Very old adults with better memory function have higher low-density lipoprotein cholesterol levels and lower triglyceride to high-density lipoprotein cholesterol ratios: KOCOA project

Yuriko Katsumata; Hidemi Todoriki; Yasushi Higashiuesato; Shotoku Yasura; Yusuke Ohya; D. Craig Willcox; Hiroko H. Dodge

doi:10.3233/JAD-121138

Very old adults with better memory function have higher low-density lipoprotein cholesterol levels and lower triglyceride to high-density lipoprotein cholesterol ratios: KOCOA project

Yuriko Katsumata, Hidemi Todoriki, Yasushi Higashiuesato, Shotoku Yasura, Yusuke Ohya, D. Craig Willcox, Hiroko H. Dodge

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

We cross-sectionally examined which lipid profiles are associated with better cognitive function among those aged 80 and older, free of dementia (Clinical Dementia Rating ≤0.5), functionally independent, and community-dwelling. Our cohort consisted of 193 participants from the 'Keys to Optimal Cognitive Aging (KOCOA) Project', a prospective cohort study in Okinawa, Japan. Higher low-density lipoprotein cholesterol levels and lower triglyceride/high-density lipoprotein cholesterol (TG/HDL-C) ratios were associated with higher scores in memory performance after controlling for confounders. Further research is required to clarify the associations among LDL-C levels, TG/HDL-C ratios, and healthy cognitive aging.

Original language	English (US)
Pages (from-to)	273-279
Number of pages	7
Journal	Journal of Alzheimer's Disease
Volume	34
Issue number	1
DOIs	https://doi.org/10.3233/JAD-121138
State	Published - 2013
Externally published	Yes

Keywords

Aged 80 and over
lipoprotein cholesterol
memory disorders

ASJC Scopus subject areas

General Neuroscience
Clinical Psychology
Geriatrics and Gerontology
Psychiatry and Mental health

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10.3233/JAD-121138

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Katsumata, Y., Todoriki, H., Higashiuesato, Y., Yasura, S., Ohya, Y., Willcox, D. C., & Dodge, H. H. (2013). Very old adults with better memory function have higher low-density lipoprotein cholesterol levels and lower triglyceride to high-density lipoprotein cholesterol ratios: KOCOA project. Journal of Alzheimer's Disease, 34(1), 273-279. https://doi.org/10.3233/JAD-121138

Very old adults with better memory function have higher low-density lipoprotein cholesterol levels and lower triglyceride to high-density lipoprotein cholesterol ratios: KOCOA project. / Katsumata, Yuriko; Todoriki, Hidemi; Higashiuesato, Yasushi et al.
In: Journal of Alzheimer's Disease, Vol. 34, No. 1, 2013, p. 273-279.

Research output: Contribution to journal › Article › peer-review

Katsumata, Y, Todoriki, H, Higashiuesato, Y, Yasura, S, Ohya, Y, Willcox, DC & Dodge, HH 2013, 'Very old adults with better memory function have higher low-density lipoprotein cholesterol levels and lower triglyceride to high-density lipoprotein cholesterol ratios: KOCOA project', Journal of Alzheimer's Disease, vol. 34, no. 1, pp. 273-279. https://doi.org/10.3233/JAD-121138

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Very old adults with better memory function have higher low-density lipoprotein cholesterol levels and lower triglyceride to high-density lipoprotein cholesterol ratios: KOCOA project

Abstract

Keywords

ASJC Scopus subject areas

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