Very old adults with better memory function have higher low-density lipoprotein cholesterol levels and lower triglyceride to high-density lipoprotein cholesterol ratios: KOCOA project

Yuriko Katsumata, Hidemi Todoriki, Yasushi Higashiuesato, Shotoku Yasura, Yusuke Ohya, D. Craig Willcox, Hiroko H. Dodge

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

We cross-sectionally examined which lipid profiles are associated with better cognitive function among those aged 80 and older, free of dementia (Clinical Dementia Rating ≤0.5), functionally independent, and community-dwelling. Our cohort consisted of 193 participants from the 'Keys to Optimal Cognitive Aging (KOCOA) Project', a prospective cohort study in Okinawa, Japan. Higher low-density lipoprotein cholesterol levels and lower triglyceride/high-density lipoprotein cholesterol (TG/HDL-C) ratios were associated with higher scores in memory performance after controlling for confounders. Further research is required to clarify the associations among LDL-C levels, TG/HDL-C ratios, and healthy cognitive aging.

Original languageEnglish (US)
Pages (from-to)273-279
Number of pages7
JournalJournal of Alzheimer's Disease
Volume34
Issue number1
DOIs
StatePublished - 2013

Keywords

  • Aged 80 and over
  • lipoprotein cholesterol
  • memory disorders

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Psychology
  • Geriatrics and Gerontology
  • Psychiatry and Mental health

Fingerprint Dive into the research topics of 'Very old adults with better memory function have higher low-density lipoprotein cholesterol levels and lower triglyceride to high-density lipoprotein cholesterol ratios: KOCOA project'. Together they form a unique fingerprint.

  • Cite this