@article{18f7262324344d13a0b8f74ab15062e3,
title = "Vaccine-induced linear epitope-specific antibodies to simian immunodeficiency virus SIVmac239 envelope are distinct from those induced to the human immunodeficiency virus type 1 envelope in nonhuman primates",
abstract = "To evaluate antibody specificities induced by simian immunodeficiency virus (SIV) versus human immunodeficiency virus type 1 (HIV-1) envelope antigens in nonhuman primate (NHP), we profiled binding antibody responses to linear epitopes in NHP studies with HIV-1 or SIV immunogens. We found that, overall, HIV-1 Env IgG responses were dominated by V3, with the notable exception of the responses to the vaccine strain A244 Env that were dominated by V2, whereas the anti-SIVmac239 Env responses were dominated by V2 regardless of the vaccine regimen.",
author = "Xiaoying Shen and Ryan Duffy and Robert Howington and Alethea Cope and Shanmugalakshmi Sadagopal and Haesun Park and Ranajit Pal and Suefen Kwa and Song Ding and Yang, {Otto O.} and Fouda, {Genevieve G.} and Grand, {Roger Le} and Diane Bolton and Mariano Esteban and Sanjay Phogat and Mario Roederer and Amara, {Rama R.} and Picker, {Louis J.} and Seder, {Robert A.} and {Juliana McElrath}, M. and Susan Barnett and Permar, {Sallie R.} and Robin Shattock and DeVico, {Anthony L.} and Felber, {Barbara K.} and Pavlakis, {George N.} and Giuseppe Pantaleo and Korber, {Bette T.} and Montefiori, {David C.} and Tomaras, {Georgia D.}",
note = "Publisher Copyright: {\textcopyright} 2015, American Society for Microbiology.",
year = "2015",
doi = "10.1128/JVI.03635-14",
language = "English (US)",
volume = "89",
pages = "8643--8650",
journal = "Journal of virology",
issn = "0022-538X",
publisher = "American Society for Microbiology",
number = "16",
}