Very old adults with better memory function have higher low-density lipoprotein cholesterol levels and lower triglyceride to high-density lipoprotein cholesterol ratios: KOCOA project

Yuriko Katsumata, Hidemi Todoriki, Yasushi Higashiuesato, Shotoku Yasura, Yusuke Ohya, D. Craig Willcox, Hiroko Dodge

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

We cross-sectionally examined which lipid profiles are associated with better cognitive function among those aged 80 and older, free of dementia (Clinical Dementia Rating ≤0.5), functionally independent, and community-dwelling. Our cohort consisted of 193 participants from the 'Keys to Optimal Cognitive Aging (KOCOA) Project', a prospective cohort study in Okinawa, Japan. Higher low-density lipoprotein cholesterol levels and lower triglyceride/high-density lipoprotein cholesterol (TG/HDL-C) ratios were associated with higher scores in memory performance after controlling for confounders. Further research is required to clarify the associations among LDL-C levels, TG/HDL-C ratios, and healthy cognitive aging.

Original languageEnglish (US)
Pages (from-to)273-279
Number of pages7
JournalJournal of Alzheimer's Disease
Volume34
Issue number1
DOIs
StatePublished - 2013

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LDL Cholesterol
HDL Cholesterol
Triglycerides
Dementia
Independent Living
Cognition
Japan
Cohort Studies
Prospective Studies
Lipids
Research
Cognitive Aging
oxidized low density lipoprotein

Keywords

  • Aged 80 and over
  • lipoprotein cholesterol
  • memory disorders

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Geriatrics and Gerontology
  • Clinical Psychology

Cite this

Very old adults with better memory function have higher low-density lipoprotein cholesterol levels and lower triglyceride to high-density lipoprotein cholesterol ratios : KOCOA project. / Katsumata, Yuriko; Todoriki, Hidemi; Higashiuesato, Yasushi; Yasura, Shotoku; Ohya, Yusuke; Willcox, D. Craig; Dodge, Hiroko.

In: Journal of Alzheimer's Disease, Vol. 34, No. 1, 2013, p. 273-279.

Research output: Contribution to journalArticle

Katsumata, Yuriko ; Todoriki, Hidemi ; Higashiuesato, Yasushi ; Yasura, Shotoku ; Ohya, Yusuke ; Willcox, D. Craig ; Dodge, Hiroko. / Very old adults with better memory function have higher low-density lipoprotein cholesterol levels and lower triglyceride to high-density lipoprotein cholesterol ratios : KOCOA project. In: Journal of Alzheimer's Disease. 2013 ; Vol. 34, No. 1. pp. 273-279.
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