Viral pneumonias in adults: Radiologic and pathologic findings

Eun A. Kim, Kyung Soo Lee, Steven Primack, Kyung Yoon Hye, Sik Byun Hong, Sung Kim Tae, Young Suh Gee, O. Jung Kwon, Joungho Han

Research output: Contribution to journalArticle

192 Citations (Scopus)

Abstract

Numerous viruses, including influenza virus, measles virus, Hantavirus, adenovirus, herpesviruses, varicella-zoster virus, cytomegalovirus, and Epstein-Barr virus, can cause lower respiratory tract infection in adults. Viral pneumonia in adults can be classified into two clinical groups: so-called atypical pneumonia in otherwise healthy hosts and viral pneumonia in immunocompromised hosts. Influenza virus types A and B cause most cases of viral pneumonia in immunocompetent adults. Immunocompromised hosts are susceptible to pneumonias caused by cytomegalovirus, herpesviruses, measles virus, and adenovirus. The radiographic findings, which consist mainly of patchy or diffuse ground-glass opacity with or without consolidation and reticular areas of increased opacity, are variable and overlapping. Computed tomographic findings, which are also overlapping, consist of poorly defined centrilobular nodules, ground-glass attenuation with a lobular distribution, segmental consolidation, or diffuse ground-glass attenuation with thickened interlobular septa. The radiologic findings reflect the variable extents of the histopathologic features: diffuse alveolar damage (intraalveolar edema, fibrin, and variable cellular infiltrates with a hyaline membrane), intraalveolar hemorrhage, and interstitial (intrapulmonary or airway) inflammatory cell infiltration. Clinical information such as patient age, immune status, community outbreaks, symptom onset and duration, and presence of a rash remain important aids in diagnosis of viral causes.

Original languageEnglish (US)
JournalRadiographics
Volume22
Issue numberSPEC. ISS
StatePublished - 2002

Fingerprint

Viral Pneumonia
Glass
Measles virus
Herpesviridae
Immunocompromised Host
Cytomegalovirus
Adenoviridae
Pneumonia
Hantavirus
Influenza B virus
Human Herpesvirus 3
Hyalin
Influenza A virus
Exanthema
Orthomyxoviridae
Fibrin
Human Herpesvirus 4
Respiratory Tract Infections
Disease Outbreaks
Edema

Keywords

  • Lung, infection, 60.206
  • Pneumonia, 60.21
  • Viruses, 60.206, 60.2062, 60.2063, 60.2064, 60.2065, 60.2066, 60.2069

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Kim, E. A., Lee, K. S., Primack, S., Hye, K. Y., Hong, S. B., Tae, S. K., ... Han, J. (2002). Viral pneumonias in adults: Radiologic and pathologic findings. Radiographics, 22(SPEC. ISS).

Viral pneumonias in adults : Radiologic and pathologic findings. / Kim, Eun A.; Lee, Kyung Soo; Primack, Steven; Hye, Kyung Yoon; Hong, Sik Byun; Tae, Sung Kim; Gee, Young Suh; Kwon, O. Jung; Han, Joungho.

In: Radiographics, Vol. 22, No. SPEC. ISS, 2002.

Research output: Contribution to journalArticle

Kim, EA, Lee, KS, Primack, S, Hye, KY, Hong, SB, Tae, SK, Gee, YS, Kwon, OJ & Han, J 2002, 'Viral pneumonias in adults: Radiologic and pathologic findings', Radiographics, vol. 22, no. SPEC. ISS.
Kim EA, Lee KS, Primack S, Hye KY, Hong SB, Tae SK et al. Viral pneumonias in adults: Radiologic and pathologic findings. Radiographics. 2002;22(SPEC. ISS).
Kim, Eun A. ; Lee, Kyung Soo ; Primack, Steven ; Hye, Kyung Yoon ; Hong, Sik Byun ; Tae, Sung Kim ; Gee, Young Suh ; Kwon, O. Jung ; Han, Joungho. / Viral pneumonias in adults : Radiologic and pathologic findings. In: Radiographics. 2002 ; Vol. 22, No. SPEC. ISS.
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