@article{25cb43ec71ec45e7be9b74ac8de793d9,
title = "Uveal malignant melanoma in three generations of the same family",
abstract = "Three patients in three successive generations from the same family had choroidal malignant melanoma. The third generation patient had multiple primary malignancies; his siblings also had multiple malignancies. Chromosome studies of the third generation patient revealed no abnormality. To the best of our knowledge, this is the second such pedigree reported.",
author = "Walker, {Joseph P.} and Weiter, {John J.} and Albert, {Daniel M.} and Osborn, {Edward L.} and Weichselbaum, {Ralph R.}",
note = "Funding Information: Case 1—A 67-year-old man (third generation) who had had excision of facial basal and squamous cell carcinomas, complained of photophobia and decreased visual acuity in the left eye for several months. Examination revealed a best corrected visual acuity of R.E.: 6/9+ (20/30+) and L.E.: 6/15 (20/50). Examination of the anterior segment of the right eye disclosed early nuclear sclerosis of the lens. Examination of the anterior segment of the left eye revealed 1+ conjunctiva! injection, with 1 + From the Department of Ophthalmology, Tufts University School of Medicine, New England Medical Center Hospital and the Boston Veterans Administration Medical Center (Drs. Walker, Weiter, and Osborn), Boston, Massachusetts; the Howe Laboratory of Ophthalmology of Harvard Medical School at the Massachusetts Eye and Ear Infirmary (Dr. Albert), Boston, Massachusetts; and the Department of Radiation Therapy, Harvard Medical School, and the Laboratory of Radio-Biology, Harvard School of Public Health, (Dr. Weichselbaum), Boston, Massachusetts. This study was supported in part by a National Eye Institute Grant R01 EY 02246-01 and a Veterans Administration Merit Review Grant.",
year = "1979",
month = oct,
doi = "10.1016/0002-9394(79)90672-X",
language = "English (US)",
volume = "88",
pages = "723--726",
journal = "American Journal of Ophthalmology",
issn = "0002-9394",
publisher = "Elsevier USA",
number = "4",
}