TY - JOUR
T1 - Viral pneumonias in adults
T2 - Radiologic and pathologic findings
AU - Kim, Eun A.
AU - Lee, Kyung Soo
AU - Primack, Steven L.
AU - Hye, Kyung Yoon
AU - Hong, Sik Byun
AU - Tae, Sung Kim
AU - Gee, Young Suh
AU - Kwon, O. Jung
AU - Han, Joungho
PY - 2002
Y1 - 2002
N2 - Numerous viruses, including influenza virus, measles virus, Hantavirus, adenovirus, herpesviruses, varicella-zoster virus, cytomegalovirus, and Epstein-Barr virus, can cause lower respiratory tract infection in adults. Viral pneumonia in adults can be classified into two clinical groups: so-called atypical pneumonia in otherwise healthy hosts and viral pneumonia in immunocompromised hosts. Influenza virus types A and B cause most cases of viral pneumonia in immunocompetent adults. Immunocompromised hosts are susceptible to pneumonias caused by cytomegalovirus, herpesviruses, measles virus, and adenovirus. The radiographic findings, which consist mainly of patchy or diffuse ground-glass opacity with or without consolidation and reticular areas of increased opacity, are variable and overlapping. Computed tomographic findings, which are also overlapping, consist of poorly defined centrilobular nodules, ground-glass attenuation with a lobular distribution, segmental consolidation, or diffuse ground-glass attenuation with thickened interlobular septa. The radiologic findings reflect the variable extents of the histopathologic features: diffuse alveolar damage (intraalveolar edema, fibrin, and variable cellular infiltrates with a hyaline membrane), intraalveolar hemorrhage, and interstitial (intrapulmonary or airway) inflammatory cell infiltration. Clinical information such as patient age, immune status, community outbreaks, symptom onset and duration, and presence of a rash remain important aids in diagnosis of viral causes.
AB - Numerous viruses, including influenza virus, measles virus, Hantavirus, adenovirus, herpesviruses, varicella-zoster virus, cytomegalovirus, and Epstein-Barr virus, can cause lower respiratory tract infection in adults. Viral pneumonia in adults can be classified into two clinical groups: so-called atypical pneumonia in otherwise healthy hosts and viral pneumonia in immunocompromised hosts. Influenza virus types A and B cause most cases of viral pneumonia in immunocompetent adults. Immunocompromised hosts are susceptible to pneumonias caused by cytomegalovirus, herpesviruses, measles virus, and adenovirus. The radiographic findings, which consist mainly of patchy or diffuse ground-glass opacity with or without consolidation and reticular areas of increased opacity, are variable and overlapping. Computed tomographic findings, which are also overlapping, consist of poorly defined centrilobular nodules, ground-glass attenuation with a lobular distribution, segmental consolidation, or diffuse ground-glass attenuation with thickened interlobular septa. The radiologic findings reflect the variable extents of the histopathologic features: diffuse alveolar damage (intraalveolar edema, fibrin, and variable cellular infiltrates with a hyaline membrane), intraalveolar hemorrhage, and interstitial (intrapulmonary or airway) inflammatory cell infiltration. Clinical information such as patient age, immune status, community outbreaks, symptom onset and duration, and presence of a rash remain important aids in diagnosis of viral causes.
KW - Lung, infection, 60.206
KW - Pneumonia, 60.21
KW - Viruses, 60.206, 60.2062, 60.2063, 60.2064, 60.2065, 60.2066, 60.2069
UR - http://www.scopus.com/inward/record.url?scp=0036778007&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0036778007&partnerID=8YFLogxK
U2 - 10.1148/radiographics.22.suppl_1.g02oc15s137
DO - 10.1148/radiographics.22.suppl_1.g02oc15s137
M3 - Article
C2 - 12376607
AN - SCOPUS:0036778007
VL - 22
SP - s137-s149
JO - Radiographics
JF - Radiographics
SN - 0271-5333
IS - SPEC. ISS
ER -