Versatile reagents to introduce caged phosphates

Carlo Dinkel, Oliver Wichmann, Carsten Schultz

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Three novel reagents have been prepared to introduce photoactivatable o-nitrobenzyl phosphate esters. The use of fluorenylmethyl and t-butyl protecting groups allowed for a wide range of chemical transformations after phosphorylation. In addition, the use of S-acetylthioethyl and acyloxymethyl groups resulted in photo- and bioactivatable phosphate triesters of phosphatidic acid.

Original languageEnglish (US)
Pages (from-to)1153-1155
Number of pages3
JournalTetrahedron Letters
Volume44
Issue number6
DOIs
StatePublished - Feb 3 2003
Externally publishedYes

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Phosphates
Phosphatidic Acids
Phosphorylation
Esters

Keywords

  • AMP
  • Bioactivatable
  • Caged compounds
  • Mannose 1-phosphate
  • Membrane-permeant
  • Phosphatidic acid
  • Phosphorylation
  • Photoactivatable

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Versatile reagents to introduce caged phosphates. / Dinkel, Carlo; Wichmann, Oliver; Schultz, Carsten.

In: Tetrahedron Letters, Vol. 44, No. 6, 03.02.2003, p. 1153-1155.

Research output: Contribution to journalArticle

Dinkel, Carlo ; Wichmann, Oliver ; Schultz, Carsten. / Versatile reagents to introduce caged phosphates. In: Tetrahedron Letters. 2003 ; Vol. 44, No. 6. pp. 1153-1155.
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