Variation in Antibiotic Susceptibility of Uropathogens by Age Among Ambulatory Pediatric Patients

Jessina C. McGregor, Yennie Quach, David T. Bearden, David H. Smith, Susan E. Sharp, Judith A. Guzman-Cottrill

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

We compared uropathogen antibiotic susceptibility across age groups of ambulatory pediatric patients. For Escherichia coli (n=5,099) and other Gram-negative rods (n=626), significant differences (p<0.05) existed across age groups for ampicillin, cefazolin, and trimethoprim/sulfamethoxazole susceptibility. In E. coli, differences in trimethoprim/sulfamethoxazole susceptibility varied from 79% in children under 2 to 88% in ages 16-18 (p<0.001), while ampicillin susceptibility varied from 30% in children under 2 to 53% in ages 2-5 (p=0.015). Uropathogen susceptibility to common urinary anti-infectives may be lower in the youngest children. Further investigation into these differences is needed to facilitate appropriate and prudent treatment of urinary tract infections.

Original languageEnglish (US)
Pages (from-to)152-157
Number of pages6
JournalJournal of pediatric nursing
Volume29
Issue number2
DOIs
StatePublished - Mar 1 2014

Keywords

  • Ambulatory care
  • Antibiotic resistance
  • Urinary tract infection

ASJC Scopus subject areas

  • Pediatrics

Fingerprint Dive into the research topics of 'Variation in Antibiotic Susceptibility of Uropathogens by Age Among Ambulatory Pediatric Patients'. Together they form a unique fingerprint.

  • Cite this