Vasculitis in older patients: Presentations and significance

Vasculitis is commonly considered in the differential diagnosis of systemic disease in the elderly. Because the spectrum of vasculitis is so variable, it is useful to utilize a classification system that limits the diagnostic options. Classification systems based on potential pathologic mechanisms or specific histologic findings are of limited usefulness in the initial assessment of an elderly patient. A classification system based on the clinical features exhibited will be discussed in the context of vasculitic syndromes which may present in the elderly. While this approach is by no means comprehensive, it should allow the correct diagnosis of vasculitis in the majority of cases. Common and unique presentations of vasculitis in the elderly will also be discussed.