Variability of tissue optical properties in cancer patients receiving photodynamic therapy

S. L. Jacques, P. Bargo, T. Goodell, R. Sleven, G. Kovall, G. Blair

Research output: Contribution to journalConference articlepeer-review

1 Scopus citations

Abstract

Photodynamic Therapy (PDT) uses light to activate photosensitizive drug to yield oxidative injury to targeted tissues such as cancer. The ability of treatment light to penetrate a tissue and activate the drug that has accumulated in a target tissue depends on the tissue optical properties, especially the blood perfusion. An endoscopic spectroscopic probe was developed for monitoring esophageal and lung tissues and tested in patients in a pilot clinical study.

Original languageEnglish (US)
Pages (from-to)2283-2284
Number of pages2
JournalAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Volume3
StatePublished - Dec 1 2002
EventProceedings of the 2002 IEEE Engineering in Medicine and Biology 24th Annual Conference and the 2002 Fall Meeting of the Biomedical Engineering Society (BMES / EMBS) - Houston, TX, United States
Duration: Oct 23 2002Oct 26 2002

Keywords

  • Photodynamic therapy
  • Spectroscopy
  • Tissue optics

ASJC Scopus subject areas

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

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