 6 (4%) of 148 patients in a control group had similar fundoscopic findings (p<0.001). None of these patients were symptomatic. There have been isolated reports of vitiligo occurring with tapetoretinal degeneration. We report 2 patients with both vitiligo and retinitis pigmentosa.

Original languageEnglish (US)
Pages (from-to)153-156
Number of pages4
JournalUnknown Journal
Volume67
Issue number3
DOIs
StatePublished - Jan 1 1983

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ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

Cite this

Albert, D. M., Wagoner, M. D., Pruett, R. C., Nordlund, J. J., & Lerner, A. B. (1983). Vitiligo and disorders of the retinal pigment epithelium. Unknown Journal, 67(3), 153-156. https://doi.org/10.1136/bjo.67.3.153